馃КHER2 overexpression in up to ~90% of cases
鈽笍MRI: enhancement and thickening of the nipple-areolar complex, with retroareolar or segmental non-mass enhancement.
Image (pathology): Sharma A, et al. Cureus 2026;18:e110432 (CC BY 4.0)
Image (MRI): Mariano L, et al. Front Oncol 2025;14:1497506 (CC BY 4.0)
Ref: Choridah L, et al. J Med Case Rep 2020;14:119
Ref: Cantisani C, et al. Diagnostics 2025;15:1898
Image (pathology, US): Lin X, et al. Surg Case Rep 2020;6:143 (CC BY 4.0)
Ref: Lin X, et al. Surg Case Rep 2020;6:143
Chiang S, et al. Cancer Res 2016;76:7118-7129
猸昅edullary thyroid carcinoma
馃敩Nests of monotonous polygonal to plasmacytoid cells in a hyalinized stroma
馃КRET or RAS driver mutations, mutually exclusive in sporadic cases; germline RET in MEN2A/2B
猸旸uctal adenocarcinoma of the prostate
馃敩Papillary and cribriform glands lined by tall columnar pseudostratified epithelium
馃И尾-catenin+ (focal nuclear)
馃КAPC mutation with loss of heterozygosity (this case)