@clarnedo

Computational biologist | Postdoc @aitken_lab @MRC_TU working in genomics & pathomics in cancer and human disease

 Cambridge, UK
Joined December 2017
  • Tweets301
  • Following635
  • Followers444
17Media
We’re very happy to see this finally out! “Hotspot propensity across mutational processes” with @fmuinos @abel_gonzalezp @nlbigas @bbglab @IRBBarcelona Can mutational hotspots help to study the mutation rate variability at single-nucleotide resolution? --> doi.org/10.1038/s44320-023-0…
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The genomic landscape of 2,023 colorectal cancers is out! I’m very grateful to have collaborated with such a great team on this massive project! Check all the findings here --> nature.com/articles/s41586-0…

The genomic landscape of 2,023 colorectal cancers

Nature - Whole-genome sequencing of more than 2,000 colorectal carcinoma samples provides a highly detailed view of the genomic landscape of this cancer and identifies new driver mutations.

nature.com
Houlston Lab, ICR@HoulstonLab_ICR7 Aug 2024
Another day, another publication 😎 We are extremely pleased to share our analysis of #colorectal #cancer whole #genomes in @GenomicsEngland now published in @Nature nature.com/articles/s41586-0…

The genomic landscape of 2,023 colorectal cancers

Nature - Whole-genome sequencing of more than 2,000 colorectal carcinoma samples provides a highly detailed view of the genomic landscape of this cancer and identifies new driver mutations.

nature.com
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Just on time for #DNADay let me introduce you to Pol the polymerase. Pol was happily replicating a strand of DNA when something unexpected happened... 1/6
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This comic is the result of a wonderful collaboration with science illustrator @ClaudiaFlandoli and @S_J_Aitken @aitken_lab @sophtalkssci at @MRC_TU @Cambridge_Uni I’m super happy and thankful to have worked on this! 5/6
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Hope you enjoy this as much as we did and stay tuned for new versions of the comic in more languages! 🌍6/6
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Claudia Arnedo Pac retweeted
Anthony Mathelier@AMathelier19 Jan 2024
Looking for a postdoc in my group @NCMMnews @NordicEMBL @UniOslo_MED @unioslo_mn @unioslo_bioinfo to enhance computational resources for regulatory genomics (JASPAR & UniBind) with deep learning. Project in collaboration with @anshulkundaje & @WyWyWa jobbnorge.no/en/available-jo…
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Claudia Arnedo Pac retweeted
IRB Barcelona
@IRBBarcelona10 Jan 2024
🧬Hotspot propensity across mutational processes. 📰@MolSystBiol-@EMBOPress ✍️@clarnedo @fmuinos @abel_gonzalezp @nlbigas (@bbglab). ➡️bit.ly/3SdCVeL 📌doi.org/10.1038/s44320-023-0… #IRBScience
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Claudia Arnedo Pac retweeted
bbglab@bbglab22 Dec 2023
Can mutational hotspots help to study the mutation rate variability at single-nucleotide resolution? Follow Claudia's thread on her lalest paper to know more. Congrats @clarnedo , @fmuinos , @abel_gonzalezp and @nlbigas for the great work.
Claudia Arnedo Pac@clarnedo22 Dec 2023
We’re very happy to see this finally out! “Hotspot propensity across mutational processes” with @fmuinos @abel_gonzalezp @nlbigas @bbglab @IRBBarcelona Can mutational hotspots help to study the mutation rate variability at single-nucleotide resolution? --> doi.org/10.1038/s44320-023-0…
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Claudia Arnedo Pac retweeted
Mol Syst Biol@MolSystBiol20 Dec 2023
The propensity of #mutationalsignatures to leave mutational hotspots serves as an estimate of the variability in their mutational probability at single-nucleotide resolution ➡️ embopress.org/doi/full/10.10… @nlbigas @IRBBarcelona #cancergenomics
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Thanks to everyone who supported our work, specially patients, families and researchers who shared and made available all the data used in our study #PCAWG @HartwigMedical @cbioportal @StJude #TARGET and others
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As well as funders including @ERC_Research @CienciaGob @FundlaCaixa @BecariosFLC @ContraCancerEs @IRBBarcelona @iCERCA
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And thank you all for reading!
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