In vivo CRISPR-Cas optimizations and applications to understand early development and human diseases at UPO-CABD, Seville. Tweets from M.A. Moreno-Mateos

Sevilla, España
Joined September 2015
Congratulations to the new PhD @CABD_UPO_CSIC: Carlos Sánchez Bolaños ! Dr. Sánchez presented and discussed his PhD work marvellously! Carlos's thesis was done with the PhD program of @pablodeolavide supervised by Miguel A. Moreno Mateos!
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Moreno-Mateos Lab retweeted
6/6 🐑 En el nuevo episodio de Memorias de Dolly conocemos estas investigaciones de la mano de los doctores Manuel Sánchez Martín (@usal) y @crisprscan (@CABD_UPO_CSIC; @CSIC). También explicamos cómo funciona CRISPR, sus limitaciones y los dilemas éticos que plantea.
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¡Un vídeo a no perder sobre #CRISPR que cuenta con la participación de Miguel Ángel Moreno Mateos del #CABD! @CSICdivulga @CSIC
1/6 🧬✂️ ¿Y si modificamos nuestro ADN para corregir las mutaciones que provocan enfermedades? Vamos con CRISPR-Cas, una tecnología que ha cambiado por completo la forma en la que los científicos pueden modificar los genes de los seres vivos. Os contamos cómo funciona. 🧵👇
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Moreno-Mateos Lab retweeted
🧬🌊 New preprint from our lab: DO1 Cas9, the first Cas9 nuclease characterised from the deep ocean — recovered from a metagenome at 1,500 m in the Atlantic. ❄️Cold-adapted: it cuts DNA efficiently at low temperature, where mesophilic SpCas9 retains only residual activity. 🧵1/4
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This Monday, Miguel Ángel Moreno Mateos from #CABD presented the work ¨CRISPR-Cas RNA-targeting optimizations and screenings in vivo¨ as an invited speaker during the plenary session in ‘Regeneration and Stem Cell Biology’ at the #ZDMS19 in Oxford, UK!
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Happy that @Luisherhuertas thesis has been awarded as the best in Spain (year 2025) by the Spanish Society of Developmental Biology. Congratulations Luis! More than deserved!
I can not be prouder of Luis. He has been absolutely essential for our science and has been a fantastic researcher, wonderful colleague and definitely a role model in the lab. Thanks Luis for sharing these years with us!
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Amazing talk last Friday at #CABDseminars by Raúl Pérez-Jiménez from @CICbioGUNE! Raul was hosted by @crisprscan Thanks for coming Raúl!
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#CABDseminars "RNA-guided nucleases: Understanding their origins and applications" by Raúl Pérez-Jiménez , @CICbioGUNE 🗓️ July 3rd ⏰12 pm 📍Rosalind Franklin Auditorium, CABD Hosted by @crisprscan
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Moreno-Mateos Lab retweeted
In January, I reviewed a Review for a crappy MDPI journal. It was 100% AI, missing citations, etc. I sent a massive report, and the authors withdrew it. Today, I see it published without a single change in another even crappier MDPI journal.
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#SEBD2026 is now ON!!! Check the website, speakers, program & important deadlines! 🔗 sebd2026.com/ 📅 28th-30th October, 2026 📍El Rompido ‼️Early registration: June 20th Great scientific gathering coming up! (1/2)
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Super happy that @Luisherhuertas work recently published in the EMBO Journal was awarded as best paper of the year in the @CABD_UPO_CSIC! A great way to end the year!
🏆 Telonero Award- best paper organized by Marta Artal with Carlos Santos, Inés Canosa, Juan R. Martínez Morales and Gretel Nusspaumer 🥇Luis Hernández Huertas 🥈Irene Molina 🥉Daniel Barcenilla
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¡Enhorabuena al equipo responsable por el trabajo publicado en @embojournal que ha sido co-liderado por @BazziniLab de @ScienceStowers & @crisprscan del #CABD!!!
🧬 Revelan por primera vez un mecanismo esencial para el inicio de la vida en los vertebrados 🔬 Gracias a una herramienta #CRISPR que elimina el ARN investigadores del @CABD_UPO_CSIC han descubierto un nuevo factor crucial en la #fertilidad 👉 f.mtr.cool/huiohedxfj
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Fenomenal nota de prensa de nuestra última contribución para entender un poco mejor los primeros eventos durante la embriogenesis. @Luisherhuertas @CABD_UPO_CSIC @bazzi embopress.org/doi/full/10.10…
🧬 Revelan por primera vez un mecanismo esencial para el inicio de la vida en los vertebrados 🔬 Gracias a una herramienta #CRISPR que elimina el ARN investigadores del @CABD_UPO_CSIC han descubierto un nuevo factor crucial en la #fertilidad 👉 f.mtr.cool/huiohedxfj
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Happy to see this finally out! We have coordinated a network where many labs from different institutes in South Spain have participated. Our aim is to join efforts to support the use and develop of genome and RNA editing tools and research models in biomedicine (1/2)
📢 El @CABD_UPO_CSIC en #Sevilla lanza un nuevo catálogo que recoge biomodelos y herramientas en edición genómica disponibles para su uso en investigación bajo la subvención de Andalucía Biotec Salud. 👀 ¡Lee la noticia en nuestro blog! planescomplementariossalud.e…
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We have generated a catalog where many resources are shared to ultimately establish collaborations within the region but also national and internationally. If you feel that you can also support the network contact and join us! Take a look to the website: biogenec.andaluciabiotec.csi…
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Please take a look to this fantastic thread of @Luisherhuertas leading this work from our lab that pioneers the use of CRISPR-RfxCas13d screenings to uncover new maternal regulators of early development in fish. More exciting screenings are coming with new factors, stay tuned! :)
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It has been great to spend a few days in such a beautiful venue with fantastic science and fun! So happy to see that this workshop grows nicely. Looking forward to 2027 edition!
Our colleague, collaborator and friend @crisprscan have showed with his genuine enthusiasm their advances on RNA Cas13 nucleases and other Cas nucleases for DNA. #EMBOCRISPRcas #CRISPR
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Still open to get applications for this postdoctoral position. Please send me the required information. Also, I will be in two weeks in Sorrento for the CRISPR-Cas workshop, so if you are around and would like to work in our lab, this would be a great opportunity to meet :)
Hi there! We are lookig for a highly motivated and talented postdoctoral researcher to join our dynamic team starting in 2026. Please see the call for more details! Come on join us! It will be fun! :)
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