I think this was part of the implicit premise of the first incarnation of Hammer Lab at Mount Sinai, about a dozen of us with math/CS backgrounds ditched tech for biomedicine. And we got humbled hard: most of what we did flopped & techies don't understand experimental design.

But it's a big tell that someone hasn't really ever grappled with the difficulties of actually making a confident discovery from biological messiness to think that the missing ingredient is people who took more signal processing classes or imbibed more essays on tech startups.