Lecturer (~assistant professor) in Mathematical Biology @MathsLeedsUni. @TeamCanada team player, runner, kitchen disaster
Joined May 2009
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As a postdoc @LosAlamosNatLab, I had this fuzzy hope to use mathematical modelling in support of a clinical trial of HIV-1 treatments. I was very lucky to see that happen a few years ago; the mathematical details of that work are now out @PLOSCompBiol journals.plos.org/ploscompbi…
The details and results of the clinical trial are here
nature.com/articles/s41591-0… --It has been an absolute treat using mathematics to (hopefully) increase our understanding of HIV-1 broadly neutralizing antibodies
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We were lucky to have an exceptional few days of mathematical biology last week @UniversityLeeds; two fantastic seminars from @hamiscalculated and @adrianne_jenner on computational approaches to understand spatial and intra-patient heterogeneity in cancer #MathOnco
Even better, together with @a13xbrowning, @ChiaraVilla12, and @PhilipMaini, we spent the week thinking about the dynamics of phenotypic resistance to targeted anti-cancer therapies.
It was an incredibly fun week thinking about hard problems with with great collaborators.
In my everyday life, I'm often confused about the link between fit model parameters and experimental data. This recent paper in @SMB_MathBiology is my first step towards trying to puzzle my way through this relationship link.springer.com/article/10…
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Wonderful week surrounded by incredible people and so-so views. Grateful to @adrianne_jenner & @lab_craig for organizing and all the participants/new friends for the conversations, laughs, and new ideas
This week at BIRS: Computational Modelling of Cancer Biology and Treatments birs.ca/events/2023/5-day-wo…
The past 5 days have been a whirlwind, but I'm very excited start a lecturer (~assistant prof) position @mathsleedsuni. I wouldn't be here without all the wonderful mentorship and collaboration @beeshtylla @lab_craig (and many, many others) #AcademicTwitter #MathOnco
Saturday morning made infinitely better by the first letter from my @LettersPreSci pen-pal! She loves Nirvana, books, math, and the LA dodgers. I can’t wait to talk music, science careers, and if “science is ever boring” with her!
The absolute limit of my design abilities propped up by lots of help from @StroblMAR
"The Galton board of phenotypic plasticity and resistance to therapy," designed by @TCass20
Click here to read #MathOnco issue 184:
thisweekmathonco.substack.co…
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Using compartments to approximate delays in ODE models-especially if rates between compartments are constant-is standard in math bio. For nonlinear transitions with explicit delays, we show these models still hide delays epubs.siam.org/doi/10.1137/2…
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One of my favourite things about the vaccine is that at least one person will text me every day for the next 2 weeks #VSafe #VaccineForLoneliness
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There might be some neat things in this preprint, but the neatest is (by far) where @D4N__ @ara_anderson and I started piecing together the ideas
biorxiv.org/content/10.1101/…
I learned a ton during #IMLMathBio18 at the Institut Mittag-Leffler, but the biggest take aways were the conversations over dinner/exploring Stockholm/playing board games/singing in choirs with a pretty phenomenal group of scientists
A fun little (big) project on using computational perspectives to explore treatment space, test combination therapies, determine biological predictors of treatment response, and use structured models and in silico cohorts to explore intra- and inter- patient variability #MathOnco
Our paper on dual oncolytic viruses focused on optimizing schedules to enhance VSV OV jitc.bmj.com/content/9/2/e00… with @MarieClaudeBoDa is now out. Congrats to @adrianne_jenner @TCass20 and Katia for their hard work!
Exercise for readers: Try to find all the places @adrianne_jenner and I argued about verb use #AussieEnglish #Frenglish
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It's been a strange year. #BellLetsTalk ( a thread of experiences, strategies and musings) 1/n
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Collectively, we've made huge sacrifices to protect our communities #BellLetsTalk 2/n
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I spent 25 minutes on Powerpoint making this dream a reality and not nearly enough people have seen it. Happy 2021 everyone #WashHandsWearMasksBeKind
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@NMDEMS
I know I'm late to the party, but how can non-American citizens volunteer/help out in the next week? Asking for a Canadian in Santa Fe (me)
Beautiful Friday for letter writing in Santa Fe. Excited to connect with my new @LettersPreSci pen pal over about their dog, cooking and science. Even better, they don’t have to try to read my handwriting.
I know there is some serious #DeskClutter going on, but let’s just appreciate that my aloe has been alive for 4 months already #DontJinxIt #PlantPapa
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It'll never not be wild that my career is to use math to understand disease. I can't wait to share my everyday excitement with a 5th grade scientist! Stoked to meet my new #STEMPenPals! @LettersPreSci
Mathematician wasn't a career path when I was 12 and science was (and is) intimidating... so every year, @LettersPreSci pairs 5-10th grade student “pre-scientists” in US low-income communities with STEM professionals to humanize and demystify STEM careers.
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Watch me verbalize my jumbled/chaotic thought processes about math-online! With @CRM_Montreal, we've organized a "users guide" workshop to structured equations & delay equations in Math Biology. Registration: forms.gle/kSChoCuXLxx3xKxp8 #DontMissIt
Wonderful Thursday morning listening to an interesting and new (to me) perspective on tumour evolution
Today’s @mathonco seminar is from @robjohnnoble discussing: Characterizing and forecasting tumour evolution.
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