Bfx engr & pop gen product mgmt. O'author, PhD, 4x startup survivor. Pipelines, metadata, genomics, reproducible research. Gen X. https://xitter.cf/t.co/1l9OeLbyvr
Whitefish, MT
Joined October 2008
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Jeremy Leipzig retweeted
Even with sampling 1000 people in Shelby and finding 20 PhDs there would be surprising to me. I would definitely help an aspiring podcaster in the data journalism sphere if they want to unravel this mystery.
There are now 3 full-fledged Ensembl VEP Rust ports (fastVEP, vep-rs, vepyr) and 2 HGVS engines (mehari, vareffect)
Here is Claude's evaluation of them. Feel free to comment if you have the inside track.
docs.google.com/spreadsheets…
I remember all that hype around reconstructing dreams from fMRI using stable diffusion? No one believed it because it was obviously classifying noise to a limited corpus.
Now no one would believe it because they've seen AI generate movies from nothing.
My new Moose R package allows you to go from a pile of photos to a dichotomous key wizard. Features that arise from unsupervised visual concept discovery on patch embeddings are given fake placeholder names ("sniglets"). github.com/leipzig/moose
Why are there so many mcp scanners (glama, mcpdd, glimind, zevruna, talandor, on and on) door rattling if claude/gpt don't actually use them?
PM: let's wire all these household smoke detectors so they all go off at once even though even one is ear splittingly loud
Engr: but the one that triggers will sound different, or maybe flash?
PM: no
Engr: but there'll be some way to find the culprit in a false alarm?
PM: nah
at some point dbGaP loosened some of its elitist gatekeeping verbiage. it is better now (if a bit nonsensical sounding).
wayback 2025/08/09 vs today
i thought there were/are GABA antagonists you could give people to sober them up but they would still die of alcohol poisoning. this is much better, although life will get zany. fiercebiotech.com/biotech/go…
great talk about BioMCP by @imaurer, the background is especially helpful if you've missed the history leading up to the latest generation of LLMs, MCP servers, agents youtube.com/watch?v=lXoe-4TE…
How I feel reading about this
Andrew Tulloch, the star AI researcher who was offered a pay package worth more than $1 billion to join Meta last year, is leaving the company. on.wsj.com/46gJ9AB
Truly a 0->1 product dev experience at @plasmidsaurus
jobs.ashbyhq.com/plasmidsaur…
oh well the r/biotech is not reacting well to it:
reddit.com/r/biotech/s/MfD8P…
My repo github.com/leipzig/awesome-r… hit 400 stars today. This started as an offshoot of my dissertation and then got a life of its own. Will be interesting to see how this topic survives the robot apocalypse.
Works from my grandfather and his contemporaries at Dulwich Gallery in London theguardian.com/artanddesign…
