carolinebsirini, MD (@cbsirini) header
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Cytopathology fellow @Emorypathology/ former GI path fellow and resident at @pathology_URMC

Joined November 2017
Photo by carolinebsirini, MD (@cbsirini)Photo by carolinebsirini, MD (@cbsirini)Photo by carolinebsirini, MD (@cbsirini)Photo by carolinebsirini, MD (@cbsirini)Photo by carolinebsirini, MD (@cbsirini)Photo by carolinebsirini, MD (@cbsirini)Photo by carolinebsirini, MD (@cbsirini)Photo by carolinebsirini, MD (@cbsirini)Photo by carolinebsirini, MD (@cbsirini)Photo by carolinebsirini, MD (@cbsirini)
My beautiful CNSET case!
15 yo f presented to ED w/acute onset of RLQ abd pain. CT scan revealed an incidental 14 cm heterogenous mass in the right lobe of the liver. Case by Caroline Bsirini MD, Karen Vanderbilt BS, Lee Ann Hellman PA (ASCP), Michael G. Drage MD, PhD, #Liverpath buff.ly/2Asns4U
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carolinebsirini, MD retweeted
Basic medical liver pathology! wanna explore the histological features of chronic cholestasis? Look no further - 3 minutes and 30 seconds. #GIpath
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PPI-induced clear cell change in gastric parietal cells. Note sparing of the foveolar epithelium. Previously described in detail by @RunjanChetty and colleagues. Don’t mistake for signet ring cells!#GIpath @DraEosina @ariella8 @kriyer68 @SingJamieD @Pathmath1 @jansen_marnix
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carolinebsirini, MD retweeted
Inflammatory rhabdomyoblastic tumor, initially thought to be a smooth muscle neoplasm in part because myogenin expression is limited - PAX7 is typically diffuse #BSTPath
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carolinebsirini, MD retweeted
Liver lesion. Adult. Diagnosis anyone? #GIpath @MGHPathology
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carolinebsirini, MD retweeted
A stomach resection.. what do you think? 😃 #PathTwitter
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carolinebsirini, MD retweeted
An interesting #ENTpath #oralpath case. a 1 cm lesion at the Stensens duct.
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🔬EMORY CASE OF THE WEEK #53: 23F w/ no significant medical history with 12 cm mass in left lobe of liver. Answer the question below! Contributor: Zaid Mahdi, MD (@zaid_mahdi) & Melanie Bourgeau, MD (@MELanocyteMD) #gipath #liverpath #pathresidents #Emorypathres #EmoryCoTW
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carolinebsirini, MD retweeted
Side by side comparison of what I would consider "typical parakeratosis" versus "atypical parakeratosis" 🔅In typical, you have nice small bland pyknotic nuclei 🔅In atypical, the nuclei are relatively enlarged with irregular contours #CytoPath #PathTwitter
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carolinebsirini, MD retweeted
A tutorial on eosinophils and a tutorial on adenosarcoma. Both excellent but which one did you learn more from? Please vote. 👇🏾🙏🏾
Seed 3
38%@MELanocyteMD
62%@AMubeen_Path
435 votes • Final results
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carolinebsirini, MD retweeted
#Pathologists ♥️ eosinophils. We love scanning for them in a skin rash, admiring them when they infiltrate a tumor, & even counting them in esophageal biopsy. 🔬 But what do you know about eosinophils in the blood? 🤔 1/ #pathbracket #hemepath #pathtweetorial @EmoryPathology
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carolinebsirini, MD retweeted
"Standing Tall" - The aggressive Tall Cell Variant (TCV) of Papillary Thyroid CA. I don't routinely give "variant dx" in my practice. However, in cases, I may put a note "Focal features suggest a TCV", which maybe helpful to the surgeon to decide on the extent of nodal resection.
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carolinebsirini, MD retweeted
Look who’s visiting this appendix! Enterobius Vermicularis (pinworms), they belong to nematodes. Note the eggs, lateral ala and intestine! Diagnosis by identifying the eggs using cellulose tape slide test, morning collection is better @cbsirini @GIPathologyURMC #GIpath
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carolinebsirini, MD retweeted
Challenging on frozen section, but still one of my favorites. 54 yo F with postmenopausal bleeding and ovarian mass. 1) Diagnosis? 2) Mutation? 3) What are the vacuoles?
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carolinebsirini, MD retweeted
Pleural fluid specimen from a patient with catamenial pneumothorax. #cytology #cytopath
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carolinebsirini, MD retweeted
I call this a “Slam Dunk Melanoma”, no IHCs needed. Pigment and macronucleoli are there but I consider the cytoplasmic tails (arrow) as one of the most characteristic feature on Cyto.
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carolinebsirini, MD retweeted
Medicine has limitations We don’t have all the answers Just because we cannot see or diagnose one’s health concern, this does NOT mean that they are not suffering Lets not dismiss a human being’s concerns This only amplifies their suffering #mondaythoughts #MedTwitter
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carolinebsirini, MD retweeted
Voided urine specimen. High grade urothelial carcinoma cell with an interesting morphology. #cytology #cytopath #WALLE
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carolinebsirini, MD retweeted
A bit degenerated, but nice case of HGUC with 'umbrella cell-like' morphology. Tumor cells have more abundant cytoplasm, but nuclei are obviously malignant with enlargement (over 10x the size of a RBC), hyperchromasia, and extremely irregular contours. #cytology #cytopath
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carolinebsirini, MD retweeted
Pancreatic Cytopathology and Nature. Another gorgeous “SPN”.
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