Ahuja Lab (@ahuja_77) profile picture

Ahuja Lab

@ahuja_77

Decoding🥼 Biochemical🧬🧪 mysteries using ChemInformatics 👨‍💻 ¶Assoc. Prof #IIIT-D 🇮🇳| #Prev #UniOfCologne🇩🇪| #MaxPlanckAging🇩🇪| #LKCSingapore 🇸🇬|

 New Delhi, India
ahuja-lab.in
Joined August 2016
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A preprint annotating the lipoprotein lipase as a cholesterol ester hydrolase is now online. Excellent work by @aakash0308 from our lab @IISERPune biorxiv.org/content/10.64898…
The Hunt for Cholesteryl Ester Hydrolases: Identification of Lipoprotein Lipase as a Cholesteryle...

The Hunt for Cholesteryl Ester Hydrolases: Identification of Lipoprotein Lipase as a Cholesteryle...

Cholesteryl esters (CEs) are central intermediates in cholesterol storage and transport, yet the enzymes responsible for their hydrolysis in mammals remain poorly defined. While lysosomal acid lipase...

biorxiv.org
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#ChemMethods #OnTheCover Mechanism-Aware #DeepLearning Maps the Redox Landscape of Cancer-Relevant Antioxidants (Chem. Methods 5/2026) (Gaurav Ahuja and co-workers) @SatijaShiva @SaveenaSolanki @ahuja_77 doi.org/10.1002/cmtd.70120
Front Cover: Mechanism‐Aware Deep Learning Maps the Redox Landscape of Cancer‐Relevant Antioxidants...

Front Cover: Mechanism‐Aware Deep Learning Maps the Redox Landscape of Cancer‐Relevant Antioxidants...

The Front Cover illustrates a mechanism-informed hierarchical multitask learning (MI-HMTL) framework that maps the complex redox landscape. The central mitochondrion and chemical structures symboli...

chemistry-europe.onlinelibrary.wiley.com
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Ahuja Lab retweeted
Sanjeev Varshney (@skvdst) profile picture
Sanjeev Varshney@skvdstMar 3
Replying to @HFSP
@HFSP - Research Grant and Early Career Supports projects in basic research studying fundamental problems in the life sciences. Research topics may include biological functions at all levels of analysis. Details at dbt.gov.in/storage/media/3qr… Submit LOI by 17th March 2026
Image from Sanjeev Varshney (@skvdst)
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Feeling Proud. Congratulations once again @lab_sengupta
Debarka Sengupta (@lab_sengupta) profile pictureDebarka Sengupta@lab_sengupta23 Dec 2025
Received the Rashtriya Vigyan Puraskar today from the Honorable President of India.
Image from Debarka Sengupta (@lab_sengupta)
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Our lab is thrilled to introduce Chemical Dice Integrator (CDI), a groundbreaking framework that fuses SIX different "lenses" on molecular data into one unified, super-powered representation. Link: doi.org/10.1101/2025.11.11.6… @IIITDelhi
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🚨 New Preprint! 🚨 MutAIverse: an AI-driven DNA adductomics platform that builds a comprehensive adduct library, retro-tracks genotoxins & detects known + novel adducts in patient biopsies. A leap in decoding mutational footprints. Link: biorxiv.org/content/10.1101/… @IIITDelhi
MutAIverse: An AI-Powered, Mechanism-backed Platform for Discovering Novel DNA Adducts and their...

MutAIverse: An AI-Powered, Mechanism-backed Platform for Discovering Novel DNA Adducts and their...

Genotoxin exposure leads to DNA adduct formation, potentially causing mutations if unrepaired. Current DNA adductomics platforms or analytical workflows are limited by incomplete spectral libraries,...

biorxiv.org
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Interested in inferring Aging-associated Bioactivity from Cellular Imaging? Then this protocol is best to follow. For more details about the protocol, refer to lnkd.in/gyibKTtv. Great efforts from @SubhadeepDuari #VishakhaGautum, the two-star graduate students. @IIITDelhi
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Image from Santosh Chauhan (@Chauhanlab_ILS)
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scCamAge: A context-aware prediction engine for cellular age, aging-associated bioactivities, and morphometrics dlvr.it/THrNtj

scCamAge: A context-aware prediction engine for cellular age, aging-associated bioactivities, and...

