Alex Powers (@_Alex_Powers_) profile picture

Alex Powers

@_Alex_Powers_

PhD candidate in @cohenlaboratory at @UNC_SOM

 Chapel Hill, NC
Joined November 2020
  • Tweets8
  • Following25
  • Followers24
It was so cool to see Cohen lab members’ images on the @zeiss_micro WOW Wall at #cellbio2023! Go @MC_Zanellati and @ChihHsuanHsu1
Image from Sarah Cohen (@cohenlaboratory)
Image from Sarah Cohen (@cohenlaboratory)
3
8
123
7,751
Alex Powers retweeted
Alzforum (@alzforum) profile picture
Alzforum@alzforum6 Sep 2023
Reacting to Aβ fibrils, microglia hoard lipid droplets, as do microglia around amyloid plaques in #Alzheimersdisease. Two enzymes that make triglycerides are to blame. @LifeAtPurdue @ClevelandClinic @Stanford ow.ly/VvAm50PIuVZ
Image from Alzforum (@alzforum)
19
3
72
15,479
Alex Powers retweeted
Alzforum (@alzforum) profile picture
Alzforum@alzforum23 Aug 2023
Switching astrocytes from expressing APOE4 to APOE2 reduced plaques, gliosis, and bettered memory in a mouse amyloidosis model. This may help guide APOE replacement therapies. #AAIC2023 ow.ly/7yfZ50PCzB9
Image from Alzforum (@alzforum)
1
19
2
86
17,603
I am thrilled to see Greg Miner and team’s work on the role of PLIN5-FATP4 membrane contact sites in #LipidDroplet to #Mitochondria fatty acid transport published today in @Dev_Cell: authors.elsevier.com/a/1hCz%… 1/5
Sarah Cohen (@cohenlaboratory) profile pictureSarah Cohen@cohenlaboratory4 Feb 2022
I am so excited to share my lab’s first preprint! Led by Greg Miner, we take a dive into the function of #LipidDroplet-#mitochondria contact sites: 1/11 biorxiv.org/content/10.1101/…
Perilipin 5 interacts with Fatp4 at membrane contact sites to promote lipid droplet-to-mitochondria...

Perilipin 5 interacts with Fatp4 at membrane contact sites to promote lipid droplet-to-mitochondria...

Cells adjust their metabolism by remodeling membrane contact sites that channel metabolites to different fates. Lipid droplet (LD)-mitochondria contacts change in response to fasting, cold exposure,...

biorxiv.org
19
27
3
141
26,084
New preprint from the Cohen lab! Led by @iawindham, we found that astrocyte #APOE can traffic to #LipidDroplets, where it modulates LD composition and size: biorxiv.org/content/10.1101/… 1/12
APOE traffics to astrocyte lipid droplets and modulates triglyceride saturation and droplet size

APOE traffics to astrocyte lipid droplets and modulates triglyceride saturation and droplet size

The E4 variant of APOE strongly predisposes individuals to late-onset Alzheimer’s disease. We demonstrate that in response to neutral lipid synthesis, apolipoprotein E (APOE) in astrocytes can avoid...

biorxiv.org
14
58
11
254
88,204
Please spread the word: we're hiring! We're recruiting a research technician to join our team and study astrocyte cell biology in the supportive environment of the UNC Neuroscience Center. See the job posting for more details: unc.peopleadmin.com/postings…
17
1
23
7,211
I am so excited to share my lab’s first preprint! Led by Greg Miner, we take a dive into the function of #LipidDroplet-#mitochondria contact sites: 1/11 biorxiv.org/content/10.1101/…
Perilipin 5 interacts with Fatp4 at membrane contact sites to promote lipid droplet-to-mitochondria...

Perilipin 5 interacts with Fatp4 at membrane contact sites to promote lipid droplet-to-mitochondria...

Cells adjust their metabolism by remodeling membrane contact sites that channel metabolites to different fates. Lipid droplet (LD)-mitochondria contacts change in response to fasting, cold exposure,...

biorxiv.org
21
55
11
332
Alex Powers retweeted
UF Medicine (@UFMedicine) profile picture
UF Medicine@UFMedicine3 Mar 2021
Mavis Agbandje-McKenna, Ph.D., a @UFHealth biochemistry researcher whose widely recognized work with viruses led to treatment advances, has passed away at age 57. bit.ly/3uS4Piv
1
19
16
54
Load more