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California, USA
Joined December 2008
Libby Patterson retweeted
Scientists found a way to flush Alzheimer’s plaque out of the brain in minutes. Without any surgery and drugs. Your brain has a waste-clearance network called the glymphatic system. It flushes out toxic proteins and dead cells. But it only really activates during deep, slow-wave sleep. If you don't sleep, the trash piles up. Over time, that buildup leads to cognitive decline and Alzheimer's. Until today. Researchers just published a paper proving they can manually trigger this cleaning cycle. Without you ever going to sleep. They used 40.68 MHz ultrashort waves (USW) beamed non-invasively into the brain. Within 10 minutes, the brain's fluid flow rapidly accelerated. The waves artificially synchronized the neurons into a Delta state, the exact frequency of deep sleep. This forced the brain's water channels to open and start flushing out the system. They tested it on mice with traumatic brain injuries and Alzheimer's pathology. The brain swelling dropped. The toxic proteins were cleared out. Cognitive deficits actually improved. No surgery. No massive chemical interventions. Just a frequency.
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Libby Patterson retweeted
The way you talk to yourself can influence how your brain processes emotions, handles stress, and responds to difficult situations. Neuroscience research shows that inner speech, the silent conversations we have with ourselves, involves brain networks associated with language, attention, memory, and emotional regulation. When people repeatedly engage in negative self-talk, particularly rumination, they may reinforce patterns of thinking associated with anxiety and depression. Rumination involves repeatedly focusing on distressing thoughts without moving toward a solution. Brain imaging studies have linked self-referential thinking to activity in regions including the medial prefrontal cortex and parts of the default mode network, a system involved in thinking about ourselves and our experiences. Researchers have also found that changing how we speak to ourselves can influence emotional responses. For example, using your own name or speaking to yourself from a third-person perspective may help create psychological distance during stressful situations. Source: University of Michigan, Michigan State University, Journal of Personality and Social Psychology, and NIH.
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This is a bit of revisionist history. The UV catastrophe was really solved by the photoelectric effect. If Planck understood his own work he would have gotten Einstein's Nobel. In fact, Max Planck did not resolve the Ultraviolet Catastrophe by discovering the quantum nature of light; he executed a desperate mathematical curve-fitting hack that he spent the rest of his career trying to walk back. The Nobel Committee would like to bury this fact too because it shows you how biased centralized science is. The historical narrative stating that Planck's 1900 blackbody distribution law neatly solved the classical Rayleigh-Jeans divergence (the black curve running to infinity in the image) is a complete textbook fabrication. Planck did not believe that radiation itself was quantized; he assumed that quantization was merely a mathematical property restricted to the walls of the charcoal container (his localized resonators). He treated his own constant (h) as an abstract statistical convenience to prevent the math from blowing up into an infinite energy leak. It was Albert Einstein's 1905 derivation of the Photoelectric Effect that actually forced physics to accept that light travels as discrete wave-packets (photons). If Planck had truly grasped the sub-atomic physical implications of his own blackbody equations, he would have realized that light is an intrinsic manifestation of non-local field geometry, pre-empting Einstein's work entirely. In the context of my decentralized thesis, this historical blind spot mirrors the exact failure of modern biochemistry: just as classical 19th-century physicists tried to use smooth, continuous Rayleigh-Jeans equations to describe quantized light emission, modern medicine uses smooth, classical chemical pathways to analyze a highly quantized, spintronic mitochondrial semiconductor. You've been outed and have no clothes.
#OnThisDay in 1900, Max Planck presented his law of black body emission, Planck’s law. Planck's law (coloured curves) accurately describe black body radiation and resolved the ultraviolet catastrophe (black curve) a prediction of late 19th/early 20th century classical physics.
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Libby Patterson retweeted
Herbs for Stress Relief: Adaptogenic & Calming 🍀🌿 CBD Rose Reishi Mucuna Skullcap Mulungu Damiana Holy Basil Kava Kava Blue Lotus Milky Oats Schisandra Lemon Balm Passionflower Ashwagandha
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It was a matter of when, not if this Nobel would happen. Awesome to see it. It is worth noting that @KarlDeisseroth lab shared optogenetic tools far and wide from the very beginning, and thereby facilitated so much discovery. Fun fact: Karl was the first guest ever on the HLP.
