Drug Hunter • Chemistry PhD • Biotech/Pharma • Scripps Research • Iraqi-Born 🇮🇶 Proud Kiwi 🇳🇿
San Diego, CA
Joined October 2011
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- Following455
- Followers199
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Zaid Amso retweeted
Current therapies for inflammatory bowel disease (IBD) primarily focus on suppressing inflammation. But what if we could repair one of the underlying drivers of disease itself?
Researchers at Calibr-Skaggs are developing CLF065, a potential first-in-class regenerative medicine designed to restore epithelial barrier function—the protective intestinal lining that regulates what passes from the gut into the body. CLF065 is designed with a dual mechanism of action: supporting barrier integrity and stimulating regeneration of the gut lining.
A Phase 2 clinical trial has recently launched in chronic pouchitis, a painful inflammatory condition that can develop in some people with IBD following surgery. In addition, an Investigational New Drug (IND) application has been submitted to support a Phase 2 trial in Crohn's disease.
Learn how regenerative medicine could help shift the treatment paradigm from managing symptoms to repairing the tissue damage at the root of disease.
More: ow.ly/plfR50Zabqq
Nearly every approved IBD therapy suppresses the immune system. CLF065 does something different: regenerative medicine businesswire.com/news/home/2…
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A step forward in our mission of translating scientific discoveries into clinical trials to create impact for patients and value for the institute that supports more drug discovery efforts.
Calibr today announced that @GileadSciences has exercised its option to exclusively license the research institute's NRTTI prodrug, GS-1614.
More at: scripps.edu/news-and-events/…
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Proud to be a member of this talented community
For the last century, institute leaders and renowned scientists have made #ScrippsResearch one of the world’s leading nonprofit biomedical research institutes. Join us as we celebrate our history with stories, events, and memorable moments.
More: ow.ly/B3rz50QolHb
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Zaid Amso retweeted
Today we announce an agreement to acquire RayzeBio, which enhances our increasingly diversified oncology portfolio & represents an opportunity to accelerate development of potential breakthrough medicines for patients. More info & cautionary statements: bit.ly/47lO7u8
Zaid Amso retweeted
RayzeBio sits at the intersection of science and innovation. 🧬
Celebrating their @NasdaqExchange listing at the Closing Bell, $RYZB is an industry-leading pioneer in targeted radiopharmaceutical therapeutics. #NasdaqListed
You were a great mentor and a friend. Big loss to the peptide chemistry community. Godspeed, Dr Waleed Danho @ampepsoc @EurPepSoc dignitymemorial.com/obituari…
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Check out this Postdoctoral Associate, Peptide Chemistry opportunity recruiting2.ultipro.com/SCR1… #peptides #chemistry #research
Science is a collaborative effort! Congratulations to Calibr & Abbvie 🎉
Today Scripps Research’s Calibr & @abbvie announced an expanded collaboration to advance several innovative preclinical & early-stage clinical assets across AbbVie’s core therapeutic growth areas including immunology, oncology, neuroscience & other areas scripps.edu/news-and-events/…
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Zaid Amso retweeted
So many ideas on GLP-1 #obesity Professor Acosta surmises that “We think that some patients have low levels of GLP-1 hormones and that’s why they have obesity. And when you give them the replacement, the GLP-1 analogues, they do extremely well.” @NatureNV nature.com/articles/d41586-0…
Agree 💯
The culture of science has gradually transitioned toward a more executive and results-oriented approach, contributing to a less creative environment for transformative science go.nature.com/3M0hECB
You did it @BrimbleM ! Life-changing medicine for a highly unmet medical need. Big congratulations!
Huge congrats to Distinguished Professor Dame Margaret Brimble @BrimbleM who received the news she's been waiting for, with the FDA approving her drug Trofinetide today. She identified it in a lab @ScienceUoA. Remarkable. bit.ly/3YE6qGr #womeninscience #rettsyndrome
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The NZ Chemistry trio. It was great catching up with Tom Wright & Horace Yeung in Auckland @SCSatUoA @Brimble_Lab @AucklandAlumni
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My 2nd home (2009-2017). Good science, long-lasting friendships, and memories that are cherished forever @AucklandUni @SCSatUoA feeling nostalgic visiting this place after 6 years.
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The TikTok Trend That Triggered a Diabetes Drug Shortage medscape.com/viewarticle/984… via @medscape
Zaid Amso retweeted
A cell going through cell division videoed through a microscope. Chromosomes are shown in pink. @NikonSmallWorld