GP @nazarevc investing in AI infrastructure & compute | ex-Pantera Capital | Cambridge PhD | Essays on AI → https://xitter.cf/t.co/ldudEhUcuT

In the arena
Joined November 2006
We are investing in the "rebel alliance". DM me if you are building in this area.
Replying to @ccatalini
9/ Which is also why many are clamoring for a more open, resilient ecosystem, or even a rebel alliance: a handful of leading providers concentrates too much power — economic and political — in too few hands. xitter.cf/mignano/status/2066535…
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Back to the future
It is very important for the entire ai startup ecosystem for key inference vendors to be 1) capable of getting capacity that they can freely allocate, 2) secure, 3) reliable, 4) always driving cost and perf let’s not forget how much of an enabler cpu-era cloud was for innovation! no capex! outsource much of your infra ops (and more every year)! every small-mid customer “owning, building and running their own landed power, cooling qnd chips” completely ignores the lessons of economic history. we had colo 20y ago…public cloud won in an age where closed frontier labs weigh every (limited) GPU served by api vs. internal training and 1st party product use, inference abundance beyond them is a prerequisite for a rich startup ecosystem
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The whole “when will agents be autonomous and need identity and wallets” question reminds me of the DAO fiction which was peddled a few years ago in crypto circles. With DAOs we realized quickly that without real Legal standing DAOs were always inferior to a state’s company structure. In the same way we will quickly realize that agents need agency and that agency comes from people or companies. Autonomy is a fiction.
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Dr. Steven Waterhouse retweeted
So basically, today PHP got two critical bugs that let anyone run code on your server without even logging in, which is bad, and then the details leaked before the patch was even out, which is worse, and it works on WordPress and MediaWiki and Magento and Joomla and Laravel, and Censys says like 1.5 million servers are running a version with no fix, so the NSA was like "take your system offline," and the FBI was like "take your system offline," and CISA and the UK and CERT-EU were all like "take your system offline," and then the Prime Minister of Japan, the actual Prime Minister, posted at 5:55 in the morning telling 48.8 million people to take their system offline, so everyone took their system offline, like the Dutch cybersecurity agency took its own website offline, and the Dutch parliament went offline, and the Port of Rotterdam went offline, and Finland and France and Denmark started pulling government sites, and Wikipedia went down, and Archive.org went down, and Asana and GOG and Something Awful went down, and the University of Vienna's webmail went down for some reason, and that's just PHP. Because GitLab also dropped a CVSS 10.0, which is the highest score they give out, for a bug that's been there since 2014, so that's every self-hosted GitLab for twelve years, and then LiteLLM 1.107.0 got hijacked and shipped a credential stealer and a remote access trojan in every single wheel and the Docker images, including latest, and you didn't even have to import it, just installing it was enough, and it's the second time this year, and then Railway paused every deployment on the entire platform because someone got into the environment variables, so now everyone has to rotate every secret they've ever stored there, and TiDB Cloud said someone was walking around inside with stolen credentials for basically a month and an extortion group says they took 10.6 terabytes, and Zeabur got breached for the second time in two months and is just shutting down, like the whole company, and Node.js patched remote code execution and a TLS bypass, and CISA says Plex is being actively exploited, and someone took over 300 Tor exit relays to steal SSH passwords, and SafePay ransomware has hit over 600 critical infrastructure orgs, and India's biggest bank filed a data loss incident, and Japan has been in an official state of emergency in cyberspace since October 9, which honestly explains the 5:55 AM post. Oh, and eMudhra, a certificate authority that's issued over 60 million certificates, whose entire job is proving websites are who they say they are, was supposed to be using private keys that are random numbers over a hundred digits long, and one of them was 4. Just 4. And the others were like 66 and 237. Anyway, it's Wednesday.
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Congrats to @vast_ai and @PrimeIntellect @nazarevc portcos.
Fastest growing startups per Brex data
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Dr. Steven Waterhouse retweeted
The idea about leaving frontier AI to the US and China is wrong. Arthur is the only person in Europe doing what he’s doing and we respect that immensely. Tomorrow’s conversation will be on our most important to date.
