ChenLabToledo retweeted
Join the Membrane Structure & Function Subgroup on Tuesday, September 15 from 11:00 am- 12:00 pm EST for their virtual program, "Lipids Feeling the World" where we will explore cutting edge work on lipid-biomembrane interations.
Register Now!
buff.ly/pBxlZTE
ChenLabToledo retweeted
Actin ♥️
Intact Actin: Tag called IntAct-U-ExM enables super-resolution of actin networks by expansion microscopy
📸 @anubhav_dhar et al @syncellbiolab @iiscbangalore in @PLOSBiology
➡️ bpod.org.uk/archive/2026/8/2… with @AntDLewis
ChenLabToledo retweeted
Obituary: Susumu Tonegawa (1939-2026) Japan’s first Nobel prizewinner in physiology or medicine
go.nature.com/4pNgJXN
ChenLabToledo retweeted
From MBoC
Optogenetic activation of RhoA reveals a direct mechanism for local septin recruitment. The findings show that RhoA signaling—not myosin contractility—drives septin remodeling in interphase cells.
molbiolcell.org/doi/10.1091/…
ChenLabToledo retweeted
Ani Michaud, @GoryachevAndrew, von Dassow, @BementLab et al. identify a versatile cortical pattern-forming circuit based on #Rho, F-#actin, Ect2, and RGA-3/4: hubs.la/Q04p9X4Y0
📕 Part of “Collective Behaviors and Self-Organization in Cells”: hubs.la/Q04p9ZLw0
ChenLabToledo retweeted
Spotlight: Williams et al. (hubs.la/Q04mkH960) show that chromosome segregation is independent of separase-mediated feedback and that synchrony is affected by a small number of stochastic effects. Boland @Biologie_UNIGE discusses the findings: hubs.la/Q04mkw6g0
ChenLabToledo retweeted
🔬 Cell-type-specific GCaMP6 miniscope imaging of a freely-behaving mouse brain. ~1,200 excitatory CA1 hippocampal neurons were imaged during active behavior over months.
Courtesy of the Schnitzer Lab, Stanford.
#MicroscopyMonday #Neuroscience #Lifescience
ChenLabToledo retweeted
In the latest issue! Calcium signaling in plants: Universal and unique paradigms dlvr.it/TR7bm8
ChenLabToledo retweeted
Protocol to identify mechanosensitive nuclear proteins using tunable actomyosin contractility and proximity biotinylation in mammalian cells @StarProtocols #bps2026 hubs.ly/Q04482qB0
ChenLabToledo retweeted
Step-by-step protocol and reproducibility
Generate iPSC-derived 3D neurospheres for neuron–glia studies.
Date: March 25 | Time: 12:00 pm ET
Free
Register: ascb.org/ascb-meetings/3d-hu…
ChenLabToledo retweeted
Cell Bio 2026 is built by scientists, for scientists—and it starts with your ideas.
Submit a scientific session proposal and help shape the program.
🗓 Deadline: February 22, 2026
Submit Now: ascb.org/cellbio2026/
ChenLabToledo retweeted
.@richa_rikhy lab @IISERPune show Drosophila Missing-in-Metastasis (DMIM) (also called MTSS1) promotes Rac1 mediated branched actin network formation & endocytosis to drive rapid, cyclical plasma membrane remodeling during embryonic syncytial divisions hubs.la/Q040wrqn0
ChenLabToledo retweeted
AlphaGenome is out in @nature today along with model weights! 🧬
📄 Paper: nature.com/articles/s41586-0…
💻 Weights: github.com/google-deepmind/a…
Getting here wasn’t a straight path. We sat down @googledeepmind to discuss the story behind the model, paper & API: youtu.be/V8lhUqKqzUc
ChenLabToledo retweeted
Cell biology for a sustainable future – a call to action from Camila Costa, Eliott Flaum, Delfina Hlashwayo @DHlashwayo, Marie Jacobovitz, Guillermina Kubaczka, Samuel Lovat, Eliya Milshtein, Hanna Szafranska @HannaSzafransk1 and Soraya Zwahlen.
journals.biologists.com/jcs/…
ALT Drawing showing that planetary cell biology is a field that combines environmental sciences and cell biology. Understanding cellular function and its environmental context can be useful in explaining larger-scale systems operating at the multicellular and ecological levels. Furthermore, planetary cell biology provides key insights into how biological systems might adapt, be resilient to, and even mitigate, environmental perturbations associated with the climate crisis, such as changes in temperature, pH, pressure and other conditions.
ChenLabToledo retweeted
Review: Siqi Deng, Zhiqiang Yan et al. @hkust summarize the physiological functions and structural basis of OSCA/TMEM63 proteins, positioning them within a mechanosensitive ion channel superfamily. hubs.la/Q03ZL0yH0
#Physiology #Neuroscience #Mechanobiology #IonChannels
ChenLabToledo retweeted
New research from Lee, Higgs et al. @GeiselMed shows how #INF2, a key #actin regulator, is activated by calcium-calmodulin and free actin monomers. Actin-binding proteins like profilin and thymosin aren't just helpers - they directly tune INF2 activity. hubs.la/Q03ZT5_k0
ChenLabToledo retweeted
This study presents new tools for measuring the intracellular calcium concentration close to transmitter release sites, which may be relevant for synaptic vesicle fusion and replenishment.
elifesciences.org/reviewed-p…
ChenLabToledo retweeted
@NIH has launched the nation’s first dedicated Organoid Development Center to accelerate human-based research and to complement animal models. The center will support new 3D tissue models to study disease, drug response, and human biology.
bit.ly/4pBYT9T
ALT NIAID sourced image depicting Brain organoid depicting neural stem cells in green and neurons in magenta. Both cell types are abundant, showing normal development.
ChenLabToledo retweeted
Spotlight: Ivan Radin discusses new work from Ryken et al. (hubs.la/Q03YtQV90) which shows how localization and function of autoinhibitory calcium ATPases maintains the strength of the tip-focus Ca2²⁺ gradient during polarized plant growth. hubs.la/Q03YtTq30
ChenLabToledo retweeted
This study presents new tools for measuring the intracellular calcium concentration close to transmitter release sites, which may be relevant for synaptic vesicle fusion and replenishment.
elifesciences.org/reviewed-p…