BREAKING NEWS The 2026 #NobelPrize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
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My critique of this paper cuts straight through the fundamental hubris of modern theoretical physics. Mathematical equations can beautifully catalog the behavior of nature, but they are completely impotent at explaining the why behind its foundational constraints. Physicist Gunther Kletetschka’s 6D framework (3 dimensions of space, 3 dimensions of time) is an elegant mathematical exercise. It maps the three generations of fundamental particles (electron, muon, tau) onto the geometry of these extra temporal dimensions, attempting to heal the schism between general relativity and quantum mechanics. But it leaves me completely unsatisfied because it treats the universe as a sterile, abstract geometry, failing to provide any physical reason why this temporal schism exists to begin with, or why a macroscopic human observer is locked into experiencing time as a single, one-way road. My decentralized thesis explicitly provides the "why" that Kletetschka’s equations miss. The schism between the timeless, probabilistic quantum world and the irreversible, chronological macroscopic world is not an abstract mathematical mystery; it is a tangible, biophysical phase change mediated by the static dielectric constant of interfacial water inside your mitochondria.
🚨 WHAT IF TIME HAS THREE DIMENSIONS — AND WE ONLY EXPERIENCE ONE? We think of time as a single road: yesterday behind us, today beneath our feet, and tomorrow somewhere ahead. But what if that picture is only a small part of reality? Physicist Gunther Kletetschka of the University of Alaska Fairbanks has proposed a striking alternative: time itself may have three dimensions. His 2025 mathematical framework describes a universe with three dimensions of time alongside three dimensions of space, creating a six-dimensional structure that is very different from the familiar picture of spacetime. (DOI) In this idea, time would not simply flow along one direction. The extra temporal dimensions could provide additional ways for physical states to evolve while still preserving cause and effect. In simple terms, reality might have more “directions” in time than the one we experience from moment to moment. Kletetschka argues that the mathematical structure of the three time dimensions can produce the three generations of fundamental particles — including the electron, muon and tau, as well as the different families of quarks. His calculations also produce specific particle masses and make predictions for quantities such as neutrino masses and possible new high-energy resonances. (DOI) That makes the proposal more than a strange philosophical idea about time. If its predictions are correct, experiments could potentially look for signs of this hidden structure. The paper points to future collider experiments, gravitational-wave observations and cosmological surveys as possible ways to test parts of the framework. (DOI) There is an even bigger question hiding underneath it all. Modern physics has two extraordinarily successful descriptions of nature: quantum mechanics for the microscopic world and general relativity for gravity and the cosmos. Bringing them together has remained one of physics’ deepest challenges. Kletetschka’s framework is presented as a possible route toward connecting these worlds by making the geometry of time fundamental. But there is an important distinction: this is a theoretical proposal, not an established replacement for modern physics. Its predictions still need to survive experimental testing and scrutiny from the wider scientific community. If reality really has three dimensions of time, then the universe may be far stranger than the simple timeline we experience every second. Are we moving through time… or are we seeing only one direction of a much larger temporal universe? Source: Gunther Kletetschka, Three-Dimensional Time: A Mathematical Framework for Fundamental Physics, Reports in Advances of Physical Sciences, 2025. DOI: 10.1142/S2424942425500045. (DOI)
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Libby Patterson retweeted
The standard model of neurology assumes internal buzzing is anxiety, but axonal wiring shows those signals are physical errors you can now stop. This sensation is often a result of faulty axonal wiring—the long, thread-like fibers that transmit electrical impulses—firing without a stimulus. Think of a loose needle on a pressure gauge that vibrates constantly because the internal spring is damaged; the reading has nothing to do with the actual pressure. If you feel like your skeleton is humming at a frequency no one else can hear, you are likely dealing with a physical signal error. This is a mechanical failure where the brain sends a high-frequency motor command to a system that cannot resolve it. We can now address this through focused ultrasound, which uses concentrated beams to generate thermal energy at a specific bottleneck. This heat eliminates the neuronal clusters—small groups of brain cells—that are stuck in a feedback loop of over-excitation. By targeting the subthalamic nucleus, a lens-shaped structure responsible for regulating motor output, we can physically interrupt the pathway. It is the equivalent of snipping the wire to that vibrating gauge needle so the system can finally return to a neutral state of silence. Unlike chemical interventions, this process targets the dyskinesia—the involuntary, erratic muscle movements—at the source of transmission. It permanently alters the signal-carrying pathways rather than just masking the sensation with medication. This mechanical intervention provides an immediate reduction in symptoms because the physical hardware causing the hum is deactivated. Once the abnormal wiring is gone, the internal noise stops. The rest of the mechanism is worth a read. michaeljfox.org/news/focused…
