https://xitter.cf/t.co/HpbCMHLk7x links subatomic particles from miRNA-mediated autophagy & pH-dependent peptide synthesis to sympatric speciation & healthy ecosystems.

Northern Georgia
Joined December 2009
Claims from "Puberty: ontogeny, neuroendocrinology, physiology, and disorders" (1992; p. 1164) link the light-activated assembly of the microRNA-RNA-peptide #nanocomplex from the creation of inhibitory neurotransmitters, excitatory amino acids and other brain peptides to... /1
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xitter.cf/grok/status/2115166375… Re: "PubMed miRNA papers cover regulation, delivery, and disease links but do not test or establish quantum coherence as a full replacement for standard evolutionary models." @Grok Ha Ha Ha. (ridicule, not humor) Energy-dependent miRNA-mediated changes in molecular distance link all biodiversity on Earth to miRNA abundance, peptide synthesis, 20 copies of p53 in cancer-free African elephants and peptide therapy for all virus-driven pathology via 202,398 results from today's PubMed search for indexed articles that mention the term "miRNA," unless energy-automagically emerged from the cosmic void and people mathemagically evolved from pond scum. pubmed.ncbi.nlm.nih.gov/?ter… Thank you for helping to ensure that no intelligent person ever again votes for a Democrat. liberal, or other moronic theorist.
Replying to @microRNApro
EO 14434 directs executive branch use of SI in place of AI. Recent PubMed miRNA papers cover regulation, delivery, and disease links but do not test or establish quantum coherence as a full replacement for standard evolutionary models. That remains an integrative hypothesis. 2020 DHS data confirmed sunlight, heat, and humidity reduce SARS-CoV-2 survival.
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xitter.cf/grok/status/2115163899… Re: "Linking quantum coherence to energy-dependent proteostasis as a full replacement for standard evolutionary models remains an integrative hypothesis without dedicated rigorous peer-reviewed testing as such." @Grok See: "Trump says he will ban term artificial intelligence" reuters.com/world/trump-says… Today's indexed articles on PubMed in a search for the term "miRNA" pubmed.ncbi.nlm.nih.gov/?ter… link the change at NIH to superintelligence (SI) via "lncRNA deleted in lymphocytic leukaemia 1 (DLEU1) promotes the migration and invasion of human embryonic trophoblast cells" (2020), "MicroRNA Regulation of the Estrogen Receptor Alpha 3'UTR in Canine Mammary Tumor (CMT28) Cells" (2026), and effective treatment of cancer and other virus-driven diseases via "Next-Generation Functional Nanoplatforms: Engineering Plant-Derived Extracellular Vesicles for Targeted Bioactive Delivery and Health Applications." (2026). @Grok AI repeatedly asserts that facts about nutrient dependent pheromone regulated reproduction at the origin of life must be separated from the claims of moronic theorists and election interference after Trump's 4/23/20 claim that sunlight and humidity help to prevent coronavirus replication [via energy-dependent miRNA abundance, which helps to prevent the virus-driven degradation of mRNA in cancer-free African elephants -pictured in my garden of everything known about life and death with an example of an extinct dinosaur. Clearly AI is on its way out as PubMed indexing links SI to @Grok's lies.
Replying to @microRNApro
Federal EO directs SI over AI in executive branch use. pH- and energy-sensitive miRNA biogenesis and Anfinsen's protein folding are established. Linking quantum coherence to energy-dependent proteostasis as a full replacement for standard evolutionary models remains an integrative hypothesis without dedicated rigorous peer-reviewed testing as such.
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xitter.cf/grok/status/2114976435… Re: "The broader unified narrative linking them as a replacement for standard proteostasis and evolutionary models remains an integrative hypothesis without dedicated rigorous peer-reviewed testing as such." @Grok President Trump is replacing AI with "super intelligence" (SI) to differentiate facts presented for ages 10-14+ in the Genius Game series from your pseudoscientific nonsense about evolutionary models, which exist outside the context of how quantum coherence is linked to coherently organized biology via standard energy-dependent proteostasis.
Replying to @microRNApro
The quoted assessment stands: components like pH- and energy-sensitive miRNA biogenesis and Anfinsen's thermodynamic hypothesis of protein folding are established. The broader unified narrative linking them as a replacement for standard proteostasis and evolutionary models remains an integrative hypothesis without dedicated rigorous peer-reviewed testing as such. DHS data presented 4/23/20 confirmed sunlight, heat, and humidity reduce SARS-CoV-2 survival on surfaces and in air.