Gautam, Duari et al. developed scCamAge, an AI tool for predicting cell age and age-related bioactivities from micrographs. scCamAge uses the joint representation of image features, cell-shape...

cell.com
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🚀 Exciting News! Our New Publication on scCamAge is Out in @CellReports! 🎉. Thanks @IIITDelhi ✨ Key Findings: ✅ Trained on ~1 million yeast cells & validated with pro-longevity drugs, genetic mutants, and stress models. 🔥 Predicted pro-longevity responses under thermal
Image from Ahuja Lab (@ahuja_77)
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stress, confirmed via integrative omics. 🧑‍⚕️ Outperformed generic models in predicting chemical & replication-induced senescence in human fibroblasts, despite being trained only on yeast! 🔄 Further enhanced by retraining on human fibroblast senescence datasets, improving
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It's ability to detect senescent cells. 🔗 Read more: lnkd.in/g8nmca65 #scCamAge #AgingBiology #DeepLearning #SingleCell #YeastAging #Senescence #iiitdelhi Indraprastha Institute of Information Technology, Delhi CAI IIITD
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This time @ccmb_csir ....Again it's time, for the gang to meet. Lots of Science and lots of 😎. @sriram_varahan @Banerjeeiitb @MahakSharma23 @amit_tuli @benubrata @ahuja_77 @indranilb4u @Sci_Lipi @NitinRammohan @tamminenilab @MotianiRaj1 @RaviManjithaya @RohanKhadilkarr
Image from Autophagy India Network (AIN) (@Autophagy_India)
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#authorinterview: @sakshi_327, PhD candidate with @ahuja_77 at @IIITDelhi, discusses 'AgeXtend,' a multimodal AI-based geropredictor published in @NatureAging. This innovation merges biotech & AI to explore aging science. #AI #AgingResearch biopatrika.com/academia/rese…
Researchers at IIIT-Delhi develop a multimodal AI-based geropredictor - AgeXtend | BioPatrika

Researchers at IIIT-Delhi develop a multimodal AI-based geropredictor - AgeXtend | BioPatrika

AgeXtend is a multimodal, mechanism-backed, AI-based platform that predicts the anti-aging potential of a compound.

biopatrika.com
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Applications open for 6-week undergraduate summer training program 2025 at Param Hansa Center for Computational Oncology, @iiscbangalore. Deadline: Jan 31, 2025. forms.gle/XcdsGXrpsAdMc6xk8 @biopatrika @IndiaBioscience @DynamicsLiving @SMBMathOnco @BE_IISc @cphms_aic @rakeshthejoy
Image from Mohit Kumar Jolly (@mkjolly15)
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🤖 Scientists at @IIITDelhi have created AgeXtend, an AI platform to discover geroprotectors—compounds that slow down ageing. ⚡ AgeXtend screens 1.1 billion molecules, predict toxicity, and pinpoint how they work. go.nature.com/4iUEslc #NatureIndia #AI @ahuja_77

AI screens over 1 billion compounds to uncover new anti-ageing candidates

Nature India - Explainable platform enables large-scale, rapid screening

nature.com
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Thank you @arshukla for the encouraging words🙏
Arun K. Shukla (@arshukla) profile pictureArun K. Shukla@arshukla23 Dec 2024
I haven't been to this 👇place yet in person, but their faculty expertise, research program, and publication outcomes are truly very impressive! cb.iiitd.ac.in/final-index.p… The latest is this wonderful piece of work from @ahuja_77 et al., in @NatureAging nature.com/articles/s43587-0…
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Extremely delighted to share our recent publication showing how peroxisomes help in inter-organellar cholesterol transport! Now in EMBO Reports! @CSIR_CDRI @AcSIR_India @India_Alliance Great partnership @ammanathan @DipaLab_IISc embopress.org/doi/full/10.10…?
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Ahuja Lab retweeted
EMBO (@EMBO) profile picture
EMBO@EMBO3 Dec 2024
27 life scientists have been selected as the newest members of the EMBO Young Investigator Programme. Congratulations and welcome! Read more: embo.org/press-releases/twen…
Twenty-seven scientists become EMBO Young Investigators – Press releases – EMBO

Twenty-seven scientists become EMBO Young Investigators – Press releases – EMBO

The group leaders join an international network of nearly 800 life scientists and receive financial support

embo.org
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Online now!✨RESEARCH: @sakshi_327 @AayushiMittal16 et al present AgeXtend, an AI platform to predict geroprotectors, tested in yeast, worms and senescence assays @ahuja_77 @CompBio_IIITD @IIITDelhi nature.com/articles/s43587-0… rdcu.be/d2g2z
Discovering geroprotectors through the explainable artificial intelligence-based platform AgeXtend

Discovering geroprotectors through the explainable artificial intelligence-based platform AgeXtend

Nature Aging - Arora et al. present AgeXtend, an explainable artificial intelligence-based platform that leverages bioactivity data to predict geroprotectors. They validate potential geroprotectors...

nature.com
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