The NHS specifically advises AGAINST sponging or ANY physical cooling measures for fever It does NOT bring core temperature down, and only serves to make the patient LESS COMFORTABLE by increasing their bodies efforts to keep their temperature elevated nhs.uk/symptoms/fever-in-chi…

FYI the presentation is online, has some more info! They don't use flat priors, they use weak neutral priors Adjustment is for baseline variables, there is info borrowing from other arms but the effect did not change (only the power) criticalcarereviews.com/meet…

Join me to learn how oseltamivir for flu and adjunctive clindamycin for Staph aureus have likely been killing patients - despite their inclusion in many guidelines If you find it useful please share and subscribe open.substack.com/pub/alasda…

My new post looks at two routinely used antimicrobials In the last few weeks both have shown to be ineffective - and worse - highly likely to have caused harm, including death When we give treatments without RCT evidence, we risk killing patients (link below)

Decided to start taking things more seriously over at S*bst@ck and write more often Great to have people engage with the work!

Join me for the latest updates on the Ebola outbreak Case numbers, misinformation (some from actual "experts"), potential therapeutics in the pipelines, and what this all means with me here If you find it useful please subscribe and share alasdairmunro.substack.com/p…

The Ebola outbreak has been extremely fast moving, and the news has been mostly terrible News of potential trials of vaccines and therapeutics does lend some hope - but these are some way off Catch up on the latest developments with me here (link in reply 👇)

My framework for - how to determine how much evidence is enough - how to prevent arguing about science and certainty, when you're really arguing about decision thresholds and values One of the most common errors during the pandemic alasdairmunro.substack.com/p…

I've written about how we determine how much evidence we need to answer a question It's possible to weaponise a lack of evidence OR urgency to act to get the outcome you want - and we still see it happen often So how do we know what to do? Link in next post 👇