@ZerneckeLab
 Germany
Joined December 2021
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  • Followers172
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135 Forschende aus der ganzen Welt folgten der Einladung aus Würzburg und trafen sich im Kloster Banz, um sich über die aufstrebende Disziplin #Kardioimmunologie auszutauschen. Details gibt es hier ➡️rb.gy/tchpua @ImmunoCardioLab @sfb1525 @DZHI_Wuerzburg @medeinsUKW
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Alma Zernecke retweeted
Katrin Heinze@HeinzeKatrin2 May 2024
A new piece of translational bioimaging with my great collaborator Erik Henke. ⁦@HeinzeLab⁩ is excited! nature.com/articles/s41467-0…

A vascularized breast cancer spheroid platform for the ranked evaluation of tumor microenvironmen...

Nature Communications - Assessing tumour microenvironment-targeted drug candidates remains challenging. Here, the authors develop a comprehensive screening platform that allows for monitoring,...

nature.com
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Proud to share the second chapter of our joint work on TREM2 - this time in atherosclerosis led by Marie Piollet and @FloPorsch in this fantastic collaboration with the labs of @ClementCochain and @ZerneckeLab.
Nature Cardiovascular Research@NatureCVR12 Mar 2024
Research| Piollet, Porsch, et al. report that the myeloid receptor #TREM2 limits necrotic core formation in #atherosclerosis and controls key atherosclerosis-related functions of macrophages, such as efferocytosis, lipid uptake, and foam cell survival. 👉 rdcu.be/dAY2o
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Integrated single-cell analysis-based classification of #vascular mononuclear phagocytes in mouse & human #atherosclerosis including relevance of study models & refined nomenclature Discover more 👉academic.oup.com/cardiovascr… @ESC_Journals @escardio #CardiovascularResearch
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Excited to share our new paper on the surprising role of complement factor H (CFH) in atherosclerosis published in @ImmunityCP today. In the study led by Máté G. Kiss and Nikolina Papac-Miličević, we identified a subset of macrophages expressing CFH. authors.elsevier.com/a/1hUBd…
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Numerous participants at the two-day symposium of the @EKFStiftung clinician scientist program #TWINSIGHT at the @Uniklinikum_Wue discuss aspects of systems immunology and high throughput technology. #ICSC_Wue
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Breaking ... the macrophage code. Our editorial on the excellent Zernecke-Cochain human-mouse single cell data integration! @ZerneckeLab @ClementCochain @LabMonaco @KirOxford @CVR_TomaszGuzik @ESC_Journals #AtheroVBfanatics academic.oup.com/cardiovascr…

Breaking the macrophage code in atherosclerosis

Modelling human atherosclerosis is challenging. Current murine models of atherosclerosis are monofactorial hyperlipidaemia-based models that are considered

academic.oup.com
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Our freshly printed Clinical Outlook in Nature Reviews in Cardiology on the potential use of scRNAseq for personalized CVD risk prediction. Great times ahead of us! rdcu.be/dcHEV
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Am 29./30. Juni 23 wird Würzburg wieder für alle klinisch & wissenschaftlich Tätigen mit Fokus auf immunologischen Prozessen & Therapien zum place to be. Else Kröner-Forschungskolleg TWINSIGHT lädt zum Translational Immunology – From Target to Therapy VIII ukw.de/aktuelle-meldungen/de…
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📢 We are announcing our Summer School 2023 (July 5-7): Cardio-immune interfaces! ❤️‍🩹 Please register (until May 1) here: cardio-immune-interfaces-sum… We are looking forward to meet you all! 😍 – at Würzburg, Germany
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Happy to share our new study on scRNA-seq analysis of mononuclear phagocytes in mouse and human atherosclerosis, now out in Cardiovascular Research (doi.org/10.1093/cvr/cvac161), led by @ClementCochain in collaboration with @WeinbergerTobi, @AE_Saliba, and others. 1/
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Also, distinct populations of dendritic cells were detected. Based on these findings, we propose an updated scRNA-seq data based classification of mouse aortic mononuclear phagocytes in mouse atherosclerosis. 3/
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We also integrated data from 11 patients and performed cross-species data integration showing conserved features of macrophage and dendritic cell populations in atherosclerosis in mice and humans, important for future experimental investigations and their clinical translation. 4/
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3 days of Cardio-Immune crosstalk are almost over. Great talks today of Burkhard Ludewig and Jürgen Schrader! Thanks to everyone for joining and enjoying! 👏🏻 See you next year! ❤️ @medeinsUKW @DZHI_Wuerzburg @Helmholtz_HIRI @RVZ_Wuerzburg @KantonsspitalSG @UniklinikDUS – at Bad Staffelstein, Deutschland
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Translational Immunology – From Target to Therapy VII Das int. Symposium des Else Kröner #Forschungskollegs #TWINSIGHT mit Schwerpunkt Systemimmunologie und Hochdurchsatztechnologien findet am 14./15. Juli im Juliusspital/Würzburg statt. @Uniklinikum_Wue ow.ly/WkIJ50JOuOf
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Alma Zernecke retweeted
DZHK Germany@dzhk_germany30 May 2022
Replying to @InstCardReg_FFM @AndreasZeiher @YoungDZHK @DimmelerLab
Good to know 💡: From now on, the Science on Friday webinars are also open to non-DZHK members. If you want to be added to our invitation list, please send an email to [email protected].
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Forschungskolleg TWINSIGHT @izkf_wuerzburg mit Schwerpunkt Systemimmunologie und Hochdurchsatztechnologien lädt am 14./15. Juli 2022 alle Interessierten zum internationalen Else Kröner-Symposium im Würzburger Juliusspital ein. med.uni-wuerzburg.de/izkf/in…
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Happy to share our recent review. Hope that the links to publicly avalaible data from cardiovascular tissues, disease models and human samples may be helpful for your own research! #singlecell #CVdisease
Institute of CVR@InstCardReg_FFM11 Mar 2022
Great new review published today in European Heart Journal @escardio on how to use single-cell technologies to decipher cardiovascular diseases by @WesleyAbplanalp @StefanieDimmel1 and @NR_Tucker Check it out --> bit.ly/3hWSl3W #singlecell #CVdisease #science
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Outstanding Cardio-immunology meeting, excellent program!
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