October issue @TransplantJrnl ◼ From Gene-Editing to Exogenesis: Pigs as a Source of Immune-Compatible Organs for Transplantation ◼ Organ Assessment and Repair Centers: Navigating Practical Hurdles in a New Era of Transplantation And More bit.ly/TPAissue

Moving normothermic liver perfusion into the OPO: fewer turndowns, more DCD livers used, and 94.6% 1-year survival at a partner center. A scalable, sustainable, equitable model for expanding access to liver transplantation. #TXPforAll #Transplantation tinyurl.com/4ywsucv8

#TBT to this week's featured top downloaded paper from 2024: Supporting Financial Neutrality in Donation of Organs, Cells, and Tissues #Transplantation #Med tinyurl.com/mpnh6dk2

This study puts long-term ex situ preservation to the test using normothermic machine perfusion (NMP) on a standard, commercially available OrganOx Metra—no hardware modifications needed. #TXPforAll #Transplantation #OpenAccess tinyurl.com/24es7hmt

This paper summarises the highlights of the 5th Summit on Stem Cell-Derived Islets, which showcased significant progress in islet biology, immunoprotection, scalable manufacturing and clinical transplantation. #TXPforAll #Transplantation #OpenAccess tinyurl.com/yx2bazz3

#TBT to this week's featured top downloaded paper from 2024:Disparities Affecting Organ Donation Rates in Chile #Transplantation #Med tinyurl.com/3zarvbnj

This review addresses the question of whether Regional Organ Assessment and Repair Centres could help to unlock more and better donor organs. #TXPforAll #Transplantation tinyurl.com/mrnzkmwf

🌍 A global analysis of LT activity vs. cirrhosis burden (2000–2023) reveals a striking mismatch: LT is concentrated in high- sociodemographic Index (SDI) countries, while low-SDI countries have very limited access and rely heavily on living donors. tinyurl.com/4y4p8bka

#TBT to this week's featured top downloaded paper from 2024:Anti-CD38 Monoclonals for Treatment of Antibody-mediated Rejection in Renal Allografts #Transplantation #Med tinyurl.com/4uc54d4b

This review reports on the use of functional and molecular biomarkers during machine perfusion to assess graft quality in real time, and emphasises the need for validated, standardised tools to improve outcome prediction. #TXPforAll #Transplantation tinyurl.com/4sew3sz5

This review explores the potential of combining donor and recipient genetics to advance precision transplantation using polygenic risk scores, while highlighting the key challenges to clinical implementation. #TXPforAll #Transplantation tinyurl.com/2tm4c7ca

#TBT to this week's featured top downloaded paper from 2024: Functional Natural Killer-cell Genetics and Microvascular Inflammation After Kidney Transplantation: An Observational Cohort Study #Transplantation #Med tinyurl.com/4bab76n5

🌍 A global survey across 64 countries highlights the scale and complexity of international travel for organ transplantation (ITOT) and the need for stronger data, governance and equitable access. #TXPforAll #Transplantation #Organdonatio tinyurl.com/2z379usk

This review by Diebold et al. explains how natural killer (NK) cells contribute to kidney allograft injury beyond their classic role in innate immunity. #TXPforAll #Transplantation #Immunology tinyurl.com/yccxurnk

#TBT to this week's featured top downloaded paper from 2024:Insights From Refusal Patterns for Deceased Donor Kidney Offers #Transplantation #Med tinyurl.com/3b5mxzud

This review paper explains why solid organ transplant recipients are at increased risk of HPV-associated anal cancer. #TXPforAll #Transplantation #Infection tinyurl.com/yeu3b3vv

#TBT to this week's featured top downloaded paper from 2024:Promoting Equitable and Affordable Patient Access to Safe and Effective Innovations in Donation and Transplantation of Substances of Human Origin and Derived Therapies #Transplantation #Med tinyurl.com/yu6dsep3

🫁 Promising findings in lung transplantation: S1PR1 activation with CYM5442 during EVLP reduced pulmonary edema, lung weight gain, pressures, and inflammatory mediator release while preserving endothelial integrity. #TXPforAll #Immunology #Transplantation tinyurl.com/36jts4m3

Exciting Results: In 204 HCV-negative recipients of kidneys from HCV-viremic donors, 7-day sofosbuvir/velpatasvir prophylaxis resulted in 100% overall SVR12 after retreatment, with excellent 1-year patient and graft survival. #TXPforAll #Transplantation tinyurl.com/3m32prtb

#TBT to this week's featured top downloaded paper from 2024:Use of Ex Situ Machine Perfusion for Liver Transplantation: The National Experience #Transplantation #Med tinyurl.com/4ytjy9u7