Área de conocimiento Tiroides de la Sociedad Española de Endocrinología y Nutrición #EmbajadorSEEN
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ALT European Thyroid Journal logo - TERT promoter mutations in papillary thyroid carcinoma: association with gross extrathyroidal invasion and outcomes By Debora L S Danilovic et al. - Figure 2. (A) DFS of papillary thyroid carcinoma with mETE, gETE-T3 and gETE-T4. (B) Cox proportional hazards regression analysis. DFS, disease-free survival; LNM, lymph node metastases; DM, distant metastases; RAI, radioiodine; HR, hazard ratio (95% confidence interval); a, hazard ratio adjusted for male sex, age, tumor size >4 cm, unfavorable histology, multifocality, lymphovascular invasion, LNM or DM at initial therapy, and initial RAI therapy. Eur Thyroid J (2026) 15 (5): ETJ260128. doi.org/10.1530/ETJ-26-0128
ALT European Thyroid Journal logo. European Thyroid Association logo. - Intranodular lactate for thyroid nodule assessment: universal performance and maximum impact in indeterminate cytology By Luis-Mauricio Hurtado-Lopez et al. - Figure 1. Intranodular lactate concentration (mmol/L) across extranodular thyroid parenchyma, benign nodules, and malignant nodules. Boxes denote the interquartile range (IQR), the central line the median, and whiskers the 1.5×IQR range; individual measurements are overlaid. Lactate increased progressively from healthy tissue too benign and too malignant nodules, consistent with enhanced aerobic glycolysis (Warburg effect). Eur Thyroid J (2026) 15 (5): ETJ260216. doi.org/10.1530/ETJ-26-0216
![[European Thyroid Journal logo] Association of TP53 mutational status and survival in anaplastic thyroid cancer treated with dabrafenib plus trametinib Ricardo Rodrigues et al. - Figure 1. TP53 mutations and association with clinical variables and treatment outcomes. (A) Association between TP53 mutations and overall survival. (B) Association between TP53 mutations and progression-free survival. (C) Association between TP53 mutations and duration of response. Waterfall plots of the association between TP53 mutations and the magnitude of response at the best response timepoint, in the full cohort (D) and in the subgroup with partial responses. (E) Waterfall plots of the association between TP53 mutations and the magnitude of response at the end of the follow-up in the full cohort (F) and in the subgroup with partial responses (G). - Eur Thyroid J (2026) 15 (5): ETJ260135. doi.org/10.1530/ETJ-26-0135](https://pbs.twimg.com/media/HVPsiv5XUAAAEZq.jpg?name=orig)
ALT [European Thyroid Journal logo] Association of TP53 mutational status and survival in anaplastic thyroid cancer treated with dabrafenib plus trametinib Ricardo Rodrigues et al. - Figure 1. TP53 mutations and association with clinical variables and treatment outcomes. (A) Association between TP53 mutations and overall survival. (B) Association between TP53 mutations and progression-free survival. (C) Association between TP53 mutations and duration of response. Waterfall plots of the association between TP53 mutations and the magnitude of response at the best response timepoint, in the full cohort (D) and in the subgroup with partial responses. (E) Waterfall plots of the association between TP53 mutations and the magnitude of response at the end of the follow-up in the full cohort (F) and in the subgroup with partial responses (G). - Eur Thyroid J (2026) 15 (5): ETJ260135. doi.org/10.1530/ETJ-26-0135