BREAKING: Mistral Co-Founder and CEO Arthur Mensch (@arthurmensch) joins Luke and Ronan in The Arena at 1:15PM BST tomorrow.
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And then they came for the models
The Department of Homeland Security is requiring all civilian federal agencies to remove DeepSeek products and 'any third-party services developed using DeepSeek implementations,' and to stop buying them.
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Dr. Steven Waterhouse retweeted
Over two weeks, Prime Agent orchestrated a swarm of over 2,000 agents to rewrite itself in Rust. With 10,000+ sandboxes, 200B+ GLM-5.3 tokens, and 16,000 agent-to-agent messages, this was our largest test yet of Prime Agent’s multi-agent capabilities and our infrastructure powering these agent swarms. Prime Agent now reaches usable input ~13× faster and uses 83% less startup memory than before.
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Dr. Steven Waterhouse retweeted
OPEN CALL TO ROBOT DEPLOYERS. T-7 to our residency kickoff. Get hyped. Last chance to apply. Free robots, warehouse space, compute, software support, and connections to customers across data centers, agriculture, construction, manufacturing, real estate, more
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You will never have enough data or compute
a lot of people (rightfully) ask about the long-term value of data companies turns out building efficient, high-quality data pipelines is a science and a dark art unto itself. IMO, that's a big part of where the moat comes from really impressive to see what Proximal is building here
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Dr. Steven Waterhouse retweeted
Open superintelligence accelerates open scientific research. The Alzheimer’s Translation Challenge will share a 150M cell atlas on the Alzehimer's Disease workbench and Prima Mente's modeling platform. Prime Intellect is lending infrastructure support to researchers to build models based on this dataset. The best hypotheses will be tested in Prima Mente's wet lab.
Today we're launching the Alzheimer's Translation Challenge, a global AI competition to discover new therapeutic hypotheses for Alzheimer's disease. At its core is a new 150M cell atlas of neurons, astrocytes, and microglia across different genetic backgrounds under combinatorial perturbations, with multi-modal readouts. The data will be made available through the AD workbench, Hugging Face and Prima Mente's modeling platform. The challenge is led by @PrimaMente and @AlzData in collaboration with @nvidia, @huggingface, @nebiusai, Talisman Therapeutics, @UltimaGenomics, @cellanome, @PrimeIntellect, @GoodfireAI, and @boltz_bio. In 1906, Alois Alzheimer described a new disease of the brain. After 120 years of progress, we still don't fully understand what drives this disease. We want to change that. Participants will use the dataset to build AI models, assessed through a series of evals from general benchmarks to more complex tasks. Top teams will be shortlisted, and their experimental hypotheses tested in Prima Mente's wet lab. Teams win when their hypotheses demonstrate the predicted molecular and functional effect.
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Pearl is another chance for AI to hate crypto. Another miss
Follow-up: The manipulation is in the marketing. Let me be clear: I don't have anything against Pearl or the team. The cuPOW paper is high-quality research. But there is a massive gap between what the protocol actually does and what the shillers claim. Claim 1: "Proof of Useful Work" What they say: Pearl is a "Proof of Useful Work" network. The mining work is actually useful, it does AI inference. The cuPOW paper by Komargodski and Weinstein is the mathematical foundation for Pearl's mining. Its goal is to make sure that miners can't cheat by doing something too easy. The paper says the protocol should produce a "proof of work" that has "prescribed hardness" — meaning the work must be hard enough to be a real proof, and a miner can't find a shortcut that lets them win without doing the hard work. That part is about hardness. The work must be hard. It doesn't say the work must be useful. This prevents shortcuts like: Submitting all-zero matrices, Reusing pre-computed matrices, Exploiting low-rank or structured matrices that cost less than full n³ computation. The Key Distinction: Hardness vs. Utility Computational Hardness: The miner must do a lot of computation. They can't fake it or skip it. This is what the protocol guarantees. Computational Utility: The computation must produce something valuable like a real AI inference that someone actually needs. This is not guaranteed. The paper itself admits this. It says miners choose their own input matrices. The protocol only checks that the matrix multiplication was