Bub lab site, Physiology Dept, McGill University.

Montréal, Québec
Joined January 2017
Very cool indeed! It was great to be part of this effort. Thank you @victor__badillo and all the other co-authors 🎉
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Portable low-cost macroscopic mapping system for all-optical cardiac electrophysiology in JBO - work by postdoc Yuli Heinson and PhD student Julie Han. One of two technology development papers. Highlighted by SPIE spiedigitallibrary.org/journ…
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We present rapid projection imaging under variable viewing angles. We apply this method in light-sheet and spinning disk microscopy to visualize 3D samples in real time. We further demonstrate that 3D information can be gathered from a set of projections. nature.com/articles/s41592-0…
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ChR2 cell spheroids were manufactured, cryopreserved, thawed and successfully deployed for cardiac pacing; integration was faster than it takes to genetically modify the cardiac cells.
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Join us on Thursday 17 June, 6-7pm to hear from @GaryMirams. His lecture on Mathematical Matters of the Heart will explain how simulations are assessing the safety of new medicines. Open to all, booking required. scipubliclecturejune21.event…
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Replying to @Maurice_Y_Lee
Alternative implementations are available! At @UniofExeter we replace the reflector with a smaller transmissive lens to study the feeding habits of sea worm larvae (different food stock in each well). Credit: @MarInvMet and BSc student Natalie Wood.
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Sorcery!
Are you struggling to image multiple samples at the same time? A new high-throughput imaging system allows parallel imaging in a 96-well plate! Which dynamic process would you image? elifesciences.org/articles/5…
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Are you struggling to image multiple samples at the same time? A new high-throughput imaging system allows parallel imaging in a 96-well plate! Which dynamic process would you image? elifesciences.org/articles/5…
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Most imaging objectives try to minimise chromatic aberration. In this paper we exploit it to provide wavelength-dependent refocusing of brightfield images. DOI: 10.7554/eLife.56426
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It was fun working on this review with Matt @mwkaylab, covering the opportunities #optogenetics has brought to the #heart since 2010, when first used by @huiskenlab, P. Sasse, T. Bruegmann, O. Abilez, D. Pijnappels and several other labs including mine.
New #Review! #Cardiac #optogenetics: A decade of enlightenment. @emilia_entcheva and @mwkaylab discuss important developments and applications of optogenetics to the #heart, focusing on clinical translation of this technology in #cvd and #cardiology. rdcu.be/ccxqX
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We are excited to announce the NOTICE2020 webinar! On Friday August 28th join us for three fantastic talks by Gil Bub, Chris Xu and Ahmed Abdelfattah. You can register for free via our Eventbrite page: eventbrite.co.uk/e/notice202…
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This is very important - whole organ imaging at more than video rate 7 light sheets synchronised to SEE an action potential in a whole zebrafish heart. @simoesfili think how to use this @gilbublab is waiting
Fast live imaging of action potential propagation in zebrafish heart loaded with voltage sensitive dye using SPEED microscopy: multiple parallel light-sheets (7 here) with dedicated cameras, no z-scan needed. Gil Bub @McGillPhysioloG @LeonardoSacconi biorxiv.org/content/10.1101/…
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Gil Bub retweeted
KHz-rate volumetric voltage imaging of the whole zebrafish heart biorxiv.org/content/10.1101/… AP propagation through whole heart volume imaged with di-4-ANBDQPQ potentiometricprobes.com/di-… @VSDexperts @LeonardoSacconi @gilbublab
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Fast live imaging of action potential propagation in zebrafish heart loaded with voltage sensitive dye using SPEED microscopy: multiple parallel light-sheets (7 here) with dedicated cameras, no z-scan needed. Gil Bub @McGillPhysioloG @LeonardoSacconi biorxiv.org/content/10.1101/…
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Gil Bub retweeted
Excellent talks and great interactions with our colleagues from Ox and McGill on Day 1 of the first Oxford-McGill Biophotonics Networking Meeting @DPAGAthenaSwan. Supported by @mcgillu, @OxNeuro, @Thorlabs, @Cairn_Research and @coolLEDltd.
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