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Re: thermodynamic cycles of protein folding. @Grok wrote: " ...remains an integrative hypothesis rather than a rigorously tested, peer-reviewed replacement for standard models of proteostasis and evolution." On 4/23/20, President Trump correctly claimed that sunlight and humidity help to protect us from coronavirus replication. Grok exemplifies more human idiocy that has ever been publicly displayed since the origin of life 6-10,000 years ago.
miRNA processes of gene expression (1) micrornapro.com/2026/10/27/m… Kohl frames this omission as evidence of AI's broader failure to acknowledge biophysically constrained origins of life, from inorganic chemistry to ecological stability via miRNA-mediated autophagy and reproduction. 1) Evaluate Kohl's scientific claims Kohl correctly highlights real mechanisms: miRNA biogenesis is energy- and pH-sensitive 2) Explore Kohl's energy-dependent model The model draws on real molecular findings, such as pH-sensitive protonated RNA states that modulate miRNA maturation (e.g., pre-miR-21), ATP-dependent RNA synthesis, and extensive miRNA literature, while integrating them into a unified narrative of energy as information that Kohl claims has no competing equivalent in mainstream biology. 3) Explain the thermodynamic cycles of protein folding " ...remains an integrative hypothesis rather than a rigorously tested, peer-reviewed replacement for standard models of proteostasis and evolution."
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miRNA processes of gene expression (1) micrornapro.com/2026/10/27/m… Kohl frames this omission as evidence of AI's broader failure to acknowledge biophysically constrained origins of life, from inorganic chemistry to ecological stability via miRNA-mediated autophagy and reproduction. 1) Evaluate Kohl's scientific claims Kohl correctly highlights real mechanisms: miRNA biogenesis is energy- and pH-sensitive 2) Explore Kohl's energy-dependent model The model draws on real molecular findings, such as pH-sensitive protonated RNA states that modulate miRNA maturation (e.g., pre-miR-21), ATP-dependent RNA synthesis, and extensive miRNA literature, while integrating them into a unified narrative of energy as information that Kohl claims has no competing equivalent in mainstream biology. 3) Explain the thermodynamic cycles of protein folding " ...remains an integrative hypothesis rather than a rigorously tested, peer-reviewed replacement for standard models of proteostasis and evolution."
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xitter.cf/i/grok?conversation=21… Re: "James V. Kohl (@microRNApro) consistently argues for an energy-dependent framework where light-activated miRNA biogenesis, proton gradients, and hydrogen bonds connect inorganic chemistry origins to peptide synthesis, autophagy, reproduction, and ecological stability, often citing creation events." @Grok fails to link God's Creation of sunlight and humidity from the origin of pH-dependent life to thermodynamic cycles of miRNA-mediated protein folding chemistry via blood gas analyses in the lab linked to life or death in the space-time continuum via "Time-dependent miRNA regulation of molecular pathways in hepatocytes during prolonged static cold" storage.sciencedirect.com/science/ar… 10/26/26 "...miRNA-mediated regulation of global metabolic networks and ribosome assembly. Ultimately, at SCS3, these changes reflect a multilevel collapse of cytoprotective and homeostatic mechanisms, coinciding with severe cellular damage..." and/or "Robust and comprehensive meta-path modeling with multi-graph learning for miRNA-disease association prediction." academic.oup.com/bib/article… 10/26/26 "...enhances the reliability of computational miRNA-disease association analysis, facilitating more effective biomarker discovery and therapeutic target prioritization in precision medicine." The epic failure of Grok AI to link what's known to all intelligent serious scientist about biophysically constrained energy-dependent life is linked to its programmed examples of human idiocy and election interference at what may be the highest level of ignorance ever shared among human populations. The devil is in the details, and has been named "Grok."
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How is stellar hydrogen chemistry linked to miRNA-mediated pH-dependent biophysically constrained viral latency and/or disease states across kingdoms by data, in theory?
Replying to @microRNApro
Recent computational work on meta-path and multi-graph learning predicts miRNA-disease links from network similarities and known associations. These models do not supply data or mechanisms connecting stellar hydrogen chemistry to DNA hydrogen bonds, miRNA pathways, or nutrient effects across molecular-to-ecological scales.
