yacine.maringer (@YMaringer) profile picture

yacine.maringer

@YMaringer

PostDoc @LabWalz

 Tübingen, Germany
Joined June 2020
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  • Following67
  • Followers47
Happy to announce that Jens Bauer from our lab together with Ashish Goyal and Joschka Hey were awarded the #WaltraudLewenzPreis 2023 @DKFZ for their work on "DNMT and HDAC inhibition induces immunogenic neoantigens from human endogenous retroviral element-derived transcripts".
Image from Peptide-based Immunotherapy (@LabWalz)
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yacine.maringer retweeted
DKFZ (@DKFZ) profile picture
DKFZ@DKFZ12 Apr 2024
Ashish Goyal, Jens Bauer und Joschka Hey erhalten den diesjährigen #WaltraudLewenzPreis für ihre Arbeit über die Identifizierung von Neoantigenen, die von neu aktivierten Transkripten bei epigenetischen Therapien kodiert werden. Herzlichen Glückwunsch! 👏 @DKTK_
Image from DKFZ (@DKFZ)
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Interesting paper by Wang et al. in @Nature analyzing the circadian rhythm of DCs in mice, and its potential impact on #Cancer #Immunotherapy. nature.com/articles/s41586-0…
Dendritic cells direct circadian anti-tumour immune responses

Dendritic cells direct circadian anti-tumour immune responses

Nature - Rhythmic trafficking of dendritic cells to the tumour draining lymph node governs a circadian response of tumour-antigen-specific CD8+ T cells that is dependent on the circadian expression...

nature.com
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Enjoying the #conference as a #team @CoE_iFIT #iFIT2023 #cancer #Immunotherapy
Image from Peptide-based Immunotherapy (@LabWalz)
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We are very excited to share our work published in @SciImmunology showing that different #vaccination regimens induce broad and long-lasting spike-specific CD4+ and CD8+ #Tcell immunity that is not further enhanced by booster vaccination: science.org/doi/10.1126/scii…

Durable spike-specific T cell responses after different COVID-19 vaccination regimens are not...

Durable T cell responses with Omicron cross-recognition are observed after complete and booster vaccination with different COVID-19 vaccines.

science.org
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In a new study, researchers evaluate immune responses of several #SARSCoV2 vaccines in people, showing that while boosters improve antibody responses, they do not do so as robustly for #Tcells. @YMaringer @LabWalz @uni_tue 📄: scim.ag/nD
Image from Science Immunology (@SciImmunology)
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An oncogenic fusion protein as target for novel #immunotherapies of cancer. We are so excited to share our study, which identified the oncogenic fusion protein DNAJB1-PRKACA as source of #neoantigens for peptide-based immunotherapy in #FLHCC! nature.com/articles/s41467-0…

The oncogenic fusion protein DNAJB1-PRKACA can be specifically targeted by peptide-based immunoth...

Nature Communications - The DNAJB1-PRKACA fusion transcript is the oncogenic driver in fibrolamellar hepatocellular carcinoma, a lethal disease with limited therapeutic options. Here, the authors...

nature.com
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We are looking for a new #research secretary. Join our great team and comfortable working environment, @Salihlab. For more details check out the following link medizin.uni-tuebingen.de/de/…
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On Wednesday we dressed up for our annual #whiteparty with @LabWalz. What a night🥳
Image from Translational Immunology (@Salihlab)
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Interested to work with us as study nurse, technical assistant or research secretary? Check out our open positions: medizin.uni-tuebingen.de/de/… medizin.uni-tuebingen.de/de/… medizin.uni-tuebingen.de/de/…
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It was great fun to do this podcast on #cancer #vaccines @MT_Onkologie
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Short #Article reporting on our CoVaC-1 #COVID19 peptide #vaccine published as @AACR meeting highlight in @VBCancerCare valuebasedcancer.com/issues/…

Peptide-Based CoVac-1 Vaccine Shows Promise Against COVID-19 in Patients with Cancer | Value-Based...

A team of researchers in Germany has developed a multipeptide COVID-19 vaccine that boosts immunity in immunocompromised patients, according to results of a phase 1/2 trial reported at the 2022...

valuebasedcancer.com
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Interesting paper by Kuraoka et al. in @SciImmunology on memory B-cell reactivation by repeated immunizations and the importance of boost #vaccine localization. science.org/doi/10.1126/scii…
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We are looking for a new study nurse. Interested? Find out more details following this link medizin.uni-tuebingen.de/de/…
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Save the date! Join the #livestream of next weeks @Sectio_live episode of our 2 members @JulianeWalz & Ulrich Lauer on #immunotherapy in #cancer. It is part of one of four @civis_eu summer schools at the @MedTuebingen 2022. 📅21 June 🕛2:30pm CEST ℹ️ bit.ly/39lnnlo
Image from Visualizing and Targeting Cancer Stress (@CoE_iFIT)
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Latest german report on our #SARSCoV2 #vaccine, CoVac-1, as possible #Booster and protection for immunodeficient #patients heise.de/hintergrund/Corona-…

Corona-Impfstoff CoVac1: Möglicher Booster und Schutz für Immungeschwächte

Tübinger Forscher testen den Impfstoff CoVac1, der insbesondere T-Zellen ansprechen soll. Im Interview erklärt Oberärztin Juliane Walz, wie gut er wirkt.​

heise.de
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We are looking for new colleagues in different positions: - Lab manager :medizin.uni-tuebingen.de/de/… - Technical assistant: medizin.uni-tuebingen.de/de/… - Secretary: medizin.uni-tuebingen.de/de/…
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New #article reporting on our #tcell activator against #COVID19 EN: gesundheitsindustrie-bw.de/e… DE: gesundheitsindustrie-bw.de/f…

CoVac-1: T-cell activator against COVID-19

Current vaccines against COVID-19 aim at forming neutralising antibodies that prevent the virus from penetrating the host cells. Since people with impaired B-cell immune responses – which can also

gesundheitsindustrie-bw.de
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Our latest publication in Cellular and Molecular Life Sciences: we identified upstream ORFs-derived #peptide as tumor-associated antigens! #immunotherapy #massSpectrometry Great work from our lab member @AnnikaNel in great collaboration with @UK_Muenster link.springer.com/article/10…

Upstream open reading frames regulate translation of cancer-associated transcripts and encode...

Cellular and Molecular Life Sciences - Upstream open reading frames (uORFs) represent translational control elements within eukaryotic transcript leader sequences. Recent data showed that uORFs can...

link.springer.com
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