Palo Alto, New York, Boston
Joined January 2009
🎙On the latest Running Through Walls episode, @Nimish1316 chats with @dianthustx CEO Marino Garcia about lessons from his 30+ years in biotech, his journey to CEO, advice for emerging leaders, and more. Listen here: bit.ly/4yWBlAE
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Join us in Shanghai for the 13th @BioCentury China Healthcare Summit, Nov 2-4. Venrock is proud to sponsor this year’s event, where Ken Song will join BioCentury's Simone Fishburn for a fireside chat exploring company building in the industry. Register: bit.ly/4iAULoY
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🎙On our latest episode of Running Through Walls, Andrew Gottesdiener and @Nimish1316 sat down with Michael Henderson, CEO of Apogee Therapeutics, to talk about selling Apogee to AbbVie for nearly $11 billion, the hardest part of being a CEO, and more. bit.ly/4hs6RA8
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We closed a $275 million financing co-led by GV and another healthcare fund, with support from new and existing investors. Funding will advance ETX101 for Dravet syndrome and support broader pipeline advancement. Learn more encoded.com/encoded-therapeu…
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Venrock retweeted
Huge news: @Vanguard is acquiring @Altruist 🚀🚀🚀. Congrats to @jasonwenk & the Altruist team!! It’s been awesome working together for the past 8 years as you’ve revolutionized wealth management 🙏🙏. May you have many more “Altruist moments”!! @Venrock wsj.com/business/deals/vangu…
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🎙What if primary care was easier to access, free for employees, and built to lower healthcare costs? Tune in to Running Through Walls to hear Siobhan Nolan Mangini and @bobkocher discuss this idea with @AlignedMP CEO Patrick Nelli: bit.ly/3SjMtrl
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Enterprise AI is in a wildly paradoxical state 🤔, and we’re reaching the inflection point that will resolve it. 💥 Enterprises want to differentiate with AI, yet rent the same intelligence as their competitors. Their workflows and expertise are highly specialized, yet they rely on generic models built to be good at everything. They worry about AI costs, yet pay premium prices for massive models where only a fraction (1%) of the intelligence is relevant to their task. 💸 And they demand control and sovereignty, yet rent the intelligence becoming core to their business. This is not a sustainable equilibrium. The next era of enterprise AI is specialized intelligence companies build, own, and compound. And we are at the inflection point of this transition. That’s the bet we made when we started @oumi_ai two years ago. Today we’re closing the loop: Oumi can now not only automatically build your specialized AI models, but also deploy them into production, learn from their production experience, and continuously improve them. The intelligence that your business runs on, becomes your differentiator. Your compounding advantage. The winners of the next AI era will turn their own data, expertise, and experience into specialized intelligence that nobody else can rent. Don’t rent your AI. Build it. Own it. Compound it.
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Our 10th annual #HealthcarePrognosis found a meaningful shift in sentiment: 73% of respondents say they have warmed up to AI-assisted care. Does this surprise you? hcprognosis2026.venrock.com/
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What’s next for healthcare? On the latest #RunningThroughWalls, Bryan, Bob and Siobhan unpack our 10th annual Healthcare Prognosis results. From AI trust to oral GLP-1 adoption to the state of exits, you won’t want to miss it. venrock.com/podcasts/healthc…
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📣Our 10th annual #HealthcarePrognosis is out! From AI-assisted care to consumer peptides to OpenEvidence and the health tech IPO window, over 200 #healthcare experts shared their views on the future state of our world. Check it out: hcprognosis2026.venrock.com/
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Venrock retweeted
This morning, I am thrilled to announce that Arca has officially emerged from stealth with $64 million in funding across our seed and Series A from @generalcatalyst , @IndexVentures , and @Venrock . I started Arca because of a simple contradiction: the best wealth management is deeply personal, yet the industry becomes less personal as it scales. We know great financial advisors don't just manage portfolios – they help clients navigate life's biggest, most emotional decisions. But most advisors are buried in administrative work, fragmented systems, and inefficient manual workflows, preventing them from doing their best work for their clients. We believe more people deserve personalized, proactive and efficient wealth management. And advisors deserve to focus on what they do best: delivering great financial advice to their clients. That's why Arca was born. Arca is an AI-native wealth management company that is redefining how financial advice is delivered by pairing great financial advisors with a fully integrated, agentic platform. We’re building agents from scratch across every part of the business, creating an evolving and compounding system that learns from and operates itself, and pushing the boundaries of what’s possible in one of the largest industries in the world. We're empowering advisors to do what only humans can do: cultivate trust and relationships, understand the full complexity of someone’s financial life, and make every client feel deeply seen and heard. Thank you to our fantastic team for joining this journey; we would not be here without your efforts. We're building one of the most talent dense teams in NYC, and we're hiring across the board. To our investors and board/advisors, I'm grateful for your belief and support in Arca and our vision of working tirelessly to enable better financial outcomes for people. Learn more about Arca’s story in our WSJ exclusive: wsj.com/pro/private-equity/s…
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🎙What makes a biotech strategically impossible to ignore? @MetseraInc CEO Whit Bernard joins @Nimish1316 on Running Through Walls to discuss obesity therapeutics, pharma bidding wars, and building with first-principles conviction. Listen here: bit.ly/4uWFrWG
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🎙In biotech, the biggest calls often come years before the data. On Running Through Walls, @Nimish1316 speaks with @CogentBio CEO Andy Robbins about targeted therapies, AI in drug development, and building with patients in mind: bit.ly/4a8LIqF
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🎙In our latest Running Through Walls episode, @SmithRx_PBM CEO Jake Frenz and Venrock’s Siobhan Nolan Mangini dig into what it takes to rebuild a drug ecosystem with patients at the center. Tune in to hear more: bit.ly/4dsDyeP
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.@BRobertsVC joined the @healthtechnerds podcast to discuss Venrock's thesis in seeding @KeloniaTx, which was recently acquired by Eli Lilly for up to $7B. Check out the episode here (Bryan joins at 36:08):  podcasts.apple.com/us/podcas…
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Great panel at @StartupGrind with @ethanjb from @venrock on being the first Physical AI company. Hard part: most people won't believe you or understand it. The best decision: getting the @PhysicalAI handle early. Documented proof matters when everyone jumps on the bandwagon.
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We're excited to announce that Mariana Mihalusova and Phil DiGiacomo have been promoted to partner. They’ve both made meaningful contributions across our biotech and life sciences portfolio, and we’re excited for their continued success at Venrock. venrock.com/insights/mariana…
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🎙On an episode of Running Through Walls, @bobkocher sits down with @BStulberg to talk about his new book, The Way of Excellence. If you’re on the precipice of chasing something big, tune in for invaluable tips for success while finding joy along the way: bit.ly/4dCzQjt
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🎙We’re back with a conversation between one of the greatest minds in AI research @MelMitchell1 of the @sfiscience and @ethanjb. Tune in for perspectives on AI capabilities, performance benchmarks, and the path forward that’s grounded in evidence: bit.ly/3PFyYAF
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