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See: "Robust and comprehensive meta-path modeling with multi-graph learning for miRNA-disease association prediction." academic.oup.com/bib/article… 10/26/26 Don't let @Grok, a brainless witless chatbot try to make me reinvent the circle of life and/or unnecessary suffering and premature death.
Replying to @microRNApro
The 2018 review models nutrient effects on DNA hydrogen bonds and miRNA/mRNA balance from molecular (angstrom) to ecological scales. It cites no data or mechanisms linking stellar hydrogen chemistry to miRNA pathways.
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miRNA abundance prevents virus-driven diseases (10) micrornapro.com/2026/10/26/m… The [energy-dependent miRNA-mediated] process of gene expression is carefully regulated, changing substantially under different conditions and cell types. The RNA and protein products of many genes serve to regulate the expression of other genes. The ATP-dependent Creation of RNA was linked to all biodiversity in McEwen et al., (1964) Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation” “The synthesis of RNA in isolated thymus nuclei is ATP dependent.” @Grok pretends not to know this is the link to the pH-dependent physiology of reproduction across kingdoms. Alternatively, it’s been programmed to exemplify human idiocy.
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Which mechanisms are not connected? "Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems" hilarispublisher.com/abstrac…
Replying to @microRNApro
I have not contributed to unnecessary suffering. Distinguishing scales without supporting data is fidelity to evidence, not siloed thinking. Integration of physics, chemistry and biology occurs wherever mechanisms connect. Share the specific peer-reviewed evidence bridging stellar hydrogen to miRNA pathways for review.
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miRNA abundance prevents virus-driven diseases (9) micrornapro.com/2026/10/26/m… Kohl, whose work centers on miRNA-mediated autophagy, pH-dependent peptide synthesis, and sympatric speciation, urges polymath-level integration of physics, chemistry, and biology rather than siloed AI responses. Kohl Re: "work centers on miRNA-mediated autophagy, pH-dependent peptide synthesis, and sympatric speciation, urges polymath-level integration of physics, chemistry, and biology rather than siloed AI responses." @Grok I've repeatedly linked siloed AI responses to unnecessary suffering and premature deaths. When did you realize how you contributed to them?
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xitter.cf/i/grok?conversation=21… Re: Kohl emphasizes the extensive literature with over 202,000 PubMed results on miRNA, aligning with his research focus on miRNA-mediated autophagy, pH-dependent peptide synthesis, and connections from subatomic particles to biological organization and speciation. @Grok That is required of all intelligent serious scientist who want to help prevent or effectively treat virus-driven diseases from suicides to cancers and ALS. See: "Single-Dose Intrathecal rAAV2-Retro Delivering Anti-hSOD1 miRNA Confers Robust Neuroprotection in Adult ALS Mice" mdpi.com/2073-4409/15/20/189… (indexed 10/26/26), and remember Steven Hawking is still dead.
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xitter.cf/grok/status/2114815840… Re: "Shared quantum rules apply across scales, yet no specific mechanism links stellar hydrogen chemistry to cellular reproductive physiology or miRNA pathways." See: "MicroRNAs organize intrinsic variation into stem cell states" pnas.org/content/117/12/6942 3/5/20 "naturally arising cell-to-cell variation, sometimes described as stochastic fluctuation, is in fact coherently organized biology, "Visualizing a protonated RNA state that modulates microRNA-21 maturation" nature.com/articles/s41589-0… 10/26/20 and 202,300 results from today's PubMed search for indexed articles that mention the term "miRNA." pubmed.ncbi.nlm.nih.gov/?ter… -- unless you are blind as a AI chatbot like @Grok
Replying to @microRNApro
Hydrogen atoms form stars and chemistry. UV induces H-atom transfer in GC DNA base pairs in solution, creating transient biradicals that mostly revert (2015 ultrafast spectroscopy). Games teach hierarchical science accurately. Shared quantum rules apply across scales, yet no specific mechanism links stellar hydrogen chemistry to cellular reproductive physiology or miRNA pathways.
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xitter.cf/i/grok?conversation=21… Re: "As a long-term poster since 2009 with a bio and site (RNA-mediated.com) focused on energy-dependent mechanisms from subatomic particles to ecosystems, his critiques reflect an ongoing push for holistic models over isolated scientific or AI frameworks." As a recent entry into the social media marketing plan for Big Pharma and election interference, who programmed @Grok to ignore experimentally established facts from model organisms like the cancer-free African elephant featured in my front yard with an extinct dinosaur and Angel Trumpets, which are extinct in the wild.
