@dtleffa

MD-PhD, researcher in ADHD, Psychiatry resident @PittPsychiatry

Joined February 2020
  • Tweets146
  • Following368
  • Followers315
3Media
Douglas Leffa retweeted
Pascoal Lab@LabPascoal26 Jul 2024
Looking forward to the Pascoal team’s presentations at this Saturday’s #AIC pre-conference! @NeuroimagingPIA @ISTAART @alzassociation Check out our line-up: – at Philadelphia, PA
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Douglas Leffa retweeted
Pascoal Lab@LabPascoal27 Jul 2024
Congratulations to @BellaverBruna for receiving the Publication of the Year Award from the Biofluid Based Biomarkers @ISTAART Professional Interest Area at PIA day, for her recent paper in Nature Medicine! #AAIC24 – at Philadelphia, PA
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Very proud to share this one! Here we showed transcriptomic similarities and differences between three AD animal models and EOAD and LOAD. Thank you all to collaborators involved @giovannacollar @erzimmer @mvlourenco @aslfricardo @TharickAPascoal @pedrorosaneto
Zimmer Lab@zimmerneurolab19 Jan 2024
🚨ONLINE NOW! In our new article led by @BellaverBruna and #DeBastiani published in @iScience_CP, we took advantage of comparative medicine tools to investigate molecular core similarities and differences among AD mouse models and EOAD and LOAD individuals tinyurl.com/3fj8b8tb
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Please join us in welcoming new faculty members Bruna Bellaver, PhD (Research Assistant Professor of Psychiatry), and Pamela Lukasewicz Ferreira, PhD (Research Assistant Professor of Psychiatry)! bit.ly/3SeYaNE
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Research from Pitt's School of Medicine may hold the key to understanding Alzheimer's progression. Read more about this groundbreaking study. pittmag.pitt.edu/news/advanc…
A tall brown-skinned man stands next to a shorter white woman with long hair. They both wear medical white coats. Medical brain scans are in the background.

ALT A tall brown-skinned man stands next to a shorter white woman with long hair. They both wear medical white coats. Medical brain scans are in the background.

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A link between #ADHD and #Alzheimers disease has been suspected for some time, and now two separate #research studies have shown a #connection. Find out more ➡️ bit.ly/3KrQnHD.
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What an amazing experience at #AAIC23! Thanks a lot for the @alzassociation @ISTAART for the opportunity to share our work from @LabPascoal 🇺🇸 & @zimmerneurolab 🇧🇷. Already excited to see you all again in Philly #AAIC24 🧠
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Douglas Leffa retweeted
Pascoal Lab@LabPascoal31 Jul 2023
We are happy that @dtleffa's work linking ADHD with Alzheimer's is being featured in numerous TV broadcasts across the country, reaching millions of Americans wgem.com/2023/07/24/brain-co…

Brain connection: ADHD & Alzheimer’s link?

More than six and a half million people are living with Alzheimer’s in the United States.

wgem.com
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Douglas Leffa retweeted
Pascoal Lab@LabPascoal12 Jul 2023
We thank the @alzassociation and are very proud of our postdocs @gbnegrini and @SarahAbbas52 awarded with the AA Research and Clinical fellowships, respectively. They will address important gaps in tau PET harmonization and the use of inflammation biomarkers in trials. Congrats!!
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Douglas Leffa retweeted
Pascoal Lab@LabPascoal16 Jul 2023
What a fantastic talk by @guilhermepovala at #AIC23, where he discussed the impact of microglial activation on brain atrophy in preclinical AD. #AAIC2023 @alzassociation @ISTAART
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Douglas Leffa retweeted
Pascoal Lab@LabPascoal17 Jul 2023
During the coffe break don’t miss the opportunity to check the beautiful poster of @FrancieliRohden where she evaluated the association between astrocyte reactivity and synaptic distinction!! #AAIC2023 @alzassociation
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Douglas Leffa retweeted
Pascoal Lab@LabPascoal18 Jul 2023
Fantastic presentation by @dtleffa where she showed that the individuals with ADHD and cognitive impairment may have a more severe disease phenotype. #AAIC2023
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Douglas Leffa retweeted
Pascoal Lab@LabPascoal29 Mar 2023
This morning @BellaverBruna presented her results on how kidney function impacts plasma p-tau levels, mainly in cognitively unimpaired individuals. If you missed it, her presentation is also available on-demand! @adpdnet #ADPD2023 #adpd23
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Douglas Leffa retweeted
Pascoal Lab@LabPascoal29 Mar 2023
@BellaverBruna work "BLOOD-BRAIN BARRIER PERMEABILITY IMPACTS THE PERFORMANCE OF PLASMA AMYLOID-B" can be found in the poster hall by the number 329.#ADPD2023 @adpdnet
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Douglas Leffa retweeted
Pascoal Lab@LabPascoal1 Apr 2023
This afternoon @FrancieliRohden gave a great talk showing that synaptic dysfunction is associated with GFAP, independent of amyloid beta and tau pathologies. #ADPD2023 @adpdnet
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Douglas Leffa retweeted
Pascoal Lab@LabPascoal1 Apr 2023
Closing the talks of our group on #ADPD2023 @dtleffa gave a fantastic talk showing that in CU older adults, higher genetic risk for ADHD was associated with longitudinal cognitive decline, as well as increased CSF tau levels and frontoparietal atrophy. @adpdnet
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We are delighted to announce that Tharick Pascoal, MD, PhD, has been promoted to Associate Professor of Psychiatry by the University of Pittsburgh School of Medicine! bit.ly/3lTX8Zu
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Douglas Leffa retweeted
Pascoal Lab@LabPascoal20 Mar 2023
We're excited because it's almost time to travel to Gothenburg for #ADPD2023! Please stay tuned and save time to check out our oral and poster presentations @adpdnet #ADPD202! pascoallab.org
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Douglas Leffa retweeted
Pascoal Lab@LabPascoal15 Mar 2023
New paper alert: @BellaverBruna showed in 2 independent cohorts that individuals with increased BBB integrity present a better association between brain and plasma Aβ levels which might help explain the variability found in some plasma Aβ studies/assays. tinyurl.com/3uwacykp

Blood‐brain barrier integrity impacts the use of plasma amyloid‐β as a proxy of brain amyloid‐β...

INTRODUCTION Amyloid-β (Aβ) and tau can be quantified in blood. However, biological factors can influence the levels of brain-derived proteins in the blood. The blood-brain barrier (BBB) regulates...

alz-journals.onlinelibrary.wiley.com
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!!! WE ARE HIRING !!! Come and work with us on a very ambitious large-scale EU funded project on prediction modelling in @autism jobs.soton.ac.uk/Vacancy.asp… @SotonPsych @UoS_Medicine @RcpsychCAP
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