farm kid turned PhD candidate in @kristyredhorse lab | NSF GRFP Fellow | #FGLI | 🏳️🌈 (he/him) | working on:🤰🏻🔬🫀🧬🐭 🧫
Stanford, CA
Joined March 2023
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A wonderful past two weeks, presenting my work at the 10th Anniversary @HHMIJanelia / @embl Imaging Mouse Development Conference, submitting the DP5, and doing plenty of hiking after turning the big 3-0 and celebrating with a visit from my mom! Onto the best decade yet!
James Zwierzynski retweeted
The Koh Lab at Yale School of Medicine is hiring! We are recruiting motivated post-graduate associates, graduate students and post-doctoral fellows to join us on our exciting exploration of specialized bone marrow niches in craniofacial bones!
medicine.yale.edu/profile/bo…
Looking to join a collaborative team studying coronary artery development? Love taking pretty microscope images? The Red-Horse lab (@hhmi_science/@Stanford) is hiring for a senior scientist to research coronary & collateral artery development apply below!:
tinyurl.com/5d85xjze
James Zwierzynski retweeted
Why do guinea pigs have so many natural bypass arteries?
In our preprint, we use this ischemia-resistant mammal + in vivo Perturb-seq to ask how protective collateral arteries are built.
The surprise: more collaterals may come from turning down “artery repressor” pathways, including WNT, hypoxia-response, and TCA cycle.
Knocking down selected repressors increased pial collaterals in mouse brain.
@RonghaoZhou @kristyredhorse @jengreitz @BRaftrey @PamR33 @ChenMaggieSY
biorxiv.org/content/10.64898…
James Zwierzynski retweeted
If this work is interesting to you, we're hiring for a Senior Scientist with post-doctoral experience and a background in RNA molecular biology or whole organ imaging and analysis to join our small, collaborative team!
Apply here: careersearch.stanford.edu/jo…
Excited to share our preprint, reviving @kristyredhorse's interest in the placenta from her PhD ~20 years ago! We find using 3D imaging that the mouse placenta is far more invasive than previously thought. Furthermore, we find a surprise from our favorite chemokine CXCL12...🧵:
Excited to share our preprint, reviving @kristyredhorse's interest in the placenta from her PhD ~20 years ago! We find using 3D imaging that the mouse placenta is far more invasive than previously thought. Furthermore, we find a surprise from our favorite chemokine CXCL12...🧵:
3D imaging of the pregnant uterus reveals an extensively invasive mouse placenta requiring CXCL12-CXCR4 signaling biorxiv.org/content/10.64898… #biorxiv_devbio
We were surprised by CXCR4-activated decidual cells in these mice, given the paucity of analysis of this receptor in these cells. However, beautiful work out this week in Nature shows a population of CXCR4+ decidual cells associated with blood vessels and pregnancy complications.
James Zwierzynski retweeted
Nature research paper: Developmental organization of sensory and sympathetic ganglia
go.nature.com/41GvsZm
