The Wermeling lab at the Karolinska Institutet – Research related to Autoimmunity, Cancer immunotherapy, hematopoiesis, and CRISPR/Cas9

Stockholm, Sweden
Joined August 2020
Friends! I'm delighted to share the heroic work by @longjiang1988 in collaboration with the Prof. David Lane lab, aiming to identify parameters of potential relevance for CRISPR-based precision medicine. 1/x Spotify: tinyurl.com/4587vta8 Paper: tinyurl.com/yzptcs35
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Thanks everyone involved for making our CRISPR symposium such a success! 151 participants and fantastic presentations. @tuuliel, @JohnDoench, @nevillesanjana, @Alifeinscience, @jcornlab, @randall_platt, @JennaPersson, Douglas Ross Thriepland, Erik Shifrut, Yumeng Mao.
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Thanks to co-organizer Bernhard Schmiere and Therese Huldtgren from Akademikonferens for all their efforts. We are grateful to @Cancerfonden, @karolinskainst, @scilifelab, Phenotarget, @idtdna, @Synthego, Countage, @ParseBio, BioNordika, and Singleron Biotech for their support!
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I´m super proud and impressed by Vaish Iyer who got her PhD title today after an epic discussion with opponent Anne Spurkland (@anspurk). The defense was completely conducted by the white board, and extra pens, and fans (!) were delivered halfway through the discussion...
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Vaish has nailed here thesis! A great achievement and milestone.
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Very excited to share our latest research on immunological features of #LongCovid. Our 2+ year collaboration with @PutrinoLab with many other fantastic colleagues and patients - Mount Sinai Yale Long COVID (MY-LC) study by @sneakyvirus1 et al. 🧵(1/) medrxiv.org/content/10.1101/…
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Fredrik Wermeling retweeted
Earlier this week, NYPD arrested Jazz Ajilo, a beloved subway musician. New Yorkers were outraged. In response, Mayor Adams said the subway is out of control and he was elected to fix it. It’s “not the place for disorder.” So…here’s a thread of that…“disorder”.🧵
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Super proud of the work by Vaishnavi Iyer developing antisense oligonucleotides to modulate T-cell activation. Great collaboration with labs at @Karolinskainst and @NTUsg. As always, the linked soundtrack: tinyurl.com/mr2avjs6 Paper: tinyurl.com/mwva7xm3
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Congratulations to @longjiang1988 (my first PhD student!) for successfully defending his thesis today in a great manner! Big thanks to opponent @rajchari2, as well as committee Galina Selivanova, Gisela Barbany, and @ERICPBENNETT. @karolinskainst #PhD #Zoom
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Fredrik Wermeling retweeted
CRISPR-mediated DNA damage enriches for cells with escape mutations in a broad CRISPR p53 interactome. Jiang et al identify parameters affecting the enrichment, and show that it can be suppressed by transient inhibition of p53. bit.ly/3GedfG9 @Wermeling_lab
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Generous funding was provided by @karolinskainst, @Vetenskapsradet, @Cancerfonden, Magnus Bergvalls stiftelse, as well as the KI - CSC and KI - @NTUsg PhD programs, and support from the National Genomics Infrastructure @scilifelab and #SNIC, Uppsala.
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Also thanks to @CR_AACR for their impressively fast review process!