@as_bates

#neuroscience #connectomics @harvardmed w/ @RachelIreneWils. Past: @MRC_LMB, @CamZoology, @flyconnectome. Distant past: @uclnpp. https://xitter.cf/t.co/0eZdKDZGsb

 Cambridge, England
Joined July 2016
  • Tweets586
  • Following721
  • Followers750
89Media
Alexander Bates retweeted
Meet Zandawala@zandawalaOct 18
The final version of our paper on Drosophila brain endocrine cells is out now in @eLife elifesciences.org/articles/1… Check out the thread from the first author @theresa_mckim here for more details: xitter.cf/theresa_mckim/status/2…

Synaptic connectome of a neurosecretory network in the Drosophila brain

Connectome-level analysis of the Drosophila neuroendocrine system reveals the organizational logic by which the brain integrates sensory information to regulate hormonal signaling.

elifesciences.org
Theresa McKim@theresa_mckimOct 18
🧠🪰 Excited to share our paper in @eLife detailing the synaptic connectome of the neurosecretory network in Drosophila. We mapped the hormone-releasing neurosecretory cells (NSCs) in the fly brain and their connectivity. 🧵 doi.org/10.7554/eLife.102684
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Alexander Bates retweeted
Theresa McKim@theresa_mckimOct 18
🧠🪰 Excited to share our paper in @eLife detailing the synaptic connectome of the neurosecretory network in Drosophila. We mapped the hormone-releasing neurosecretory cells (NSCs) in the fly brain and their connectivity. 🧵 doi.org/10.7554/eLife.102684
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⏳ One month left to enter the RES #InsectWeek Photography Competition! If you've been meaning to sort through your favourite insect photographs, now's the time. We can't wait to see the incredible images you've captured. 📸 Deadline: 31 October insectweek.org/art-and-photo…
Close-up of a pink grasshopper on a green stem promoting the Insect Photography Competition by the Royal Entomological Society. Pink Orthoperan (c) Beverley Brouwer

ALT Close-up of a pink grasshopper on a green stem promoting the Insect Photography Competition by the Royal Entomological Society. Pink Orthoperan (c) Beverley Brouwer

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Alexander Bates retweeted
Akos Nyerges@AkosNyergesSep 19
Proud and excited to share our first preprint 🚀 in which we • create a high-fitness firewalled organism, • that stably colonizes the mouse gut for >100 days, • resists all tested phages in the gut, • and blocks horizontal gene transfer. + Chimera genomes to tailor synthetic
Firewalled synthetic commensal blocks horizontal gene transfer in the gut

ALT Firewalled synthetic commensal blocks horizontal gene transfer in the gut

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Alexander Bates retweeted
FlyWire@FlyWireNewsSep 14
Want to build your own fly simulator on the BANC connectome (the full brain + CNS from a female fly, ~160k neurons)? Here's how. 🧵 TLDR point your agent here: docs.google.com/document/d/1…
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Alexander Bates retweeted
Peter Wang
@BrainsAndTennisSep 14
Replying to @as_bates @nicochristie
thank you! have been a big fan of this field in my sys neuro days, including rachel's work, so wanted to play around :)
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There have been hundreds of scientific findings from the various connectome releases, and from their data while they were in construction, over the last 10 years.
nico
@nicochristieSep 14
What started off as trying to turn the fly gay might have led to the first meaningful scientific finding from the connectome release
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It is very cool that the connectome release has drawn people in @nicochristie @BrainsAndTennis , central complex in particular is a beautiful system and fertile ground for theorising.
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Modelling the whole fly brain from just the connectome and thinking that reveals something about fly behaviour, is a bit like modelling traffic flow out of Google maps and thinking you understand the world economy. Not unrelated, but not that close.
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Alexander Bates retweeted
Cell@CellCellPressSep 4
In the latest issue! The complete gustatory connectome of adult Drosophila reveals how taste guides feeding, foraging, and social behavior dlvr.it/TVKvgd

The complete gustatory connectome of adult Drosophila reveals how taste guides feeding, foraging,...

The complete gustatory system and the full set of feeding motor neurons of adult Drosophila are mapped at synaptic resolution, enabling the identification of taste neuron types and their likely...

cell.com
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Alexander Bates retweeted
FlyWire@FlyWireNewsSep 4
Replying to @GoogleResearch @HHMIJanelia
Congrats on this excellent resource for the connectomics world! For anyone curious, you can explore the MaleCNS data in Codex: codex.flywire.ai/?dataset=mc…
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With a new, amazing and full central nervous system fly connectome in the news today for the male, a reminder that there is also a full female central nervous system available! nature.com/articles/s41586-0…
News from Google
@NewsFromGoogleSep 3
For the first time, scientists have mapped the complete brain and central nervous system of an adult male fruit fly — a key model organism in science. 🪰 Working alongside HHMI Janelia Research Campus and the scientific community, @GoogleResearch scientists and researchers used AI to combine millions of 2D images into 3D neural shapes, reconstructing a record-breaking 166,000+ neurons. This foundational map of the adult male fruit fly brain can help accelerate our understanding of the brain, and is a major milestone in neuroscience.
Vibrant 3D digital reconstruction of a fruit fly brain against a white background, displaying a dense, intricate network of multicolored neural fibers and cell bodies in shades of blue, cyan, orange, and purple.

