@anotherJohnMac

enzyme enthusiast

Joined March 2022
  • Tweets5
  • Following42
  • Followers87
John McIntosh retweeted
Rebecca Ruck@Ruck_chem6 Jul 2022
#MerckChemistry is seeking a new Director to lead our legendary #Catalysis & #LabeledCompoundSynthesis groups as part of our cross-modality #EnablingTechnologies team. Apply here! #ChemJobs msd.wd5.myworkdayjobs.com/Se…
19
1
41
John McIntosh retweeted
Ania Fryszkowska@fryania16 Jun 2022
We keep on asking, #enzymes keep on giving! we asked an acylase to recognize 3 different amines on insulin and today we can share new strategy for enzymatic functionalization of native proteins #directedevolution #bioconjugation #merckchemistry science.org/doi/10.1126/scie…

A chemoenzymatic strategy for site-selective functionalization of native peptides and proteins

Selective enzymatic modification of native proteins enables efficient synthesis of insulin therapeutics.

science.org
4
53
2
276
John McIntosh retweeted
Ania Fryszkowska@fryania17 Jun 2022
Great to see our work highlighted @cenmag : Evolved enzymes help modify insulin cen.acs.org/biological-chemi… @beth_halford

Evolved enzymes help modify insulin’s amines

Strategy could precisely tweak protein drugs to improve their pharmacology

cen.acs.org
1
5
47
John McIntosh retweeted
Hans Renata@hanzyduzit20 May 2022
I will be moving my lab to @RiceUniversity this fall as a CPRIT scholar. Grateful for my time at Scripps and excited for what the future holds at Rice chemistry, bioscience and bioengineering, and future collaboration opportunities with the Texas Medical Center. LFG.
18
12
515
Excited to share our work developing an enzymatic cascade to MK-1454. Really fun getting to work with so many great people on this project. @nastaran198 @jobligac @patrickfier @synbiogrant @DrLCsquare @ruck_chem @matthewmaddess #merckchemistry nature.com/articles/s41586-0…
8
32
10
147
Load more