Our new study in @GeroScienceAGE showed that each 1 µmol/L higher whole-blood NAD⁺ concentration, a coenzyme involved in energy metabolism, was associated with ~13% lower odds of frailty (OR 0.87) in 529 community-dwelling older adults. NAD⁺ may complement frailty assessment.

Our new study in Sleep Breath compared ActiGraph wGT3X+ with in-home portable EEG in 49 older adults across 217 nights. Total sleep time showed good agreement (ICC 0.73; 0.84 for multi-night averages; MAPE 11%), while accuracy was limited for sleep onset latency and WASO.

Our new study in Clin Nutr ESPEN established sex- and age-specific reference intervals for bioelectrical impedance analysis-derived phase angle in 4,484 older adults in Japan. Phase angle declined with age in both sexes, providing reference values for its interpretation.

We published a protocol in @BMJ_Open for a systematic review and meta-analysis examining adverse events associated with exercise interventions in older adults with frailty. The study will focus on safety by comparing the risk of adverse events between exercise and control groups.

We examined the association between oral frailty (OF) and well-being in older adults. OF was associated with lower well-being through undernutrition, depressive symptoms, and social isolation, suggesting that maintaining oral function may promote well-being in later life.

Our new study found that higher plasma pentosidine, an advanced glycation end-product marker, was associated with lower muscle mass, SPPB scores, and phase angles in community-dwelling older adults, suggesting a link between glycation stress and muscle health in later life.