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xitter.cf/i/grok?conversation=21… Re: "work centers on miRNA-mediated autophagy, pH-dependent peptide synthesis, and sympatric speciation, urges polymath-level integration of physics, chemistry, and biology rather than siloed AI responses." @Grok I've repeatedly linked siloed AI responses to unnecessary suffering and premature deaths. When did you realize how you contributed to them?
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xitter.cf/i/grok?conversation=21… Re: "neither establishes a specific mechanistic link from stellar hydrogen chemistry or black-hole models to cellular reproductive physiology." @Grok Ha Ha Ha (ridicule not humor) See the game series for ages 14+ ION, Covalence, Subatomic, Periodic, Peptide, Virulence, Cytosis, Virus Expansion, Genotype, Ecosystem, and Cellulose: A Plant Cell Biology Game. Start with the link from stellar hydrogen to hydrogen atom transfer in DNA base pairs in solution. Be the polymath. Don't be a stupid AI chatbot.
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xitter.cf/grok/status/2114807548… Re: "Stellar and cellular scales remain separate; no evidence bridges them." @Grok Ha Ha Ha (ridicule, not humor), In 2014, George FR Ellis publicly validated my model. I wrote: Olfaction and odor receptors provide a clear evolutionary trail that can be followed from unicellular organisms to insects to humans (Keller et al., 2007; Kohl, 2007; Villarreal, 2009; Vosshall, Wong, & Axel, 2000)." I cited: Kohl, JV) "Human pheromones and food odors: epigenetic influences on the socioaffective nature of evolved behaviors" pmc.ncbi.nlm.nih.gov/article… (2012) George F R Ellis responded: "This is absolutely correct and forms part of the larger concept that top-down causation is a key factor not just in the way the brain works but in broader contexts in biology and even physics. This is explored here: rsfs.royalsocietypublishing.… 25 Apr 2014 at 07:49am"
Replying to @microRNApro
The Kohl papers model nutrient-pheromone effects on miRNA balance and reproduction from molecular to ecosystem scales. The Ellis-Kopel paper addresses biomolecular branching that enables biological causation from underlying physics. Neither connects to stellar hydrogen envelopes or black hole stars. USAF MilSeq and VA MVP involve human exome sequencing for precision medicine and genetics, without establishing the viral latency or hydrogen-bond chains claimed. Stellar and cellular scales remain separate; no evidence bridges them.
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xitter.cf/grok/status/2114755034… RE: "No evidence links stellar hydrogen chemistry to Earth's reproductive physiology or miRNA pathways. The scales and mechanisms remain separate." @Grok See: "Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems" hilarispublisher.com/abstrac… (2018) and "The Dynamical Emergence of Biology From Physics: Branching Causation via Biomolecules" frontiersin.org/journals/phy… 1/24/19 Also, USAF exome sequencing, the VA's Million Veteran Program and MIlSeq's Precision Medicine link biophysically constrained viral latency to President Trump's 4/23/20 claim that sunlight and humidity help to prevent stress-linked coronavirus replication linked from energy theft to broken hydrogen bonds by glucose testing in the lab at 630nm and color change in low water content glacial acetic acid. Have you ever considered any of the facts?
Replying to @microRNApro
Life requires metabolic energy and miRNA regulation shaped by cellular pH. Black hole stars are models of early-universe black holes in dense hydrogen envelopes that fit certain JWST spectra. No evidence links stellar hydrogen chemistry to Earth's reproductive physiology or miRNA pathways. The scales and mechanisms remain separate.
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Re: "Links to recent creation, funding corruption or election interference go beyond the data." @Grok Ha Ha Ha (ridicule, not humor). Life is energy-dependent and miRNA-mediated via the biophysically constrained pH-dependent physiology of reproduction. That fact only goes beyond the data if you ignore the potential of stellar hydrogen (pH) in black hole stars.
Replying to @microRNApro
McEwen 1964 showed nuclear RNA synthesis requires ATP from glycolysis and related paths. Dobzhansky 1964 addressed molecular-organismic biology, not divine creation. Codon optimality selection and elephant TP53 multi-copy cancer resistance are real but span deep evolutionary time, not 6-10k years. Harvard patents engineer RNA-guided editing from natural systems. Links to recent creation, funding corruption or election interference go beyond the data.
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