WEAVER Lab at UT Southwestern Gene-Environment Interactions in Signaling and Regenerative Biology #Proteostasis #Signaling #Aging #Metabolism #Stress #EvoDevo

UT Southwestern Dallas TX
Joined March 2023
Employing protein tagging, scientists identify interaction networks centered on the #p38 homolog PMK-1 in C. elegans that facilitate phenotypic plasticity during development, in several tissue types, and in response to stresses and aging. @UTSWMedCenter scim.ag/3QUnIAT
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Don’t miss the new issue of #ScienceSignaling! Scientists uncover the molecular wiring that supports phenotypic plasticity in C. elegans, a new Focus explores community resources that will propel the next era of lipidomics research, and more. scim.ag/4toWMXK
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Check out our highlight of the most recent example of subcellular mitochondrial specialization in @CurrentBiology. Be sure to also check out the beautiful work from David Sherwood's lab cell.com/current-biology/ful…
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These sea turtles dance for joy when they magnetically sense it’s snack time. Learn more on #WorldTurtleDay: scim.ag/4hZLGDf
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Principal Investigator Yuh Min Chook (@yuhminchook) and researchers at @UTSWMedCenter advance our understanding of the diversity of signals that drive nuclear export and how cargo phosphorylation is crucial in regulating nuclear transport and controlling cellular signaling pathways. nature.com/articles/s41467-0…
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I am beyond thrilled to become a Searle Scholar! Thank you @CRI_UTSW, @SJMorrison_ @RalphDeBerardinis (no longer on X), @RobertoZoncu for all your support and mentorship!
Congrats, @HijaiShin 👏👏 CRI's newest investigator has been named a 2025 Searle Scholar to support her #relentlessdiscovery & innovative research on lysosomes. From her discovery of LYCHOS to future plans, read more ➡️cri.utsw.edu/shin-named-2025…
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In this month's Editorial we discuss why basic research is the backbone of advances in medicine and improvements to the human condition - and that basic research needs essential support from government funding. nature.com/articles/s41592-0…
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G&D’s Editor-In-Chief, Professor Andy Dillin is attending the 2025 @ASBMB Annual Meeting in Chicago. #ASBMB25 #MakeItPossible If you’d like to share your work with us or learn about the journal, feel free to drop by or reach out at [email protected] @GenesDev @dillinlab
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With its UFO-like display, the cuttlefish may look like it’s trying to get attention—but its intent is anything but. The undulating black stripes confuse prey, making the creatures all but invisible to crabs and other victims: scim.ag/4c91RMB @NewsfromScience
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Ben Weaver retweeted
A species of comb jelly (Mnemiopsis leidyi) can age backward when stressed, reversing its development from a sexually mature life cycle stage to an earlier larval stage—a finding relevant to the study of aging and rejuvenation in animals. In PNAS: ow.ly/qRqQ50U1AtH
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MEF2 is upregulated during cardiac hypertrophy and is required for normal post-natal growth of the myocardium: Current Biology cell.com/current-biology/ful… 25 years ago this week, the Megeney lab published its very first paper and the story has stood the test of time!
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SMCHD1 activates the expression of genes required for the expansion of human myoblasts academic.oup.com/nar/article… Wonderful collaboration with Dr. Jeff Dilworth, paper just out in Nucleic Acids Research, SMCHD1 as a modifier of Facioscapulohumeral Muscular Dystrophy
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The count down is on! Will be a great gathering in Ottawa, looking forward to hearing some great science.
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Delighted to share new work led by Josh Meisel w/Gary Ruvkun using forward genetics to discover a new mode of post-transcriptional gene regulation. The mechanism involves mRNA methylation and P-bodies to allow neuron-specific mitochondrial gene expression. tinyurl.com/amnjyr5u
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Many thanks to @GeisbrechtE_Lab and @BiPengpeng for a nice Dispatch in @CurrentBiology featuring our recent paper on how steroid hormone signaling regulates myoblast fusion: cell.com/current-biology/ful…
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Deadline approaching‼️Submit your abstract by April 2 to apply for a talk at #Ubiquitin&Friends 2024. Great chance for students, #postdocs & #ECRs to present & discuss your work with peers&experts in a friendly atmosphere (& visit Vienna!) #ubfriends2024 ➡️protein-degradation.org/symp…
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Ben Weaver retweeted
Happy to have this invited Opinion article out in @Dev_Cell. I highlight the changing landscape of the lipid biology field as it embraces omics-oriented methods. I humbly try to discuss a challenge of our times: how to make big data useful & accessible? authors.elsevier.com/a/1iki4…
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So happy to see our review online in @NatureCellBio - “Lipid droplets and cellular lipid flux” - lead by super star grad student @alymathiowetz! Droplet biogenesis/ turnover, contacts and lipid transfer, roles in lipotoxicity / cell death, and more! 🎉 nature.com/articles/s41556-0… – at Orinda, CA
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