The official Twitter account of the Genetic, Environmental, Microbial (GEM) Project. @sinaihealth supported by @getgutsycanada & @HelmsleyTrust

Toronto, Ontario
Joined March 2017
Childhood exposure + FCP >100 µg/g + a Blautia or Prevotella enriched enterotype defined a stratum with 22.5% 10-year cumulative CD incidence.
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In summary, childhood exposure to siblings with CD is an independent risk factor of CD onset, potentially mediated by early-life microbial perturbation.
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🌟 Honored to have my poster selected as a Poster of Distinction at #CDDW2026 on #DietaryFat, #AntiGMCSF autoantibodies, and #CrohnsDisease Grateful to contribute with the amazing @The_GEMProject team and mentors: Drs @TurpinWilliams, @KenCroitoru, @SunHoLee15, at @SinaiHealth
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The GEM Project team would like to congratulate @Jeongseok_Kim_ for his award for best abstract at #CDDWCLM2026! Check out his abstract here academic.oup.com/jcag/articl…
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The Gem Project Team was pleased to host @ProfWhelan for an insightful discussion into the current state of nutrition and its applications for IBD treatment and prevention. Thank you from all of us! @SinaiHealth @nutrisci_uoft @TurpinWilliams @KenCroitoru @SunHoLee15 @guthealthmd
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📢 New in Gastroenterology from PROMISE group: Prediction and Prevention of Inflammatory Bowel Disease: A Call to Action Summarizing the key points from the May 2025 PROMISE Workshop @LopesScopes @khalili_MD @JeanFredericCo1 @KenCroitoru #IngaPeter pubmed.ncbi.nlm.nih.gov/4141…
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As the global incidence of inflammatory bowel disease (IBD) continues to rise, innovative strategies for early identification, prevention, and treatment are urgently needed. The PROMISE (PRediction and PRevention through Omics, Microbiome, Immune System, and Environment) Consortium, is a collaborative initiative led by @IcahnMountSinai, @SinaiHealth, and @MassGeneralNews. Supported by Helmsley, PROMISE aims to advance prediction, prevention, and improved outcomes for individuals at risk of developing IBD. Recently, PROMISE convened an international group of multidisciplinary experts, patient advocates, and individuals with IBD to create a roadmap toward prevention–focused strategies and interventions. The group also engaged with Dr. Carla Greenbaum, a leading expert in type 1 diabetes prevention, to explore cross-disease learnings. Their roadmap has now been published in Gastroenterology—marking an important step toward a future where IBD can be predicted and prevented. Read the full white paper: bit.ly/4j6GUoZ #CrohnsDisease #IBDResearch #Prevention
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🚨 Don't miss the latest article from @IMSMagazine covering @SunHoLee15 work with the GEM Project! With GEM’s unique dataset, Dr. Lee is helping to pave the way for precision medicine in IBD care and prevention. #PrecisionMedicine #IBDResearch imsmagazine.com/2025/01/27/g…
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Innovative research is essential for enhancing our understanding of Crohn’s disease and advancing the development of future preventative therapies. Helmsley supported the Genetic, Environmental, Microbial (GEM) Project , which aimed to predict an individual’s risk of developing Crohn’s disease, identify methods to prevent the disease before symptoms arise, and develop new treatments for those already affected. Recent studies from the GEM Project highlight the connection between environmental factors and healthy individuals with a family history of the condition. Read more about this work: bit.ly/3CK5NWp #CrohnsDisease #CrohnsAwareness
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Congratulations to @AlexanderLuchak for successfully defending his PhD at the Department of Immunology @UofT! Alec's work in murine models of IBD has helped uncover potential mechanisms of IBD @KenCroitoru #DanaPhilpot @TheGEMProject @TurpinWilliams @Sunholee15 @BHUPESHTHAKUR30
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Excellent talk about Role of anti-microbial immunity in IBD @ivanvujk at the Biology of IBD Rounds @SinaiHealth @UofTGastroHep @KenCroitoru @TurpinWilliams @The_GEMProject @guthealthmd @laura_tee_mdgi @hsteinhart @vwaimeih @RichardYouWu @zanegallinger
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