Neurobiologist, professor, @Univ_Paris Interested by brain devt and plasticity in its various forms. Co-chair https://teapawt.net/t.co/r0iTvHKRBJ
Paris, France, IBPS, Jussieu
Joined March 2017
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@elife Final version : see how FMRP regulates neuronal migration via MAP1B ! 🤝 doi.org/10.7554/eLife.88782
#neuronalmigration #FMRP #MAP1B
Have a look in case you missed over the weekend. 🧐 Disruted nuclear micropubular cage - disrupted migration!
@elife Final version : see how FMRP regulates neuronal migration via MAP1B ! 🤝 doi.org/10.7554/eLife.88782
#neuronalmigration #FMRP #MAP1B
Isabelle Caillé retweeted
#Review alert! Thrilled to share our new review in Trends in Neuroscience on #cilia in neurons where we dive into cilia diversity and signaling in the sensory and central nervous system. sciencedirect.com/science/ar…
Isabelle Caillé retweeted
@marcosanascim and I put together a short summary of our recent paper that includes some of our favorite highlights and a few further thoughts about the implications of the finding: nature.com/articles/d41586-0…
Totally new vista onto FXS! Heterochromatinization of synaptic genes in trans. Read the 🧵
(Not new but I missed it!)
Spatially coordinated heterochromatinization of long synaptic genes in fragile X syndrome: Cell cell.com/cell/fulltext/S0092… Amazing paper showing that CGG repeat expansion causes heterochromatin assembly at FMR1, but also a plethora of other genes in TRANS!
Isabelle Caillé retweeted
How does the competence of GABAergic progenitors change in time? It depends on whether you're looking at maturation or differentiation! Check out our new preprint: doi.org/10.1101/2024.03.18.5…
Big shoutout to the amazing contributors, esp. @YanaKotlyarenk1 @annrosebright8, Flo, Diana!
Isabelle Caillé retweeted
Another gem from the Hiesinger lab👇🏽
Axonal self-sorting without target guidance in Drosophila visual map formation | Science science.org/doi/10.1126/scie…
Isabelle Caillé retweeted
This is pretty amazing: a single hominoid-specific genetic change leads to loss of the tail. What an incredible phenotype!
How did we lose our tail? A simple question.. but it wasn't really asked before! We discovered a plausible scenario for the genetic mechanism that led to tail loss. Amazing that such a big change may have been caused by such a small genetic event. nature.com/articles/s41586-0… @BoXia7
A vot bon coeur messieurs dames... 🙏🙏🙏
lemonde.fr/societe/article/2…
What is tout opinion about that?
As a French person, I will definitely use ChatGPT to improve my English on a first personal draft. It seems fair to me as it is proven that non native English scientists are disadvantaged in high profile Journals...
A journal reviewer accused Lizzie Wolkovich of using ChatGPT to write a manuscript. She hadn’t — but her paper was rejected anyway go.nature.com/48pFU8q
Isabelle Caillé retweeted
Preprint alert! In two complementary studies, we show that in vivo tissue mechanics regulates chemical signalling for both soluble and membrane-bound ligands. #mechanics and #biochemistry are intimately linked! #mechanobiology #Xenopus #brain @PDN_Cambridge @UniFAU @EBM_research
Isabelle Caillé retweeted
Hey y'all, check out the latest from my better half's lab.....this type of work makes it possible to eventually get a spritz of Lyme vaccine. Appreciate any RTs to spread the word 🙏 #lymedisease #vaccine
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A retroviral origin of myelin!
cell.com/cell/fulltext/S0092…
Isabelle Caillé retweeted
Mechanics in the nervous system: From development to disease: Neuron cell.com/neuron/fulltext/S08…
Isabelle Caillé retweeted
Super excited to see our work on foxj1 and olfactory sensory neurons out in @PLOSBiology. Tweetorial to come soon! In the meantime enjoy this gorgeous pictures of the zebrafish olfactory system taken by @EgeMertege6
How are olfactory #cilia and sensory neuron differentiation regulated? This study of #zebrafish & mice shows that the #forkhead domain transcription factor Foxj1 is critical for #OlfactoryCilia and #SensoryNeuron differentiation #PLOSBiology plos.io/3SfsTbv
ALT Two zebrafish, with Foxj1b-positive cells stained.
Isabelle Caillé retweeted
We are hiring!
We are currently hiring a talented and highly motivated postdoctoral researcher for a 2-year position on primary cilia and brain development in health and disease.
candidate.hr-manager.net/App…
Isabelle Caillé retweeted
Meanwhile, in the world of weird mechanisms of #protist locomotion...
doi.org/10.1016/j.cub.2023.1…
(note the need to generate oscillatory movement)
Introducting Meteora sporadica, a most weird and wonderful protist: authors.elsevier.com/c/1iTUX…
Isabelle Caillé retweeted
Today in @Nature, researchers led by Arturo Alvarez-Buylla, PhD, & @shawn_sorrells show that significant numbers of new neurons migrate into the human entorhinal cortex, a brain region that is crucial for memory-related functions, until 2-3 years of age: nature.com/articles/s41586-0…
A brand new postnatal stream of migration to the temporal lobe of young children! Wouaouh! 👏👏👏
nature.com/articles/s41586-0…
Reviewed preprint @eLife online!
Very happy with the fast reviewing and the whole process!
#FMRP #MAP1B #Neuronalmigration #FXS
doi.org/10.7554/eLife.88782.…
Version of Record soon to resubmitted with lots of improvement and a direct microtubular link for the FMRP/MAP1B duo in migrating neurons: stay put. 🥳
#eLife really displays a
disrupting review process!
elifesciences.org/peer-revie…
Isabelle Caillé retweeted
3 postdoc position available in @TheHassanLab:
1- Biologist to model non-coding human neurodevelopmental disorders
2- Bioinformatician specialised in genomic data analysis
3- Biologist to study the link between neuronal diversity and function in Drosophila
details👇. Please RT.
