👨🏽💻 founder x3 👧🏼 father and ⛰️ mountains lover
Paris, France
Joined August 2010
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david GAUTIER 🕴🏽 retweeted
Surprise 1: Anthropic acquired a one-person biotech
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Surprise 2: that person is me
Surprise 3: I’m here to tell you all about it
Yes, this is what you think it is; after 6 yrs of increasingly loose anonymity: the Professor Oak reveal post
…and yes, it has gotten so boring around here that I’m literally doxxing myself to spice up the timeline
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Ok, allow me to introduce myself. My name is Cody Tranbarger. I mostly tweet, but occasionally find time to dabble in drug dev & starting/building biotechs. My past lives span the VC, crossover, startup continuum; Prof Oak has been my way of keeping a digital foot in those worlds, despite having my physical feet planted elsewhere.
The past 18 mo, ‘elsewhere’ was Mithril Medicine, a co. I founded to develop bsAbs for LAMA2-CMD & other ECM-related genetic diseases.
Mithril was born out of hands-on building with @MikeNGladstone, @JasonPaulRhodes, @LifeSciVC, & team @atlasventure. Somehow, I made enough half-decent calls along the way (even a broken clock is right twice a day, eh?) to convince them Mithril/I warranted a small seed. While I can hardly rationalize such an outrageously cavalier bet, I’m grateful for it, & I'd partner with Atlas again in a heartbeat.
In typical AV fashion, Mithril’s primordial form was virtual, decentralized, & ultra-lean. This stage tends to be short-lived, but for Mithril, it worked surprisingly well, for surprisingly long, thanks in part to the rapid maturation of the AI tools I used liberally.
Eventually, Mithril became a bit of an experiment itself - to find the upper bound of how far it could scale as a single operator + a bunch of Claude (+ a stellar bench of part-time consultants).
In parallel, I started spending time with @nc_frey, @an1lam, & @CoefficientBio team; and promptly experienced, for the 1st time, AI at the frontier. Soon thereafter, Mithril stopped looking like an experiment, & started looking like a preview of an entirely new operating model.
From that spark came “Pipeline-in-a-Person.” The idea immediately resonated when we shared it here back in April; and it was central to the shared vision that led to Anthropic’s acquisition of Mithril, & my joining the team.
Why join Anthropic? Three reasons.
(1) For Mithril, the programs continue, with more resources & infrastructure behind them, and as much Claude as I can put to work.
(2) For me, the chance to start several more programs, & find out how many one person can actually run in parallel - an almost unprecedented luxury for a curious drug hunter.
(3) For our mission, a path to institutionalize & scale this new way of working, then put it in the hands of all of biopharma, all over the world - which, candidly, I find the most energizing.
Will AI x Bio cure diseases? Unequivocally yes, imo… but not by the route that gets the most airtime. Rather than timeline acceleration & compression, I see orchestration & parallelization as today's low-hanging fruit.
Most drug hunters see a handful of go/no-go calls in a career, & spend entirely too much of the rest trading emails (my inbox can attest).
Give them the bandwidth to run several programs at once, and the time to focus on scientific judgment, and I’m willing to bet they’ll make better calls. And at scale, better calls translate to more drugs, higher hit rates, broader patient impact, & likely, a disease or 10 or 100 cured. I couldn't be more excited to build toward that future @AnthropicAI.
Finally, a heartfelt thank you to BioTwitter/X. The end of anonymity is bittersweet, but if anyone’s earned a proper introduction, you all have.
It’s difficult to overstate how much this app has done for me: a decade of education, plenty of friends, many job opportunities, several mentors, a few investors, even a co-founder (fmr). It was the generosity of this community that inspired me to start posting 6 years ago, after just as many years lurking. I hope I’ve been able to pay it forward, in my own small way.
But, to be clear, Prof Oak isn’t going anywhere. Same beat, same themes, and now, a front-row seat to drug development at the frontier. Stay tuned for dispatches from the trenches; and remember...
Gotta Cure 'Em All
david GAUTIER 🕴🏽 retweeted
🏆 Félicitations à Christophe Botella, lauréat du Prix du Collège de France (@cdf1530) pour les jeunes chercheuses et les jeunes chercheurs 2026, consacré cette année aux "Sciences #mathématiques pour la planète".
➕ En savoir plus : college-de-france.fr/fr/actu…
david GAUTIER 🕴🏽 retweeted
Ten years ago today, Zipline made the world’s first lifesaving drone delivery in Rwanda.
Three million deliveries later, more than 60,000 lives have been saved. Meet the people on the other end of these deliveries in our new video series, Stories from the Sky.
david GAUTIER 🕴🏽 retweeted
This is the way ❤️
Jensen reveals he first met the Founder of TSMC by cold calling their number off Yellow Pages
"I heard about this company in Taiwan, TSMC and UMC at the time. They were of course quite poor companies themselves, and they were barely making it."