ALT Vibrant 3D digital reconstruction of a fruit fly brain against a white background, displaying a dense, intricate network of multicolored neural fibers and cell bodies in shades of blue, cyan, orange, and purple.

A complex 3D visualization of a fruit fly brain, featuring a dense, symmetrical network of thousands of tiny, multicolored neurons and fine, interconnected fibers in shades of blue, magenta, orange, and green against a solid white background.

ALT A complex 3D visualization of a fruit fly brain, featuring a dense, symmetrical network of thousands of tiny, multicolored neurons and fine, interconnected fibers in shades of blue, magenta, orange, and green against a solid white background.

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Alexander Bates retweeted
News from Google
@NewsFromGoogleSep 3
For the first time, scientists have mapped the complete brain and central nervous system of an adult male fruit fly — a key model organism in science. 🪰 Working alongside HHMI Janelia Research Campus and the scientific community, @GoogleResearch scientists and researchers used AI to combine millions of 2D images into 3D neural shapes, reconstructing a record-breaking 166,000+ neurons. This foundational map of the adult male fruit fly brain can help accelerate our understanding of the brain, and is a major milestone in neuroscience.
Vibrant 3D digital reconstruction of a fruit fly brain against a white background, displaying a dense, intricate network of multicolored neural fibers and cell bodies in shades of blue, cyan, orange, and purple.

ALT Vibrant 3D digital reconstruction of a fruit fly brain against a white background, displaying a dense, intricate network of multicolored neural fibers and cell bodies in shades of blue, cyan, orange, and purple.

A complex 3D visualization of a fruit fly brain, featuring a dense, symmetrical network of thousands of tiny, multicolored neurons and fine, interconnected fibers in shades of blue, magenta, orange, and green against a solid white background.

ALT A complex 3D visualization of a fruit fly brain, featuring a dense, symmetrical network of thousands of tiny, multicolored neurons and fine, interconnected fibers in shades of blue, magenta, orange, and green against a solid white background.

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Alexander Bates retweeted
Cell@CellCellPressSep 3
New issue is out👉cell.com/cell/current On the cover: the complete connectome of the male adult D. melanogaster central nervous system. The cover depicts a single representative cell from each of the 11,710 neuron types in the dataset, which contains 166,700 neurons in total.
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Alexander Bates retweeted
Bill Katz@wtkatzSep 3
Our male CNS paper is out in Cell.
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Alexander Bates retweeted
HHMI
@hhmi_scienceSep 3
(1/2) When Janelia set out to map every neuron in the fly brain in 2008, many thought it couldn’t be done. Nearly 20 years later, a complete wiring diagram of the 166,000+ neurons of the adult male fruit fly is helping to reveal the brain’s secrets: bit.ly/4zT7jPf.
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Alexander Bates retweeted
HHMI
@hhmi_scienceSep 3
(2/2) Connectome collaborators: @Cambridge_Uni, @ChampalimaudF, @GoogleResearch, MRC Laboratory of Molecular Biology, UK Research and Innovation
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Alexander Bates retweeted
Zhihao Zheng@zhihaozhengAug 7
Happy to share the CA3 dataset is published. First large-scale dense connectomics from hippocampus. First connectomic dataset imaged in @PrincetonNeuro. A harbinger of many larger datasets to come (for both). doi.org/10.1038/s41593-026-0… (1/3)

Hippocampal CA3 connectomics reveals a gradient of mossy fiber inputs and selective feedforward...

Nature Neuroscience - The authors present a dense connectomic reconstruction of a 0.1 mm3 hippocampal CA3 volume and reveal spatial gradients, high convergence and cell-type-selective...

nature.com
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Alexander Bates retweeted
Amy Robinson Sterling
@amyneuronsSep 2
My render on the cover of Nature Neuroscience! And our research inside :) @zhihaozheng ‘s work! Hippocampus data available at pyr.ai Check out more visuals from the brain’s hub of memory and navigation in the thread below!
Nature Neuroscience
@NatureNeuroSep 1
Our September issue is now live! nature.com/neuro/volumes/29/…
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Alexander Bates retweeted
Amy Robinson Sterling
@amyneuronsAug 4
Just a bunch of neurons moving through time
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