Dinesh Gupta (@electro_microbe) profile picture

Dinesh Gupta

@electro_microbe

PhD @WUSTL I Postdoc @UCberkeley @berkeleyMCB - Archaeal/bacterial genetics and physiology, c-type cytochromes, extracellular electron transfer

Joined July 2019
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Dinesh Gupta retweeted
Nayak Lab (@lab_nayak) profile picture
Nayak Lab@lab_nayak29 Oct 2024
🚨 Our stellar postdoc (w/ Stolper Lab) @GroppJonathan posted his first preprint! His work resolves a long-standing conundrum in the field of geobiology by showing how the biochemistry of methanogenesis impacts the isotope composition of biogenic methane! biorxiv.org/content/10.1101/…
CRISPR-enabled control of gene expression sets the isotopic composition of microbial methane

CRISPR-enabled control of gene expression sets the isotopic composition of microbial methane

The stable isotopic composition of biogenic methane varies substantially in the environment and is routinely used to fingerprint its source. However, the underlying cause of this variation is...

biorxiv.org
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Super happy to see our work on MmcA, a multiheme cytochrome c from the model methanogen, Methanosarcina acetivorans is out today. A big thanks to @lab_nayak, @Keyiiiiing and @Prof_SJE !!!
Nayak Lab (@lab_nayak) profile pictureNayak Lab@lab_nayak17 Apr 2024
So excited to have this ⚡️electrifying⚡️ story published! Congratulations to lead author Dinesh (@electro_microbe) & collaborators! @lab_sje Check out the article to learn about the roles of MmcA in methanogenic electron transport: nature.com/articles/s41467-0…
MmcA is an electron conduit that facilitates both intracellular and extracellular electron transp...

MmcA is an electron conduit that facilitates both intracellular and extracellular electron transp...

Nature Communications - Methanogens conserve energy through methane generation, however the biochemical details of anaerobic respiration in methanogens remain unclear. Here, authors show a...

nature.com
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So happy to see my postdoc advisor @lab_nayak among the Sloan Research Fellowship recipient this year. Very well deserved! Congratulations!!!
Nayak Lab (@lab_nayak) profile pictureNayak Lab@lab_nayak20 Feb 2024
We're SO excited for and proud of our PI Dr. Nayak for this achievement!!! 🥳👩‍🔬 Congratulations to all the other Sloan Research Fellows at UC Berkeley and beyond! 🎊🥼🧪 news.berkeley.edu/2024/02/20…
Nine young faculty members receive prized Sloan Research Fellowships - Berkeley News

Nine young faculty members receive prized Sloan Research Fellowships - Berkeley News

As a sign of the University of California, Berkeley’s ability to attract the most promising early-career researchers, nine young assistant professors have been named 2024 Sloan Research Fellows, the...

news.berkeley.edu
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Dinesh Gupta retweeted
Nayak Lab (@lab_nayak) profile picture
Nayak Lab@lab_nayak14 Dec 2023
Methanogens ❤️ MCR, but how much do they really need? 🤔 Our postdoc Gray Chadwick & grad student Gavin Dury titrated MCR expression to test the hypothesis that MCR catalyzes the growth rate-limiting step of methanogenesis in their new preprint! 🤓 Read: biorxiv.org/content/10.1101/…
Physiological and transcriptomic response to methyl-coenzyme M reductase limitation in Methanosar...

Physiological and transcriptomic response to methyl-coenzyme M reductase limitation in Methanosar...

Methyl-coenzyme M reductase (MCR) catalyzes the final step of methanogenesis, the microbial metabolism responsible for nearly all biological methane emissions to the atmosphere. Decades of biochemi...

biorxiv.org
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Dinesh Gupta retweeted
Nayak Lab (@lab_nayak) profile picture
Nayak Lab@lab_nayak13 Jun 2023
Thrilled to share that our paper on MCR assembly was published @PNASNews: pnas.org/doi/epdf/10.1073/pn…
Nayak Lab (@lab_nayak) profile pictureNayak Lab@lab_nayak4 Feb 2023
So proud to share the newest pre-print from our lab: biorxiv.org/content/10.1101/… A tour de force co-led by postdocs Gray and Aaron @aaronjoinerphd, in collaboration with Sangeetha Ramesh and Prof. Doug Mitchell at UIUC. Turns out it takes a village to do great science (& build MCR!)
McrD binds asymmetrically to methyl-coenzyme M reductase improving active site accessibility during...

McrD binds asymmetrically to methyl-coenzyme M reductase improving active site accessibility during...