"TSMC was probably about $300 million, something like that. It's a tiny little company. I heard about Morris Chang. And so I tried to call their US office."
"Back in the old days there were yellow pages. I looked it up, TSMC. There's a number there. I called their number and it's a recording. I left my name and my number and said a few things about NVIDIA: we're a new startup company building computer graphics chips. I called several times. Nobody called me back."
"And so I finally wrote a letter to Morris Chang. Didn't hear anything for a long time, and then one day it was 6 o'clock or something, this person called and said 'this is Morris Chang from TSMC.'"
"And meanwhile, everybody outside my office was playing video games and they're all laughing and screaming. 'Hey shut up! It's Morris!' I was so happy that the founder would actually call us back, because hey, maybe we won't have to die."
"And so we talked and he invited me to Taiwan. I came back to Taiwan, and that was the start of everything. Not just that partnership, but just the whole industry."
david GAUTIER 🕴🏽 retweeted
Watch Dragon and Crew-12 return to Earth teapawt.net/i/broadcasts/1DGLdZyZZ…
david GAUTIER 🕴🏽 retweeted
j’apprécie Arthur nous avons eu l’occasion d’échanger à plusieurs reprises en privé et je souhaite sincèrement le meilleur à mistral pour l’avenir, par contre y’a 3 points essentiels que je tiens à exposer sur les déclarations de Juan qui ne fait au fond que reprendre ce que je répète ici publiquement depuis des années donc rien de nouveau sous le soleil pour ceux qui me suivent depuis des années
déjà pour rappel l'affaire Cédric o et son investissement dans Mistral (dont je parle ici depuis un long moment) est l'incarnation absolue d'un capitalisme de connivence où la capture de rente étatique supplante la création de valeur technologique pure
j’en ai déjà parlé également mais pour info cela avait d'ailleurs provoqué de lourdes tensions internes entre certaines grandes figures d'Ulm et cédric (des histoires d'appareil qui ne me regardent pas mais qui illustrent parfaitement comment la haute administration instrumentalise l'excellence académique pour légitimer une captation d'actifs sous couvert de souveraineté)
deuxième point qui concernele forcing de Macron (déjà évoqué ici à plusieurs reprises) auprès des pdg du cac 40 pour imposer la signature de contrats mistral et qui en réalité fabrique une illusion de traction et fausse totalement la découverte naturelle du produit par le marché
en tordant le bras des grands groupes pour gonfler une vitrine nationale l'état crée un mirage de product market fit sauf qu'une vitrine bâtie sous pression politique ne tient que tant que la main du pouvoir reste posée dessus et malheureusement la la gravité économique mondiale finit toujours par rattraper les arrangements de couloir et le jour où la pression du prince s'atténue la réalité de la compétition brute reprend ses droits
troisième point que j’ai TRÈS LARGEMENT couvert au point d’être devenu l’ennemi public numéro 1 de tous les enfants de bourgeois d’HEC et autres scammeurs de la frentech mais qui dépasse largement le cas mistral reste que la FrenchTech ets un écosystème verrouillée par un entre soi consanguin de fils à papa où des VCs (d’HEC également et qui n’ont jamais rien construit de leur vie) sont pétrifiés par l'aversion au risque et pratiquent un mimétisme social aveugle au lieu de chercher des anomalies de marché et de l'asymétrie radicale
ces investisseurs frileux avec un balais dans le cul préfèrent financer des miroirs sociologiques pour minimiser leur risque réputationnel individuel et malheureusement ce système de caste financé par l'argent public et protégé par l'appareil d'état produit des colosses aux pieds d'argile incapables d'affronter la sélection naturelle de l'innovation mondiale sans un protectorat politique permanent
en d’autre termes ces VCs obsédés par la minimisation du risque investissent uniquement chez des profils qui leur leur ressemblent et ce biais mimétique supprime toute possibilité de vraie disruption en finançant la conformité sociale plutôt que le talent brut et la prise de risque asymétrique
in fine cette noblesse d'état déguisée en écosystème tech est la raison exacte pour laquelle la france fabrique des vitrines politiques sous perfusion au lieu de bâtir des monopoles technologiques mondiaux capables de survivre à la brutalité du réel
cette consanguinité financière et sociale est incapable de produire de l'anti fragilité (cc à mon ami @nntaleb) et condamne l'écosystème à produire des illusions subventionnées plutôt que des géants technologiques souverains
This quoted post is unavailable.
david GAUTIER 🕴🏽 retweeted
A vomir
Je ne veux plus jamais entendre « il est Français comme vouzémoi » même pour les sportifs de talent.
MBappé, Teddy Riner, etc peuvent faire carrière et jouer sous nos couleurs, ils défendront toujours avant tout leurs congénères contre les Français de souche.
