Jana Biermann, Ph.D. (@_janabiermann) profile picture

Jana Biermann, Ph.D.

@_janabiermann

Postdoc at Columbia University | Cancer genomics | Single cell sequencing | Computational biology 🧬

 New York, NY
orcid.org/0000-0002-8907-4633
Joined January 2019
  • Tweets67
  • Following179
  • Followers124
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Photo by Jana Biermann, Ph.D. (@_janabiermann)Photo by Jana Biermann, Ph.D. (@_janabiermann)
Excited to see our #Melanoma #BrainMetastasis Atlas published in @CellCellPress. Comparison of brain and extracranial metastases revealed adoption of neuronal programs and increased #chromosomal_instability in cancer cells in the brain. @BizarMd @JCA_Melms cell.com/cell/fulltext/S0092…
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Johannes Melms (@JCA_Melms) profile picture
Johannes Melms@JCA_Melms23 Feb 2023
Thank you very much @JRNLclub for the opportunity to present our work on treatment-naive melanoma brain metastases. Work done at the @BizarMd lab at @Columbia together with my colleague @_janabiermann and amazing collaborators.
JRNLclub (@JRNLclub) profile pictureJRNLclub@JRNLclub21 Feb 2023
.@JCA_Melms discusses the treatment-naive ecosystem of human melanoma brain metastasis and presents how these differ from extra-cranial metastases. @CellCellPress @_janabiermann @BizarMD @ColumbiaCancer @ColumbiaMed #JRNLclub jrnlclub.org/research-films/…
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JRNLclub (@JRNLclub) profile picture
JRNLclub@JRNLclub21 Feb 2023
.@JCA_Melms discusses the treatment-naive ecosystem of human melanoma brain metastasis and presents how these differ from extra-cranial metastases. @CellCellPress @_janabiermann @BizarMD @ColumbiaCancer @ColumbiaMed #JRNLclub jrnlclub.org/research-films/…
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Johannes Melms (@JCA_Melms) profile picture
Johannes Melms@JCA_Melms10 Jan 2023
Excited to share our paper from @BizarMd and @elhamazizi labs at @Columbia just out in @NatureGenet. Thank you for the great collaboration Yiping Wang and @joy_lfan and fantastic leadership and mentorship by Ben and Elham!
Nature Genetics (@NatureGenet) profile pictureNature Genetics@NatureGenet9 Jan 2023
‼️ JUST PUBLISHED @NatureGenet 📰 Multimodal single-cell and whole-genome sequencing of small, frozen clinical specimens 🧑🏿‍🤝‍🧑🏿 @elhamazizi Ben Izar and team 👇🏼 go.nature.com/3VZKkwy
Multimodal single-cell and whole-genome sequencing of small, frozen clinical specimens

Multimodal single-cell and whole-genome sequencing of small, frozen clinical specimens

Nature Genetics - High-quality multimodal single-cell, bulk and spatial genomics data are prepared from low-input, frozen needle biopsy specimens collected during routine clinical procedures.

nature.com
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Elham Azizi (@elhamazizi) profile picture
Elham Azizi@elhamazizi9 Jan 2023
Our first (of many to come😃) exciting collaborative effort(s) with the @BizarMd Lab, led by superstars Yiping Wang @joy_lfan @JCA_Melms bringing multimodal single-nucleus RNA/TCR, spatial and whole-genome seq to the #clinical arena! #cancergenomics #computationalbiology
Nature Genetics (@NatureGenet) profile pictureNature Genetics@NatureGenet9 Jan 2023
‼️ JUST PUBLISHED @NatureGenet 📰 Multimodal single-cell and whole-genome sequencing of small, frozen clinical specimens 🧑🏿‍🤝‍🧑🏿 @elhamazizi Ben Izar and team 👇🏼 go.nature.com/3VZKkwy
Multimodal single-cell and whole-genome sequencing of small, frozen clinical specimens

Multimodal single-cell and whole-genome sequencing of small, frozen clinical specimens

Nature Genetics - High-quality multimodal single-cell, bulk and spatial genomics data are prepared from low-input, frozen needle biopsy specimens collected during routine clinical procedures.

nature.com
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Jana Biermann, Ph.D. retweeted
Nature Genetics (@NatureGenet) profile picture
Nature Genetics@NatureGenet9 Jan 2023
‼️ JUST PUBLISHED @NatureGenet 📰 Multimodal single-cell and whole-genome sequencing of small, frozen clinical specimens 🧑🏿‍🤝‍🧑🏿 @elhamazizi Ben Izar and team 👇🏼 go.nature.com/3VZKkwy
Multimodal single-cell and whole-genome sequencing of small, frozen clinical specimens

Multimodal single-cell and whole-genome sequencing of small, frozen clinical specimens

Nature Genetics - High-quality multimodal single-cell, bulk and spatial genomics data are prepared from low-input, frozen needle biopsy specimens collected during routine clinical procedures.