done correctly. It does not check that the matrices came from a real AI model or a paying customer. Usefulness is left as an "economic hope," not a cryptographic guarantee. The "usefulness" is supposed to come from economic incentives: miners with real AI customers would earn extra money, so they'd choose to do useful work. But loading real model weights costs more than generating random numbers. So the rational miner chooses the cheaper path: garbage mining. Claim 2: "Pearl has an AI inference lane" What they say: Pearl is a blockchain where mining is done as a byproduct of AI inference. What's actually happening: The AI inference isn't running on Pearl's network. It runs on Together AI's servers. Together AI is a separate company with its own GPUs. Pearl's miners don't run inference. They grind matrix multiplication on random numbers. Pearl's role is to subsidize Together AI's inference costs using PRL emissions. Together AI offers a 25% discount to its customers, and Pearl pays for that discount with newly minted PRL tokens. Claim 3: "Pearl is AI Bitcoin" What they say: Pearl is the "AI-native Bitcoin", a Bitcoin fork that uses AI computation instead of wasted hashing. What's actually happening: Pearl is a fork of Bitcoin's code. It swapped SHA-256 for matrix multiplication. That's it. There's no AI in the protocol. There's no inference. There's no model. There's no verification of useful work. The "AI" is a marketing layer. It's borrowed from a third party (Together AI). It's not native to Pearl. If Together AI disappeared tomorrow, Pearl would still mine matrices, but the "AI" narrative would vanish. Claim 4: "Duplex mining" (miners do AI inference + mining at the same time) What they say: The same GPU computation serves an AI customer and mines Pearl blocks. Two rewards for one job. What's actually happening: The protocol cannot tell if a miner is doing inference or just grinding random matrices. It only verifies that a matrix multiplication was done correctly. It doesn't verify that the matrices came from a real model. So a rational miner will skip the inference and submit random matrices. Loading model weights costs memory I/O. Generating random numbers is cheaper. The "duplex" part is optional. The Pass paper (Pearl's own economic defense) admits in its own text that pure mining is 23% cheaper than duplex mining. And here's the part nobody talks about: the so-called duplex mining doesn't secure the chain while doing AI. Even if a miner somehow did both ran real inference and mined a block the protocol still wouldn't verify that the inference happened. The block is secured by the matrix multiplication, not by the inference. The AI work is parallel to the mining, not part of it. The AI happens on Together AI's servers. The mining happens on Pearl's network. The two are linked only by a financial subsidy , PRL emissions paying for a discount on Together AI's inference. There's no cryptographic connection between them. So "duplex mining" isn't securing the chain with AI. It's securing the chain with matrix multiplication while AI happens somewhere else entirely. The "duplex" is a billing arrangement, not a consensus mechanism. pearl-2:native should be called "Proof of Computational Hardness." That's what the paper guarantees, what the network enforces, and what the miners actually produce. "Proof of Useful Work" and "AI native Bitcoin" are marketing terms, not protocol features. The Bubble Is Built on an Assumption The shillers are selling a narrative the protocol doesn't support. They assume miners will choose useful work out of economic incentive. But the protocol doesn't enforce it. And when the cheaper path is always available, rational miners take it. The bubble is this: a token whose value depends on "useful work" that the protocol cannot verify. When the gap becomes obvious and the Cornell study already made it obvious, the narrative bursts. And who's left holding the bag? The shillers who sold the story, and the retail who bought it. "The pigeon saw the cat. Then it closed its eyes. There are none so blind as those who will not see."
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Dr. Steven Waterhouse retweeted
Post-training / RL and inference is taking over compute
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Classic
I told Claude to make a video about what it's like to be European One day later...
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Replying to @PrimeIntellect
Extropic designed the tasks and the reward, while Prime Intellect handled the RL infrastructure: 1. verifiers to build the environment 2. Hosted Training to run the RL loop 3. Prime Sandboxes to execute the model's code and return the execution score 4. Prime Inference to serve the LLM judge and frontier baselines
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