Methyl-coenzyme M reductase (MCR) catalyzes the formation of methane and its activity accounts for nearly all biologically produced methane released into the atmosphere. The assembly of MCR is an...

biorxiv.org
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Dinesh Gupta retweeted
WUSTLnews (@WUSTLnews) profile picture
WUSTLnews@WUSTLnews5 May 2023
Congratulations to Ursula W. Goodenough, a professor emerita of biology, and William B. McKinnon, a professor of earth and planetary sciences, both in @WUSTLArtSci. They have been elected to the National Academy of Sciences. bit.ly/3HIhzR0
Goodenough, McKinnon elected to National Academy of Sciences

Goodenough, McKinnon elected to National Academy of Sciences

Ursula W. Goodenough, a professor emerita of biology, and William B. McKinnon, a professor of earth and planetary sciences, both in Arts & Sciences at Washington University in St. Louis, have been...

source.washu.edu
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Dinesh Gupta retweeted
Nayak Lab (@lab_nayak) profile picture
Nayak Lab@lab_nayak22 Apr 2023
TGIF! A new preprint out from our superstar postdoc @electro_microbe w/ collabs @Keyiiiiing & @lab_sje! Our fave heptaheme cytochrome, MmcA, takes the stage to tell us more about its role in e- transport to membrane bound & extracellular acceptors! biorxiv.org/content/10.1101/…
MmcA is an electron conduit that facilitates both intracellular and extracellular electron transp...

MmcA is an electron conduit that facilitates both intracellular and extracellular electron transp...

Methanogens are a diverse group of Archaea that couple energy conservation to the production of methane gas. While most methanogens have no alternate mode of energy conservation, strains like...

biorxiv.org
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🚨New Preprint Alert!🚨 Interested in #Archaea #MHCs #EET and Energy conservation. Check out our recent findings! I greatly appreciate and am thankful to my wonderful PI @lab_nayak and for the incredible collaboration with @Keyiiiiing and @Prof_SJE ! biorxiv.org/content/10.1101/…
MmcA is an electron conduit that facilitates both intracellular and extracellular electron transp...

MmcA is an electron conduit that facilitates both intracellular and extracellular electron transp...

Methanogens are a diverse group of Archaea that couple energy conservation to the production of methane gas. While most methanogens have no alternate mode of energy conservation, strains like...

biorxiv.org
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I had a wonderful time at the #NorCalGeobio symposium meeting great researchers and learning about their cool sciences. Thanks to the organizers!!!
Anne Dekas (@annedekas) profile pictureAnne Dekas@annedekas16 Apr 2023
105 attendees, 60 presentations, 22 institutes - the 1st #NorCalGeobio symposium rocked! 😆 CONGRATS to the amazing student/postdoc presenters, esp. the 1st timers, and THANKS to the awesome student organizers. See you next year! @amanda_semler @pulkitsingh97 @NSF @stanforddoerr
Image from Anne Dekas (@annedekas)
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Dinesh Gupta retweeted
Anne Dekas (@annedekas) profile picture
Anne Dekas@annedekas16 Apr 2023
105 attendees, 60 presentations, 22 institutes - the 1st #NorCalGeobio symposium rocked! 😆 CONGRATS to the amazing student/postdoc presenters, esp. the 1st timers, and THANKS to the awesome student organizers. See you next year! @amanda_semler @pulkitsingh97 @NSF @stanforddoerr
Image from Anne Dekas (@annedekas)
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Dinesh Gupta retweeted
Nayak Lab (@lab_nayak) profile picture
Nayak Lab@lab_nayak4 Feb 2023
So proud to share the newest pre-print from our lab: biorxiv.org/content/10.1101/… A tour de force co-led by postdocs Gray and Aaron @aaronjoinerphd, in collaboration with Sangeetha Ramesh and Prof. Doug Mitchell at UIUC. Turns out it takes a village to do great science (& build MCR!)
McrD binds asymmetrically to methyl-coenzyme M reductase improving active site accessibility during...

McrD binds asymmetrically to methyl-coenzyme M reductase improving active site accessibility during...

Methyl-coenzyme M reductase (MCR) catalyzes the formation of methane and its activity accounts for nearly all biologically produced methane released into the atmosphere. The assembly of MCR is an...

biorxiv.org
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Preprint Alert! 🚨Check out this incredible work by our superbly talented postdoc and wonderful colleague, Dr. Grayson Chadwick, from @lab_nayak showing the role of McrD in the assembly and installation of F430 to the enzyme Methyl-coenzyme M reductase. biorxiv.org/content/10.1101/…
McrD binds asymmetrically to methyl-coenzyme M reductase improving active site accessibility during...

McrD binds asymmetrically to methyl-coenzyme M reductase improving active site accessibility during...