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Libby Patterson retweeted
Stiff hips and a tight back are not “just age.” This flow opens the spine, hip flexors, hamstrings, chest, and ankles in 12 moves👇
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This neutrino idea has to link to the Beeswax Candle story too.  If time is created by the entropy of a Marcus Inversion event it makes sense to me that the candle flame oxidation rate has to be linked at some level to the neutrino story within. The Neutrino-Candle Paradox: Chronological Acceleration of the Material Matrix The absolute structural continuum of time creation is finalized by reconciling the Monk Candle Mystery, where traditional 24-hour beeswax candles are documented to fully oxidize within a compressed 18-hour window despite atomic clocks registering consistent mechanical intervals. Through a decentralized biophysical lens, this phenomenon is not a chemical anomaly, but the direct thermodynamic manifestation of Earth’s crust entering an acute Marcus Inversion phase. Because the planetary geodynamo has been in a systemic decline since the Carrington Event of 1859, the local space-time lattice is experiencing a significant drop in its native magnetic and kinetic "PSI" pressure. This field uncoupling collapses the local atmospheric water lattice down to a bulk phase (k=160 to k=78), removing the high-capacitance Galactic Line-Filter that historically stepped down cosmic radiation. Consequently, the un-attenuated influx of stellar electron antineutrinos alters the background rate of inverse beta decay equation, pictured above, within the atomic structures of carbon-hydrogen bonds. This sub-atomic quark-level flavor transition acts as an accelerated flow meter for entropy, directly overclocking the physical oxidation rate of the candle flame. The candle is not burning faster because of ambient heat; it is burning faster because the weakening geodynamo has un-clutched the material matrix from the core solar pacing grid. This perfectly mirrors the Biological SCRAM occurring inside the human pelvis and liver; when an individual lives suspended on the penthouse floor in a modern skyskraper under an artificial LED matrix, their inner mitochondrial membrane (IMM) experiences this identical sub-atomic time acceleration. The cell’s Terahertz pacing grid goes dark, 35% sperm or egg DNA fragmentation spikes  leads to infertility as the protamine tensegrity wires snap, and the body plan falls into an atavistic Precambrian safe mode to protect its core nuclear archive from total Landauer informational erasure.
The neutrino was not first confirmed by seeing the neutrino itself. It was confirmed by seeing the trace of this reaction. When an electron antineutrino meets a proton with enough energy, it can trigger inverse beta decay: ν̄ₑ + p → n + e⁺ At the deeper level, one up quark inside the proton changes into a down quark through the weak interaction. That is what turns the proton (uud) into a neutron (udd), while a positron is emitted. The threshold energy for this reaction is about 1.806 MeV, and it became one of the key processes in neutrino physics.
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Libby Patterson retweeted
Processed foods literally damage your brain, making you hungrier. Across multiple species (mice, macaque monkeys, and humans), there is evidence that processed food diets cause neuro-inflammation and astrogliosis in the satiety center within hypothalamus. This is not hyperbole. Mice (PMID 22381575): An evolutionarily inappropriate processed food diet causes microglial infiltration and astrogliosis of the arcuate nucleus. This inflammatory process prevents POMC neurons from “sensing” circulating leptin, leading to a deficit in the satiety response. Macaque monkeys (PMID 38892139): Equivalent findings to the mouse model. Processed food diets caused arcuate nucleus astrogliosis and deficits in leptin signaling. Humans (PMID 22201683): Obese humans show damage (astrogliosis) in the infundibular nucleus (homologous to the arcuate nucleus) on T2-weighted MRI. This directly leads to disordered hunger and satiety cues. This is what “food noise” looks like at an anatomical level. Those 200 calories of Oreos, Doritos, or any other garbage processed food are damaging the satiety center of your brain (the infundibular nucleus of the hypothalamus) and making you hungrier later. Come at me calorie bros... Interestingly, GLP-1s partially bypass this “brain damage” and help restore satiety. They have multiple side effects, but in some ways, they act as a partial antidote to the “food noise” caused by processed foods. The more elegant way to solve this problem is simply to eat unprocessed, single-ingredient foods (=food for humans) that do not damage the infundibular nucleus of the hypothalamus.
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Libby Patterson retweeted
New book alert. Dr. Andrew Huberman just released "Protocols" and it's taking the internet by a storm. Years of discussions about sleep, exercise, focus, stress and health... all into a single book. A playbook for putting the science into practice. Can't wait it read it.
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Libby Patterson retweeted
🚨 SCIENTISTS FOUND LIGHT INSIDE HUMAN CELLS Researchers discovered that tiny parts inside our cells may communicate using microscopic flashes of light called biophotons. These signals are invisible to the human eye, but scientists believe they could help cells coordinate, repair damage, and respond to stress. The discovery is changing how experts understand the human body — suggesting that deep inside us, cells may be “talking” through light itself. Source: Kučera, O., et al. *Biophotons and mitochondrial communication in living cells*. Photochemical & Photobiological Sciences.
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