Compressing biology to develop the next generation of therapeutics

Seattle, WA
Joined October 2023
Congratulations to Dr. David Baker on the Nobel Prize in Chemistry! We are proud to celebrate Dr. Baker’s groundbreaking contributions to protein design, which have transformed modern medicine. youtube.com/watch?v=6-A4dUow…
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Dr. Baker was the mentor and doctoral supervisor of our CTO, @Arielbs100. Our work continues to be deeply influenced by Dr. Baker’s vision, driving us to push the boundaries of protein design to tackle some of the most complex challenges in medicine.
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We are excited to contribute to the scientific revolution Dr. Baker has helped shape and look forward to advancing the future of drug development.
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Founded by @roee_farber, @Arielbs100, @ozelichov and Ori Hassin our COMPACT platform compresses complex biological structures into smaller, more efficient de novo-designed proteins that retain full functionality, optimizing delivery and therapeutic effectiveness.
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We're backed by NFX and MoreVC and are expanding our team in Seattle, Boston and Tel Aviv.
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Here's an interesting use of AI in drug design: making compact proteins. @ZipBio_Inc is shaving off the unimportant parts of proteins and using generative AI to fill in a backbone that holds the molecule together. Read more in my exclusive for @endpts: endpts.com/exclusive-zipbio-…
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The February issue, with a focus on protein engineering, is live nature.com/nbt/volumes/42/is… Our cover shows the three data types key to machine learning for functional protein design: structure, sequence and labels, from a Review by Notin et al. go.nature.com/49EPi9x
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A new paper by our co-founder and CTO @Arielbs100 is now out in @CellCellPress
It's so satisfying to see our work in print! We showcase computer designed #protein #biomaterials engaging cells with molecular precision to decipher one of the most fundamental and yet elusive determinants of cell division process. Huge POC for the future of #synthetic_biology!
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