Methyl-coenzyme M reductase (MCR) catalyzes the formation of methane and its activity accounts for nearly all biologically produced methane released into the atmosphere. The assembly of MCR is an...

biorxiv.org
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New Research paper Alert!🚨 Interested in #Archaea #Methanogen #Methanemetabolism #MHC (multiheme cytochrome c), Check out the new findings by our incredible PhD candidate @blkdwnng from @lab_nayak. Congratulations Blake!
Nayak Lab (@lab_nayak) profile pictureNayak Lab@lab_nayak23 Jan 2023
Huge congratulations to @blkdwnng on his first, first author publication! We are so proud of you-- Rnf actually stands for "Really Nice First (publication)"😎 Also congrats to co-author @electro_microbe!! Out now in @MolMicroEditors; read it here: onlinelibrary.wiley.com/doi/… ⚡️🦠
The dual role of a multi‐heme cytochrome in methanogenesis: MmcA is important for energy conserva...

The dual role of a multi‐heme cytochrome in methanogenesis: MmcA is important for energy conserva...

In this study, we use genetic techniques to characterize the in vivo function of the Rhodobacter nitrogen fixation complex (Rnf) and the associated multi-heme c-type cytochrome MmcA in the model...

onlinelibrary.wiley.com
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We're so excited for a fellow #chlamy -ologist, Ursula Goodenough. She has a new book,"Sacred Depths of Nature", that can be preordered via Oxford University Press or Amazon with more info in this link: sacreddepthsofnature.com/inf…. It's set to be released in Feb 2023. Congrats!
Ursula Goodenough, biologist

ALT Ursula Goodenough, biologist

Image from S. Merchant Lab (@Merchant_Lab)
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Check out new findings by our brilliant graduate student @blkdwnng from @lab_nayak, suggesting new role to our favorite multiheme cytochrome c, MmcA.
Nayak Lab (@lab_nayak) profile pictureNayak Lab@lab_nayak21 Jul 2022
🚨 New pre-print from our lab for fans of microbial metabolism! 📑⚡️ It's got growth curves galore and some hypotheses about backup pathways for ferredoxin regeneration. Congratulations to @blkdwnng (his 1st 1st author!) @electro_microbe and Dr. Nayak! biorxiv.org/content/10.1101/…

The dual role of a multi-heme cytochrome in methanogenesis: MmcA is important for energy conserva...

Methanogenic archaea belonging to the Order Methanosarcinales conserve energy using an electron transport chain (ETC). In the genetically tractable strain Methanosarcina acetivorans , ferredoxin...

biorxiv.org
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#Methanogenic #archaea #methanogens #anaerobiosis #methane #Methanosarcina
eLife - the journal (@eLife) profile pictureeLife - the journal@eLife13 May 2022
Single celled, methane-producing Archaea generate nearly 70% of the methane gas released into the atmosphere. Insights into the role of c-type cytochromes may reveal how. elifesciences.org/digests/76…

Methane makers

New insights about key biological processes in methane-producing organisms called Archaea may have implications for understanding their role in climate change.

elifesciences.org
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Interested in learning more about Cytochrome c, Methanogenic Archaea, and Methanogenesis, check out this cool story!
eLife - the journal (@eLife) profile pictureeLife - the journal@eLife13 May 2022
Single celled, methane-producing Archaea generate nearly 70% of the methane gas released into the atmosphere. Insights into the role of c-type cytochromes may reveal how. elifesciences.org/digests/76…

Methane makers

New insights about key biological processes in methane-producing organisms called Archaea may have implications for understanding their role in climate change.

elifesciences.org
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Dinesh Gupta retweeted
Nayak Lab (@lab_nayak) profile picture
Nayak Lab@lab_nayak5 Apr 2022
Presenting our lab's first research article: elifesciences.org/articles/7…. This work marks a tour de force by two incredible scientists @electro_microbe and @KShalvarjian. Congrats!!
An Archaea-specific c-type cytochrome maturation machinery is crucial for methanogenesis in...

An Archaea-specific c-type cytochrome maturation machinery is crucial for methanogenesis in...

A streamlined form of the bacterial System I cytochrome c biogenesis machinery in archaea was characterized using Methanosarcina acetivorans as a model system.

elifesciences.org
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I’m very excited to share our new eLife paper on cytochrome c biogenesis in Archaea. Thanks to my wonderful PI Dipti Nayak @lab_nayak and fantastic colleague @KShalvarjian elifesciences.org/articles/7…
An Archaea-specific c-type cytochrome maturation machinery is crucial for methanogenesis in...

An Archaea-specific c-type cytochrome maturation machinery is crucial for methanogenesis in...

A streamlined form of the bacterial System I cytochrome c biogenesis machinery in archaea was characterized using Methanosarcina acetivorans as a model system.

elifesciences.org
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