MD/PhD - 🔬Pathologist & Max-Eder Research Group Leader in Clinical Multi-Omics

Munich, Germany
Joined July 2016
Andreas Mock retweeted
1/7🎉 Introducing Phoenix: generative AI predicting spatially resolved gene expression from routine H&E slides-enabling virtual spatial-omics. Zero-shot. Across cancers, organs & species. Huge thanks to my co-first @TranManuel & all collaborators! 🙌 📜: doi.org/10.64898/2026.04.25.…
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Andreas Mock retweeted
Neue Publikation des DKFZ/NCT/DKTK MASTER-Programm: Handbuch zur Nutzung von Genomdaten i. d. Präzisionsonkologie. Handbuch soll Ärzt:innen, Biolog:innen und Bioinformatiker:innen bei der klinischen Interpretation genomweiter molekularer Informationen unterstützen.
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Clinical Multiomics for #PrecisionOncology - It’s exciting to reflect about its utility today and the prospect it holds. Let’s bring it to even more patients in the near future!
Please read our new paper, published today with @SpringerNature in @Nature_NPJ, on the practical approach at @NCT_HD and @NCT_UCC_DD to clinical decision-making in molecular tumor boards based on genome/exome, transcriptome, and methylome data: rdcu.be/dpwCy
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Andreas Mock retweeted
Transcriptome profiling for precision cancer medicine using shallow nanopore cDNA sequencing Great study from ⁦@DKFZ⁩ ⁦@am0ck⁩ on shallow #nanopore RNA sequencing for transcriptome profiling of human cancers. ⁦@SciReports⁩ #cancer nature.com/articles/s41598-0…
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Looking forward to discuss the next frontiers of molecular diagnostics at Precision Oncology Forum in Berlin 6-7 Dec ’22 @precisionforum #OncologyForum
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In Annals of Oncology, results from the German 🇩🇪 #PrecisionMedicine 🧬🎯💊 NCT/DKTK MASTER trial inform on the association of cancer perdisposing genes and rare cancer annalsofoncology.org/article…
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Great teamwork out in @NatureComms - deep dive into the the mol landscape of #cancer of unknown primary out of @DKTK_ MASTER. ✅70 #patients ➡️56 MTB reccomendations 🎯20/56 treated @OncoAlert 🚨#PrecisionMedicine @StefanFrohling @ChrisHeining @am0ck nature.com/articles/s41467-0… – at Munich, Germany
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Andreas Mock retweeted
Our latest work is now online as a preprint in #bioRxiv. I had the honor to work with @am0ck, Melissa Braun, @claudia_scholl and @StefanFrohling at @DKFZ and @NCT_HD. We used Oxford @nanopore sequencing to get a glimpse of the transcriptomes of tumor samples, which were 1/8
Shallow nanopore RNA sequencing enables transcriptome profiling for precision cancer medicine biorxiv.org/cgi/content/shor… #bioRxiv
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Happy to join Frederick Klauschen @LMU_Muenchen Pathology as an Oncology-trained Pathologist. Looking forward to combine Computational & Molecular Pathology to develop the next generation of biomarkers for #PrecisionOncology with @BenWestphalen and team @CccLmu.
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Our new paper is out now 🔥🔥🔥 FDA-approved multi-receptor tyrosine kinase inhibitor PONATINIB is highly effective in preclinical #meningioma models! @MDPIOpenAccess @Cancers_MDPI @uniklinik_hd mdpi.com/2072-6694/13/23/589…
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Fantastic #PrecisionMedicine effort by @mpmnedumudy and @Elkabetslab for patients with #headandneckcancer. Perfect example that we need to better understand the impact of targeted therapies on the tumor immune microenvironment.
Replying to @Elkabetslab
@mpmnedumudy showed that the #MAPK pathway is hyperactive in #headandneckcancer (HNC) and is associate with poor prognosis (collaboration Hess @am0ck @DKFZ @HeidelbergU. Treatment of mice with trametinib, an MEK1/2 inhibitor, induced a delay in HNC initiation and progression.
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Wir freuen uns, dass das @Dt_Aerzteblatt auf unsere Arbeit aufmerksam macht, die hoffentlich dazu beiträgt, seltene Krebserkrankungen besser zu verstehen, präziser zu diagnostizieren und wirksamer zu behandeln. @NCT_HD @DKFZ @DKTK_ @uniklinik_hd
Patienten mit seltenen Krebserkrankungen profitieren von molekularer Analyse: Heidelberg – Patienten mit seltenen Tumorerkrankungen profitieren von einer umfassenden molekularen Analyse des… dlvr.it/S4yMbg #Studie #selteneKrebserkrankungen #Analyse #NCT #DKFZ
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My new lab @DKFZ is recruiting! 2 experimental postdocs in spatial genomics and single cell mutagenesis + 1 research technician post to fill. Join us in beautiful Heidelberg. Please RT jobs.dkfz.de/en/jobs/83466/p… jobs.dkfz.de/en/jobs/83473/p… jobs.dkfz.de/en/jobs/83471/r…
We are excited to see this work published and hope it will help improve our understanding and clinical management of #RareCancers such as bone and soft-tissue #Sarcoma. Please get in touch if you are interested in collaborating with us!
Online now in @CD_AACR: Comprehensive Genomic and Transcriptomic Analysis for Guiding Therapeutic Decisions in Patients with #RareCancers (from the @DKTK_ MASTER Program) @StefanFrohling @DKFZ @NCT_HD @TMO_Heidelberg @uniklinik_hd @NCT_UCC_DD cancerdiscovery.aacrjournals…
Online now in @CD_AACR: Comprehensive Genomic and Transcriptomic Analysis for Guiding Therapeutic Decisions in Patients with #RareCancers (from the @DKTK_ MASTER Program) @StefanFrohling @DKFZ @NCT_HD @TMO_Heidelberg @uniklinik_hd @NCT_UCC_DD cancerdiscovery.aacrjournals…
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Please read our new paper on the use of whole-genome/exome and RNA sequencing for therapeutic decision-making in patients with rare cancers within the MASTER program of the German Cancer Consortium (DKTK). cancerdiscovery.aacrjournals…
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