E. Dalles Keyes (@dalles_keyes) header
E. Dalles Keyes (@dalles_keyes) profile picture

E. Dalles Keyes

@dalles_keyes

Postdoctoral Researcher @UofUpharmacy | Chemistry PhD @UUtah @UtahChemistry | Peptide synthesis and modification 🧪 | Tweets are my own.

 University of Utah
Joined June 2021
  • Tweets36
  • Following180
  • Followers61
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Photo by E. Dalles Keyes (@dalles_keyes)Photo by E. Dalles Keyes (@dalles_keyes)Photo by E. Dalles Keyes (@dalles_keyes)
the Stevens rearrangement remains useful for the synthesis of polycyclic natural products, check out the review @MylesLovasz, @ValitonChelsea, and Zach Schwartz wrote in SYNTHESIS @thiemechemistry: thieme-connect.com/products/… @UtahChemistry @UUtah
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Chemistry News (@ChemistryNews) profile picture
Chemistry News
@ChemistryNews29 Apr 2023
Just Published: Chemoselective, Oxidation-Induced Macrocyclization of Tyrosine-Containing Peptides dx.doi.org/10.1021/jacs.3c00…

Chemoselective, Oxidation-Induced Macrocyclization of Tyrosine-Containing Peptides

Abstract. Inspired by nature’s wide range of oxidation-induced modifications to install cross-links and cycles at tyrosine (Tyr) and other phenol-containin

pubs.acs.org
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Top Science (@isciverse) profile picture
Top Science
@isciverse30 Apr 2023
Chemoselective, Oxidation-Induced Macrocyclization of Tyrosine-Containing Peptides @J_A_C_S @isciverse #Chemistry #ChemTwitter #chemed #scicomm #news #Technology #Tech #NewsBreak #Trending #research #science #AcademicTwitter pubs.acs.org/doi/10.1021/jac…
Image from Top Science (@isciverse)
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please check out the natural product-inspired peptide macrocyclization method we developed, these reactions are fast and simple to perform @UtahChemistry @UUtah @J_A_C_S pubs.acs.org/doi/full/10.102…

Chemoselective, Oxidation-Induced Macrocyclization of Tyrosine-Containing Peptides

Abstract. Inspired by nature’s wide range of oxidation-induced modifications to install cross-links and cycles at tyrosine (Tyr) and other phenol-containin

pubs.acs.org
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congratulations to the team: @dalles_keyes, @MCMChem, @maxjaustin, @brightonalvey, @HaqueLotfa, @AndrieaMerie, Tristin E. Rose, Prof. Bethany Buck-Koehntop, and @MailJyotim
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109.3 Then a preprint @ChemRxiv from Roberts and co-workers @agr_chemistry from the University of Utah on a new oxidative macrocyclization reaction of tyrosine containing peptides doi.org/10.26434/chemrxiv-20…
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The Roberts laboratory is excited to share a @ChemRxiv preprint of our tyrosine-selective peptide cyclization method, with @dalles_keyes @MCMChem @maxjaustin @brightonalvey @HaqueLotfa @AndrieaMerie & Prof. Buck-Koehntop. @UtahChemistry @UUtah chemrxiv.org/engage/chemrxiv…
Image from a. g. roberts chemistry (@agr_chemistry)
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Super excited to finally be able to share a preprint of this work from the @agr_chemistry lab. Good times developing this methodology! Check it out on @ChemRxiv. "Chemoselective, oxidation-induced macrocyclization of tyrosine-containing peptides" doi.org/10.26434/chemrxiv-20…
Image from E. Dalles Keyes (@dalles_keyes)
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congratulations to Dr. Lori D. Digal for an excellent dissertation defense today! 'Synthetic strategies in chemical protein synthesis for peptide ligation and lasso peptides and their isomers' @UtahChemistry @UUtah
Image from a. g. roberts chemistry (@agr_chemistry)
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When you are ready to switch fields for your Postdoc
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“When the world is in trouble, chemistry comes to the rescue.” Love this!
The Nobel Prize (@NobelPrize) profile pictureThe Nobel Prize
@NobelPrize5 Oct 2022
"It was always my hope that, as a scientist, I could make some contributions that would benefit human health." Listen to our conversation with 2022 chemistry laureate @CarolynBertozzi, where she shares why she wanted to become a scientist and the importance of chemistry:

Telephone interview: Carolyn Bertozzi

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E. Dalles Keyes retweeted
The Nobel Prize (@NobelPrize) profile picture
The Nobel Prize
@NobelPrize5 Oct 2022
"It was always my hope that, as a scientist, I could make some contributions that would benefit human health." Listen to our conversation with 2022 chemistry laureate @CarolynBertozzi, where she shares why she wanted to become a scientist and the importance of chemistry:

Telephone interview: Carolyn Bertozzi

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The Nobel Prize (@NobelPrize) profile picture
The Nobel Prize
@NobelPrize5 Oct 2022
BREAKING NEWS: The Royal Swedish Academy of Sciences has decided to award the 2022 #NobelPrize in Chemistry to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless “for the development of click chemistry and bioorthogonal chemistry.”
Image from The Nobel Prize (@NobelPrize)
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Denis Wirtz (@deniswirtz) profile picture
Denis Wirtz@deniswirtz18 Sep 2022
Replying to @McLellan_Lab
Maybe journals should pay reviewers?
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congratulations to Dr. @dalles_keyes for an excellent dissertation defense today! 'Strategies for the selective modification of tyrosine and tyrosine-containing peptides' @UtahChemistry @UUtah
Image from a. g. roberts chemistry (@agr_chemistry)
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congratulations to Dr. @_EmilyKirkeby_ for an excellent dissertation defense! 'Progress toward organocatalyzed native chemical ligation (NCL) & Deaminative ring contraction methods for natural product synthesis' @UtahChemistry @UUtah
Image from a. g. roberts chemistry (@agr_chemistry)
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Congratulations to undergraduate researchers, Mina Done (Burrows group) and Maxwell Austin (Roberts group @agr_chemistry) @UtahChemistry!! They were selected to be the next @UUtah @uofu_science Beckman Scholars @BeckmanFnd @UofUNews
Image from a. g. roberts chemistry (@agr_chemistry)
Image from a. g. roberts chemistry (@agr_chemistry)
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Validation by NMR is great, but getting a crystal structure is just 🔥🔥
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Me when my students ask how much sodium sulfate they should add to their organic extracts
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Toward elucidating the human gut microbiota-brain axis: molecules, biochemistry, and implications for health and diseases. - Lai Y et al. - dx.doi.org/10.1021/acs.bioch… #microbiome
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