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Evolution. AI-Native Discovery. Therapeutics.

Boston
Joined March 2026
Photo by Intertwined Biosciences (@intertwinedbio)
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What if the animals around us already solved some of medicine’s hardest problems? Horses rarely get liver cirrhosis. Naked mole rats live far longer than other rodents. Bowhead whales can survive for over 200 years. Some organisms withstand radiation that would destroy human cells. On this episode of Galaxy Balance, I speak with Max Rye and Evan Appleton, cofounders of Intertwined Bio, about using evolution as a design library for human health. We explore how extreme traits from nature could be translated into therapies for liver fibrosis, DNA damage, aging, immune dysfunction, and even the future of humans in space. This is synthetic biology at the edge of science fiction. Biology has already invented extraordinary resilience. Now the question is whether we can learn to engineer it.
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Intertwined Biosciences is out of stealth 🚀 We're harnessing evolution to build regenerative therapeutics using AI-native discovery. Just admitted to @LabCentral AI BioHub w/ @C10Labs. First experiments live. Raising pre-seed. DM if you're at the intersection of AI x bio
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