Principal Investigator @UAB_Biochem, protein/peptide scientist working on microbial pili and nanotube design | Views are my own | 😺⚡️👨🔬🍷☕️
Joined October 2020
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Thrilled to share our story of "lemon-shaped" virus SMV1 published at @CellCellPress
This is the first atomic structure of an archaeal lemon-shaped virus. Great collaboration with Virginija and @mkrupovic as always! (1/6)
authors.elsevier.com/c/1enwZ…
Fengbin Wang (Jerry) retweeted
Another wonderful collaboration with
@alanbrownhms lab. The Zhang lab together with @PolinaLishko lab (co-first author
@QingweiN) contribute the doublet microtubule structure from Crithidia fasciculata, a model organism that infects mosquitoes.
science.org/doi/10.1126/scie…
Fengbin Wang (Jerry) retweeted
Donor Strand Complementation and Calcium Ion Coordination Drive the Chaperone-free Polymerization of Archaeal Cannulae biorxiv.org/content/10.1101/…
Happy that the preprint is now published. Great collaboration with fantastic colleagues. @conticellolab @EmoryChem
Fengbin Wang (Jerry) retweeted
Our study on how the human MCM2-7 helicase is loaded onto replication origins 🧬 is now online @Nature! 🎉
Our findings reveal that unlike in yeast, human MCM loading does not require ORC6 and can occur through multiple pathways.
Read more here: rdcu.be/d1F6S
Fengbin Wang (Jerry) retweeted
🚨 We've updated the glycan structure database on @GlycoShape (glycoshape.org)! You can now search through and rebuild glycoproteins with 453 unique glycans 🥳
Glycans are now primarily listed by their GlyTouCan IDs @glytoucan @kiyokof 🎉
#glycotime
Fengbin Wang (Jerry) retweeted
The missing piece in the bacterial #ESCRT-III story.. #Vipp1 forms dynamic spiral filaments on membrane! Spirals are springs that drive 3D ring formation in the spiral centre! 😎😵💫 Wonderful collaboration with @Colom_D @RouxLab… 1/2
biorxiv.org/content/10.1101/…
Fengbin Wang (Jerry) retweeted
Researchers led by @PhilGuo1, @JunLiuLab, @Dr_Lori_Burrows report the structure of the Pseudomonas aeruginosa T4P suggesting the localization and role of its tip adhesin, PilY1.
nature.com/articles/s41467-0…
Fengbin Wang (Jerry) retweeted
@jerrynosnothing @mkrupovic @OhsuHuiWu used cryo-EM to determine the structures of three bacterial flagellar filaments, showing distinct outer domains.
nature.com/articles/s41467-0…
Fengbin Wang (Jerry) retweeted
Thank you Fengbin (Jerry) Wang @jerrynosnothing for inviting me to speak at @UAB_Biochem and meet Gino Cingolani @GinoCingolani2, Laura Volpicelli-Daley @lvolpic, Lindsay Rizzardi @LindsayRizzardi, Peter Prevelige, Matthew Renfrow, Shu Chen, Louise Chow, and Tom Broker.
Fengbin Wang (Jerry) retweeted
Our Manual Plunge Cooler and Precision Ethane Cryostat system for Cryo-EM are now available - Designed to make your cryo-EM sample vitrification workflow efficient and successful at a reduced cost - Learn more zurl.co/RoNE Video zurl.co/05n9 #cryoem
Fengbin Wang (Jerry) retweeted
Thrilled to announce AlphaFold 3 which can predict the structures and interactions of nearly all of life’s molecules with state-of-the-art accuracy including proteins, DNA and RNA. Biology is a complex dynamical system so modeling interactions is crucial blog.google/technology/ai/go…
Fengbin Wang (Jerry) retweeted
🔬👩🔬 Exciting news! I'll soon start my lab @VAInstitute to research molecular mechanisms in Neurodegenerative diseases. 🧠💡 Now recruiting postdocs to join our dynamic research team! Email me if you're interested! #Postdoc #CryoEM #Neuroscience #ResearchOpportunity
I guess our research future is bright... @VincentContice2
I didn't see this coming #3BodyProblem 🍷👽
Check out our new cryo-EM preprint on bacterial flagellar outer domain diversity! No clue who'll see this due to Twitter's new algorithm. Important points: most work was done by rotation students, and collaborating with the Wu lab is great. @OhsuHuiWu 🦠biorxiv.org/content/10.1101/…
wow our Geo nanowire structures were there! They were drawn in such an elegant way!! 🥳🤩🙌
February's Molecule of the Month:
Nanowires conduct electrons one at a time inside biological molecules.
pdb101.rcsb.org/motm/290
Fengbin Wang (Jerry) retweeted
Excited to finally share this final product!
Analysis of NIH K99/R00 awards and the career progression of awardees
elifesciences.org/articles/8…
There is bias in faculty hiring networks! bottom line.
Fengbin Wang (Jerry) retweeted
We have received a lot of requests for help with making streptavidin affinity grids. We are happy to finally share our protocol for robust in-house fabrication of streptavidin affinity grids. Stay tuned for the accompanying video that is coming soon!
app.jove.com/t/66197/strepta…
It's phenomenal. We use it every day to guess unknown pili sequences. For our recent 3.5 Å pilus structure in bioRxiv, the predicted sequence is 56% to the correct protein (using the default parameter). Our lab record is 85% correctness for a 2.4Å novel pilus structure. 🍷❄️
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Fengbin Wang (Jerry) retweeted
The #cryoEM research centers @UWBiochem are recruiting! We seek to hire an #administrative #assistant to join our team. We are looking for someone who has a passion for science, organization, communications, and outreach. Take a look! DM & RT! jobs.wisc.edu/jobs/administr…
Fengbin Wang (Jerry) retweeted
Excited to share the first paper from our lab is out as a preprint! @JoshuaHuffines established a dual-species culture model to investigate S. aureus-Corynebacterium interactions on nasal cells & how temperature influences bacterial persistence & cytotoxicity
Temperature Influences Commensal-Pathogen Dynamics in a Nasal Epithelial Cell Co-culture Model biorxiv.org/cgi/content/shor… #biorxiv_micrbio