nature.com
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Elham Azizi (@elhamazizi) profile picture
Elham Azizi@elhamazizi25 Nov 2022
We are thrilled to share #Starfysh ⭐️ an auxiliary deep generative model for multi-modal analysis and integration of spatial transcriptomic (ST) datasets and histology images, and its application to heterogeneous #breastcancer tumors! 😃 tinyurl.com/hffdhvx7 1/
Image from Elham Azizi (@elhamazizi)
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Tricia Ho (@triciahoho) profile picture
Tricia Ho@triciahoho18 Oct 2022
Grateful to be given the opportunity to present virtually this morning (extra early, NYC time!) at the @SocietyMelanoma #2022congress taking place in Edinburgh! Wish I could be there in person, and thanks as always to @BizarMd and labmates @meri_rogava and @JCA_Melms #smr2022
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MarineLab (@lab_marine) profile picture
MarineLab@lab_marine21 Sep 2022
Check out our paper just published in @nature showing that melanoma growth and metastatic dissemination are fuelled by limited and distinct cancer cell populations. nature.com/articles/s41586-0… work led by AMAZING @karraspan (1/3)
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CU Postdoc Society (@CUPostdocs) profile picture
CU Postdoc Society@CUPostdocs19 Aug 2022
Jana Biermann, a postdoc at Columbia University discovered that metastatic cancer cells have unstable DNA which helps them to evade the body's immune system. Read more about this discovery in this week’s CUPS Press Office release: tinyurl.com/ys3c23ad blogs.cuit.columbia.edu/post…
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Columbia Cancer researchers, led by Ben Izar, MD, PhD, have completed one of the most comprehensive studies of the cells inside melanoma brain metastases, uncovering details that could spur the development of a new generation of therapies. Explore here: cuimc.columbia.edu/news/new-…
Image from Herbert Irving Comprehensive Cancer Center (@columbiacancer)
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Cell (@CellCellPress) profile picture
Cell@CellCellPress11 Jul 2022
In the latest issue! Dissecting the treatment-naive ecosystem of human melanoma brain metastasis dlvr.it/STjxfg
Dissecting the treatment-naive ecosystem of human melanoma brain metastasis

Dissecting the treatment-naive ecosystem of human melanoma brain metastasis

Multi-modal single-cell analysis reveals genomic, transcriptional, and tumor-microenvironmental features of treatment-naive human melanoma brain metastases compared with extracranial metastases.

cell.com
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Meri Rogava (@meri_rogava) profile picture
Meri Rogava@meri_rogava8 Jul 2022
Very happy to share our recent work on melanoma brain metastasis.. 🧠 so happy and proud to be part of this amazing team and have been given an opportunity to contribute to this nice piece of work! Huge congrats to @_janabiermann @JCA_Melms and @BizarMd and TEAM 💫💫💫
bizarMD (@BizarMd) profile picturebizarMD@BizarMd7 Jul 2022
Excited to see our study on melanoma brain metastasis (MBM) published in @CellCellPress today. A massive team effort led by @_janabiermann and @JCA_Melms supported by many, outstanding collaborators. cell.com/cell/fulltext/S0092…
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Denis (@DenisSchapiro) profile picture
Denis@DenisSchapiro7 Jul 2022
Congratulations to @_janabiermann @JCA_Melms @BizarMd and team. Very happy that we could contribute with image analysis lead by @miguelib93 @flowuenne and Margot Chazotte. Read below to learn more about what unique features melanoma cells have to acquire to metastasize to the🧠
bizarMD (@BizarMd) profile picturebizarMD@BizarMd7 Jul 2022
Excited to see our study on melanoma brain metastasis (MBM) published in @CellCellPress today. A massive team effort led by @_janabiermann and @JCA_Melms supported by many, outstanding collaborators. cell.com/cell/fulltext/S0092…
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Johannes Melms (@JCA_Melms) profile picture
Johannes Melms@JCA_Melms7 Jul 2022
Excited to share our new study on the ecosystem of treatment-naïve melanoma brain metastasis (MBM) published in @CellCellPress today. A team effort from the Izar lab with @BizarMD @_janabiermann and many collaborators. cell.com/cell/fulltext/S0092…
Image from Johannes Melms (@JCA_Melms)
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bizarMD (@BizarMd) profile picture
bizarMD@BizarMd7 Jul 2022
Excited to see our study on melanoma brain metastasis (MBM) published in @CellCellPress today. A massive team effort led by @_janabiermann and @JCA_Melms supported by many, outstanding collaborators. cell.com/cell/fulltext/S0092…
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somnath tagore (@SomnathTagore) profile picture
somnath tagore@SomnathTagore7 Jul 2022
Our study “Dissecting the treatment-naive ecosystem of human melanoma brain metastasis” was published today in @CellCellPress cell.com/cell/fulltext/S0092… @_janabiermann @JCA_Melms @BizarMd
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bizarMD (@BizarMd) profile picture
bizarMD@BizarMd4 May 2022
Very helpful method for analysis of single-cell RNA-seq data of tumor samples. By the one and only @SomnathTagore biorxiv.org/content/10.1101/…
KINOMO: A non-negative matrix factorization framework for recovering intra- and inter-tumoral...

KINOMO: A non-negative matrix factorization framework for recovering intra- and inter-tumoral...

Single-cell RNA-sequencing (scRNA-seq) is a powerful technology to uncover cellular heterogeneity in tumor ecosystems. Due to differences in underlying gene load, direct comparison between patient...

biorxiv.org
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Johannes Melms (@JCA_Melms) profile picture
Johannes Melms@JCA_Melms11 Apr 2022
Delighted to show our work on melanoma brain metastasis with @_janabiermann and @BizarMd at #AACR2022 today. Poster 984 on board 13/13 from 9-12AM. Come by and have a chat.
Image from Johannes Melms (@JCA_Melms)
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bizarMD (@BizarMd) profile picture
bizarMD@BizarMd23 Mar 2022
Very excited to share new work from the lab dissecting mechanisms of cancer immune evasion. True team effort led by MD/PhD student @triciahoho and post-docs @JCA_Melms @meri_rogava 1/14 biorxiv.org/content/10.1101/…
The CD58:CD2 axis is co-regulated with PD-L1 via CMTM6 and governs anti-tumor immunity

The CD58:CD2 axis is co-regulated with PD-L1 via CMTM6 and governs anti-tumor immunity

The cell autonomous balance of immune-inhibitory and -stimulatory signals is a critical yet poorly understood process in cancer immune evasion. Using patient-derived co-culture models and humanized...

biorxiv.org
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