Comprehensive review on diagnostic criteria and classification of malignant glandular lesions of the urinary bladder by Dr. Fanni Santa @FV_Santa and her colleagues, published as the featured cover article @Human_Pathology.   This review provides a practical framework for one of the most diagnostically challenging areas in genitourinary pathology, integrating contemporary morphologic, immunohistochemical, and molecular advances into a unified diagnostic approach.   Dr. Fanni Santa and her colleagues address the classification and differential diagnosis of primary bladder adenocarcinoma, urachal adenocarcinoma, Müllerian-derived tumors, and precursor lesions, emphasizing key diagnostic pitfalls in distinguishing these uncommon neoplasms from more common primary bladder tumors and secondary involvement by tumors from other organs. The review also highlights emerging molecular insights, including recurrent genomic alterations with potential therapeutic implications, and discusses evolving concepts surrounding precursor lesions such as villous adenoma, cystitis glandularis with intestinal metaplasia, and adenocarcinoma in situ.   This comprehensive review is an essential resource for pathologists, urologists, oncologists, and trainees, and hope it will contribute to improved diagnostic accuracy, multidisciplinary communication, and optimal patient management for these rare but clinically significant tumors. Read the full article here: sciencedirect.com/science/ar…

Good news to share! Our paper, "Hereditary Renal Cancer Syndromes: Redefining Clinical Management in the Era of Precision Medicine", has been accepted for publication in European Urology (journal impact factor:29)!   It has been a true honor and privilege to work with Dr. Fanni Santa @FV_Santa , an exceptionally talented and dedicated physician-scientist. Fanni completed this work during her observership at @BrownPathology last month - an extraordinary achievement that speaks to her intellectual curiosity, work ethic, and passion for academic medicine.  Fanni is undoubtedly one of the brightest rising stars in genitourinary pathology, and I look forward to many more collaborations and to watching your continued success.