Macau-born scientist & educator 🌏 | PhD in Physiology 🧬 | Asst. Dean @ MUST Faculty of Medicine | Training future doctors and advancing cancer research
Macau
Joined February 2009
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Our recent review on #LongCovid suggests decreasing severity and incidence, and changing symptomatology, but could be due to vaccinations.
#FutMed Review
Long COVID across SARS-CoV-2 variants: Clinical features, pathogenesis, and future directions
#SARSCoV2 #OpenAccess @oliviamonteiro @dbaptista
Read now ➡️ doi.org/10.1002/mef2.70004
Learn more➡️ eurekalert.org/news-releases…
ALT Long coronavirus disease (COVID) affects various body systems resulting in heterogeneous symptomatology, which could be due to increased immunity through vaccination or multiple exposures to the virus. Current data indicate that the incidence of long COVID from the severe acute respiratory syndrome coronavirus 2 wild-type variant to Omicron may be decreasing.
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Highlight for Widjaja AA, et al. Inhibition of IL-11 signalling extends mammalian healthspan and lifespan. Nature
#FutMed Lok LSC, at al. Unlocking longevity: How blocking IL-11 signaling could extend healthspan and lifespan. doi.org/10.1002/mef2.101
@dbaptista @oliviamonteiro
ALT The potential of IL-11 inhibitors as antiaging therapies, coupled with AI-based biological age prediction and inflammatory, proteomic and epigenetic clocks offer promising avenues for promoting healthy aging and longevity.
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Perspective article in Medcomm-Future Medicine presents an analysis of the differences in clinical symptoms between 2022 #monkeypox outbreak and previous outbreaks. Less florid presentation may facilitate transmission.
💡Read more here
onlinelibrary.wiley.com/doi/…
Superb article. My group at the same time has published an analysis of clinical symptoms of current vs previous outbreaks. bit.ly/3V5ongb We have very similar findings - less florid and obvious symptoms may be masking the infected!
Super interesting stuff from the Moss lab and @neurorunner #neuroscience
New Research: Analyzing the mechanisms that facilitate the subtype-specific assembly of γ-aminobutyric acid type A receptors: Impaired inhibitory signaling underlies the pathophysiology of many neuropsychiatric and… frontiersin.org/articles/10.… #Molecular #Neuroscience
One, no, ten steps backwards... #AntibioticStewardship
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This finding is consistent with our report on Omicron specific neutralising antibody levels. nature.com/articles/s41392-0….
Using data from Brazil during the Omicron wave, a study in @NatureComms shows that boosters following a CoronaVac primary series provided protection against severe COVID-19, with higher effectiveness from a Pfizer booster than CoronaVac booster. go.nature.com/3MeNOIi
#EndStigmaAndDiscrimination Commission launch. Macau time Monday 10 Oct 1800 to 1930. Registration (free) link below. #WorldMentalHealthDay
This #WorldMentalHealthDay, join us for the launch of The Lancet Commission on Ending Stigma and Discrimination in Mental Health, hosted by @WHO.
Find out more and register 👉 bit.ly/3UCGlqq #EndStigmaAndDiscrimination
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New comment> #Monkeypox and the health-care environment thelancet.com/journals/lanmi…
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A new @CDCgov interim guidance outlines considerations for preventing and treating #monkeypox virus infections among people living with #HIV. ja.ma/3BRpXty #MedicalNews
Our research highlight on phylogenetic analysis of the #Monkeypox outbreak and the importance of sustained genetic surveillance. An all-MUST Faculty of Medicine production with @oliviamonteiro and one of our Year 4 MBBS student.
Timely and sustained sequencing efforts to track the potential evolutionary trajectory of #monkeypox virus is important to minimize its potential impact on global health. Learn more about the phylogenetic characterization of the #MPXV onlinelibrary.wiley.com/doi/…
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Our latest #chemobrain #biomarker study in @SciReports : We observed an association btw #estrogen precursors & declined cognitive function in breast cancer pts. Another step forward to understand the pathogenesis of #CRCI. rdcu.be/cWPHO @toh_long @chiajietan @UCI_SPPS
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Clinical trials using nonessential amino acids (#NEAAs) deprivation diet have shown positive outcomes in treating #cancers. In this review, possible mechanism and applications of NEAAs in diet deprivation therapy are summarized. #tumor #dietrestriction onlinelibrary.wiley.com/doi/…
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An artificial intelligence model was developed to predict the three-dimensional protein structures of #BDNF and #TrkB, as well as their interaction, which demonstrated a great potential for AI-enabled drug discovery for #glaucoma. #AI #DHF #RGCdegeneration onlinelibrary.wiley.com/doi/…
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A #bonetissueengineering approach with mesenchymal stem cell culture in aligned porous hydroxyapatite scaffolds using a multiwell plate bioreactor may overcome major clinical challenges of bone lost by trauma, diseases and #aging. #hWJMSC Learn more: onlinelibrary.wiley.com/doi/…
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Now live! First editorial from our Editors-In-Chief Profs. Robin Ali, Michael Karin, and @KangZhangMD: Announcing MedComm – Future Medicine: A forum to bring the future to the present. #multiomics #bioinformatics #medicalAI #regenerativemedicine #stemcell onlinelibrary.wiley.com/doi/…
MedComm-Future Medicine: A new open access journal publishing quality research in medicine and biology. Our stellar editorial team is led by Profs Robin Ali, Michael Karin and @KangZhangMD APCs are waived for the time being! Follow us @MedComm_FutMed
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Exciting news: I've been promoted to #professor. Humbled & overwhelmed by the support of peers & colleagues around the world, in particular a great group of people whose shoulders I stand on @Cag_Gi @Xing43872481 @_alicemain @Emzyne_ @Dilz39 @Liv__Robertson @NiallFraser7
Major funding success for research into chronic pain by my collaborator and good friend Prof. Tim Hales at Dundee.
dundee.ac.uk/stories/major-f…
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We are delighted to be top for Medicine in the @compuniguide alongside our good friends at @UofGlasgow 🎉🥳buff.ly/2ATwtUI @UoDMedicine #cugg2021