Readers added context they thought people might want to know
Riner est né à Pointe-à-Pitre, en Guadeloupe française depuis 1635, département depuis 1946.
Mbappé est né à Paris. Français de naissance.
fr.wikipedia.org/wiki/Teddy_Rin…
teddyriner.com/l-athlete/
la1ere.franceinfo.fr/il-y-a-80-ans-…
fr.wikipedia.org/wiki/Kylian_Mb…
david GAUTIER 🕴🏽 retweeted
OMG. I guess we have our answer from OpenAI
“we stole it fair and square”
Not one goddamn mention in the tweet of the human mathematicans they were in communication with, and whom they may well have ripped off.
[Read cims.nyu.edu/~tristanb/state… for what OpenAI did not admit in the tweet.]
Absolutely disgusting.
We’re sharing a solution to the Navier-Stokes Millennium Prize Problem, one of the deepest problems at the frontier of mathematics.
The proof was produced by a group of agents, using an OpenAI next-generation model significantly more capable than GPT-6 Astra.
The problem concerns whether the description of smooth three-dimensional fluid motion modeled by the Navier-Stokes equations can break down. It has remained unresolved for roughly 90 years.
david GAUTIER 🕴🏽 retweeted
The Guardian parle de Nantes.
Conclusion de l'article (traduit en français) : "C’est un projet ambitieux : créatif, non conventionnel et résolument tourné vers l’avenir. Je suis certaine que Jules Verne aurait approuvé." Joanne O’Connor
theguardian.com/travel/2026/…
💪🏽🤓👏🏽
Super happy to share our intention to join forces with NVIDIA in a $12,930,300,000 acquisition 💛💚
10 years after starting Hugging Face, open-source AI is at an inflection point. Thanks to the community, we’ve shown that it can be a complement, and even an alternative, to closed-source APIs. But for it to happen at larger scale, it needs more compute, more support, more collaboration and more visibility. That’s why we went to talk to Jensen, who offered to do exactly that with us.
In addition to doubling down on NVIDIA’s massive contributions to open-source AI (I called them the “King of American open-source AI” earlier this year), they’ve committed to strongly supporting Hugging Face and our mission while keeping the platform open, independent and compute agnostic. The founders and the team are all staying to keep pushing this mission forward.
Together, we think we can make open source the default way to build AI, with the goal of empowering 100 million AI builders to own their intelligence rather than rent it.
Excited about the next 10 years! 🤗🤗🤗
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True
Hugging Face racheté par Nvidia : 12,9 Md$.
Trois fondateurs français: Clément Delangue (CEO), Julien Chaumond (CTO), Thomas Wolf (CSO).
Société créée en janvier 2016 à New York, structurée aux US dès le départ, déménagée là-bas en 2017 pour lever.
La French Tech va revendiquer la sortie. Le cap table est américain depuis dix ans.
Créée le 2 janvier 2016 à New York, initialement basée à Brooklyn. Pas en France. L'entreprise déménage aux États-Unis en 2017 pour lever des fonds. Le plus gros bureau est aujourd'hui à Paris, mais la société est une Inc. américaine depuis le début.
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Pendant ce temps en Europe …
Comment vont les tests au 1/6eme pour évaluer la faisabilité des boosters réutilisables @esa ?
MISSION SUCCESS | ZhuQue-3 Y2 Reusable Launch Vehicle Achieved Full Success in Orbital Insertion and First-Stage Recovery
On August 19, 2026, at 07:35 (UTC+8), the ZhuQue-3 (ZQ-3) Y2 reusable launch vehicle lifted off from the Dongfeng Commercial Space Innovation Pilot Zone. Approximately 137 seconds after lift-off, the first and second stages separated. The second stage continued its flight and successfully delivered the Honghu 03 satellite, independently developed by Hongqing Technology, into its designated orbit. At approximately 07:41, the first stage performed a successful soft touchdown at the LandSpace Landing Site#1 in Minqin County, Gansu Province, following the planned trajectory — marking the full success of the flight test mission.
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david GAUTIER 🕴🏽 retweeted
Yesterday, I was so impressed by Ben Cooper’s photograph capturing the different stages of the solar eclipse in a single image that I immediately started adding the same idea to my eclipse project.
Now it’s tested and ready. You can choose any point on Earth and any solar eclipse from the past 4,000 years or the next 1,000 and see how the Sun moved across the sky during the eclipse.
eclipses.bogachev.fr/?sky=bi…
david GAUTIER 🕴🏽 retweeted
Predicting cyclones accurately can help save lives - and every hour of lead time counts.
Published in @Nature, our AI model WeatherNext achieves state-of-the-art accuracy in forecasting a storm’s track and intensity, giving us a critical extra 24 hours to prepare on average. 🧵
