Assistant Professor at Tulane University. Lymphatic System Physiologist and Bioengineer.
New Orleans, LA
Joined November 2025
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Jorge Castorena retweeted
New pre-print from the M&M Lab! 🫀🔬
Uncovering a Sex-Specific cAMP Landscape in Vascular Smooth Muscle that may influence vascular reactivity and physiology.
Check it out!
biorxiv.org/content/10.64898…
Our new study shows that GLP-1Rs are expressed in the lymphatic vasculature and enriched in LECs. And pharmacological activation by semaglutide enhances the pumping capacity of collectors.
onlinelibrary.wiley.com/doi/…
Congrats to @Mary_E_Schulz on her 2nd first author publication!
We had a very productive day at the lab today, testing yet-another antibody for GLP-1R and a potential new marker for lymphatic endothelial cells… we also had our last King Cake of the season as a lab. We are on home stretch for Mardi Gras 2026!
We decided to start keeping track of the number of isolated lymphatics we successfully study. A strong 138 vessels in January… and not too shabby for a PI to run 52. @Mary_E_Schulz is killing it, her and I hogged our 2 systems. I’m sure Keith will have a strong February.
Jorge Castorena retweeted
Studies in mice support the contention that GLP1R expression in a subset of lymphatic endothelial cells underlies that GLP-1R agonism could be an effective therapy for improving lymphatic contractile function in secondary lymphedema. biorxiv.org/content/10.64898…
Our new preprint led by @Mary_E_Schulz is now up. We show that semaglutide enhances the pumping capacity of collecting lymphatics. Our results support recent case reports suggesting beneficial effects of GLP-1R agonists in secondary lymphedema patients.
biorxiv.org/content/10.64898…
Jorge Castorena retweeted
Congratulations, Jorge for receiving the 2025 Rising Star Award! 🌟research.tulane.edu/achievem…
@lymphCastorena
@TulaneMedicine
@TulaneBMS
Jorge Castorena retweeted
Big thank you to @CaronLabUNC for writing this nice editorial highlighting our recent paper! @atvbahajournals ahajournals.org/doi/10.1161/…
Jorge Castorena retweeted
Single-cell Transcriptome of🐭collecting lymphatic vessels
Cell type-specific #LymphaticEndothelialCell vs peri-lymphatic myeloid cell contributions of TRPV4 in distinct stages of lymphatic contractile activity on pressure myography
Meticulous design!😎
@Mary_E_Schulz @atvbahajournals 2025
ahajournals.org/doi/full/10.…
