Joined October 2021
- Tweets202
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- Followers81
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Tooth Morphogenesis and Differentiation retweeted
This paper took us 13 years and is one of the longest papers ever in Cell. Check it out & judge for yourself
cell.com/cell/fulltext/S0092…
Just because epigenetic drift follows a predictable pattern doesn't necessarily mean it's causal in aging. Predictable patterns can form from stochastic reactions. Also you cannot fix all extracellular damages with cellular rejuvenation. More here: olafurpall.substack.com/p/wh…
Tooth Morphogenesis and Differentiation retweeted
scMultiSim is a comprehensive single-cell and spatial data simulator generating realistic multi-omics data based on modeling gene regulatory networks, cell-cell interactions, and other biological and technical factors nature.com/articles/s41592-0…
Tooth Morphogenesis and Differentiation retweeted
New article from our lab on the importance of squamate models for understanding key dental features of vertebrates is already online in @Dev_Bio_Journal as a pre-proof @BIOTECH_UH @HiLIFE_helsinki @helsinkiuni doi.org/10.1016/j.ydbio.2024…
Tooth Morphogenesis and Differentiation retweeted
It turns out...Komodo dragons have iron-coated teeth!
nature.com/articles/s41559-0…
Their serrations and tips pop into the mouth with an orange hue. Using different techniques, we show that these iconic lizards have special iron-rich coatings on each tooth, keeping them razor sharp!
Tooth Morphogenesis and Differentiation retweeted
Snakes have unique body plans, esp. in the skull. Embryonic description of Japanese rat snake reveals early ossification of palatine & pterygoid for swallowing large prey. Rapid prootic bone ossification aids in ground-borne sound detection
Nojiri et al.: doi.org/10.1002/ar.25539
Tooth Morphogenesis and Differentiation retweeted
Despite extensive study on Smilodon fatalis, their masticatory behaviors remain debated. Using osteological proxies from extant felids, researchers estimate gape & bite force, suggesting S. fatalis killed large prey with shearing bites.
Deutsch et al.: doi.org/10.1002/ar.25529
Tooth Morphogenesis and Differentiation retweeted
As part of the upcoming @LeverhulmeTrust research project on lizard enamel evolution, I will be recruiting a new (UK) PhD student for a 1st October start! If you or someone you know is interested, here is the advert link: findaphd.com/phds/project/en…
Tooth Morphogenesis and Differentiation retweeted
Proud to announce one of my PhD chapter is out in #OpenAccess in @CurrentBiology with @Val_Fisch @DavideTamagnin4 & @MargotMichaud00 🥳 Interested in evolutionary patterns of cat-like carnivorans? 🦁🔪 Here is a thread 🧵1/X doi.org/10.1016/j.cub.2024.0…
Tooth Morphogenesis and Differentiation retweeted
Really interesting new study by @Tseng_ZJ on prolonged canine eruption in saber-toothed carnivores!
"...the timing of the eruption of the sabers has been tweaked to allow a double-fang stage"
Media article: phys.org/news/2024-04-eviden…
@AnatRecord article: anatomypubs.onlinelibrary.wi…
Tooth Morphogenesis and Differentiation retweeted
Really excited to present the results of a great collaboration with the lab of @OphirKlein! 😃 A truly interdisciplinary effort, led by Neha and Pengfei, that reveals how tissue pressure sets the main tooth signaling center. Out today in @NatureCellBio
➡️ nature.com/articles/s41556-0…
Tooth Morphogenesis and Differentiation retweeted
Really cool paper about a tooth loss reversion phenotype in zebrafish by blocking RA degradation during tooth development!
pnas.org/doi/10.1073/pnas.23…
Tooth Morphogenesis and Differentiation retweeted
Gain-of-function mutations in Fibroblast growth factor receptor-3 (#FGFR3) cause #achondroplasia. #Infigratinib, a FGFR1-3 inhibitor, improves #skeletal growth in achondroplasia models, but detrimentally affects #craniofacial and #dentoalveolar tissues doi.org/10.1002/dvdy.642
Tooth Morphogenesis and Differentiation retweeted
MicroCT scans reveal insights into the tooth replacement pattern of the enigmatic Charruodon tetracuspidatus, a #Triassic #cynodont. Early ontogenetic stage hints at potential taxonomic mysteries! New research by Carolina Hoffmann et al.:
doi.org/10.1002/ar.25349
Tooth Morphogenesis and Differentiation retweeted
Excited to share our latest @Nature paper spearheaded by @YaelGruper identifying a new autoimmune disorder, characterized by impaired tooth development & generation of autoAbs against enamel matrix. It occurs in most AIRE def patients & ~1/3 of celiac kids nature.com/articles/s41586-0…
Tooth Morphogenesis and Differentiation retweeted
Mineralized #dental tissues such as #enamel and #dentin require tight transcriptional control of #matrix #protein secretion. Learn how the #odontogenic transcription factor #Msx2 regulates #enamalin during #amelogenesis and enamel biomineralization. doi.org/10.1002/dvdy.598 #Mouse
Tooth Morphogenesis and Differentiation retweeted
New genus and species characterized by distinctive molar morphology. #teeth #metatheria
Crichton et al 2023 et al 2023 Scientific Reports: A probable #koala from the Oligocene of central #Australia provides insights into early diprotodontian #evolution
doi.org/10.1038/s41598-023-4…
Tooth Morphogenesis and Differentiation retweeted
Insights gained from observing live and museum specimens help understand the chewing biology of hippos and yield instructions for reconstructing tooth positions in museum specimens. doi.org/10.1371/journal.pone…
Tooth Morphogenesis and Differentiation retweeted
600 baboons now scanned! 🎉🎉🎉 Thanks to the amazing collaboration with @AnthroLUC Only 400 left to go! @LoyolaChicago
@CENIEH @ERC_Research @FECYT_Ciencia #1000baboons
ALT 600 baboons now scanned! 🎉🎉🎉
Tooth Morphogenesis and Differentiation retweeted
FINALLY OUT! Using our beloved bats, we provide new insights regarding the origin of mammalian tooth classes and show how the interplay between multiple developmental mechanisms facilitates tooth diversification during evolution 🦇🦷#evodevo #tooth #bats nature.com/articles/s41467-0…
