Lorenzo Barchi

Tomorrow @LGaccione2974 from @balurens' lab will explain on our @nanopore day at HHU Düsseldorf, how to turn 9.41 data(!) into a high quality pangenome. If you can't make it read all about it here as well: nature.com/articles/s41467-0…

8/8 And iii) chlorogenic acid metabolism potentially caused by a GDSL-lipase like gene nature.com/articles/s41467-0…

7/8 ii) fusarium wilt resistance with QTL comprising RPP13-like disease resistance genes as well as a AT-hook motif nuclear-localized (AHL) protein

6/8 We also analyzed 218 traits (agronomic, resistance to biotic and abiotic stresses, fruit metabolic composition) scored in 3 field trials, in Spain, Italy and Türkiye among them i) prickliness. where we could pinpoint an interesting LOG translocation.

5/8 The “core” genome of eggplant was found to consist of around 16,300 gene families, (present in all varieties) while around 4,000 gene families were “dispensable” (i.e. they were present in only one or few varieties).

4/8 We then focused on 368 varieties, representative of the worldwide phenotypic and genetic diversity of eggplant and comprising its wild progenitors, Solanum incanum and Solanum insanum. We constructed a graphical pangenome…

2/8 We had started from a large worldwide collection of 3,400 eggplant varieties and wild progenitors and used it to reconstruct its domestication history in India and South-East Asia, and its later expansion nature.com/articles/s41467-0… doi.org/10.1111/tpj.16455.

3/8 This led to the observation that for instance, the varieties coming from India and South-East Asia have retained the non-purple skin colour and the spiny leaves characteristic of their wild ancestors, while these traits were progressively lost in the other geographical areas.

1/8 How do graph pangenomes and panphenomes help breeding eggplant? doi.org/10.1038/s41467-025-6…. This feat would not have been possible without a large team of 24 researchers from 7 countries including @ProhensJaime @giulianolab1 @solgenetics and BarchiLab