@mostly_microbes

St. Louis to Boston! Postdoc at Tufts👨‍🔬🍷🏳️‍🌈

Joined March 2014
  • Tweets172
  • Following417
  • Followers186
29Media
Protection against C. diff by avirulent strain: @sciissue_077 show avirulent C. difficile isolate ST1-75 outcompetes virulent C. difficile to protect mice from colitis, likely by depleting amino acids. ST1-75 has biotherapeutic potential for recurrent CDI cell.com/cell-host-microbe/a…
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We are hiring! If you (or someone you know) is looking for a PostDoc position focused on Clostridial genetics with broad applications, please check out our position: tinyurl.com/r65jwwcz Come and join us in the vibrant science town of Boston!
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Pride in STEM Day Virtual Symposium is TOMORROW, November 18!🏳️‍🌈 🔬 🏳️‍🌈 Join us to hear from our community members and explore the science that unites us. The event will conclude with an informal Coffee Hour to connect with our global network Register here: forms.gle/kYKJKn1CaywBzJgV9
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It has been 10 years since I started doing Western blots in the lab. Wow, what a rollercoaster! Based on my successes and failures, here are some tips for perfect Western blots. A thread (1/5)…
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Greg Harrison retweeted
Qiwen Dong@sciissue_0778 May 2024
Following up our Cell Reports paper, an avirulent C. difficle clinical isolate out-competes virulent strains in mice via quickly depleting multiple amino acids, and protects mice from developing colitis!
bioRxiv@biorxivpreprint8 May 2024
Protection against Clostridioides difficile disease by a naturally avirulent C. difficile strain biorxiv.org/cgi/content/shor… #bioRxiv
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New preprint! biorxiv.org/content/10.1101/… Genome engineering in Clostridia is arduous. With help from @jgi we screened a large library of recombinases to enable oligo recombineering in E. limosum. The library is based on widely used Clostridial parts and available for others to use

Development of a recombineering system for the acetogen Eubacterium limosum with Cas9 countersele...

Eubacterium limosum is a Clostridial acetogen that efficiently utilizes a wide range of single-carbon substrates and contributes to metabolism of health-associated compounds in the human gut microb...

biorxiv.org
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"But I have this fear that some #science students avoid branching out, not because they don’t want to, but because they believe they’re not supposed to." #AcademicChatter brnw.ch/21wGWF6

Scientists, it’s OK to be well-rounded

Exploring other interests doesn’t make you less of a scientist, our Experimental Error columnist writes

science.org
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I am still looking for postdocs to join my lab. I have several NIH-funded positions to work either on Acinetobacter pathogenesis or OMV biogenesis in Bacteroides. Please RT.
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Greg Harrison retweeted
Shen Lab@ShenLabTufts21 Dec 2023
Happy holidays! Super fun making this fully edible gingerbread waterbath for our dept holiday party with this amazing group of people! ⁦⁦@sciissue_077⁩ ⁦@JacobBouchier⁩ ⁦⁦@mostly_microbes⁩
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Really happy to have this officially published! Thanks to @ShenLabTufts, @SGribaldo, and Najwa for their amazing support! Give it a read if you’re interested in bacterial cell division, spore formation, and the evolution of PG synthases that drive them: nature.com/articles/s41467-0…

Diversification of division mechanisms in endospore-forming bacteria revealed by analyses of...

Nature Communications - The enzymes FtsW and FtsI are thought to be essential for the synthesis of septal peptidoglycan (PG) during bacterial cell division. Here, Shrestha et al. show that the...

nature.com
Shailab Shrestha@shailabshrestha8 Aug 2023
So excited to finally share this work!! We found an unexpected repurposing of canonical division enzymes during the evolution of endospore formation and some surprisingly unique aspects of cell division in C. difficile. Check out our preprint: rb.gy/j5uvc
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From carbon dioxide to starch—no plants required. In Science, researchers developed a cell-free method of synthesizing starch from CO2 and hydrogen using a combination of chemical catalysts and a carefully selected set of enzymes. scim.ag/4J8 #ScienceMagArchives
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Erin Green@erin_r_green26 Oct 2023
My lab at @UChicago_Micro is hiring! We are looking for a research tech to work with us studying mechanisms of bacterial stress response and pathogenesis. Would be a great opportunity for recent college grads looking for research experience. Please spread the word! Links below
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Greg Harrison retweeted
The Pi Lab@hualiang20185 Sep 2023
We're hiring a lab manager, a postdoctoral research, and a postgraduate. See attached below for details. Please RT.
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The LeRoux lab (leroux-lab.org) is looking for a postdoc! Interested in discovering and understanding mechanisms of phage/bacterial interactions in the opportunistic pathogen Pseudomonas aeruginosa? Apply here: wustl.wd1.myworkdayjobs.com/…. Please retweet!

LeRoux Lab

LeRoux Lab @ WashU

leroux-lab.org
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In my three months of industry experience here is what I've learned so far in meme form
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Greg Harrison retweeted
Sigma-Aldrich@SigmaAldrich1 Apr 2022
🤔 Can you synthesize this newly discovered molecule? Rashnovinol A is a natural product isolated from Twigis gigantus, a stick-like insect from Europe. While ample in the insects, no successful syntheses exists due to its tricky structure complexities & rare functional groups.
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My lab is officially in business! And the first piece of equipment is the most critical one. Thanks to @StallingsLab for funding it! – at Beijing, People's Republic of China
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profloumoore@loumoore1215 Apr 2021
You can't reform this. Not in 1915. Not in 2021. Not in Atlanta. Not in Chicago.
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Our lab at @TheCrick is looking for a Laboratory Research Scientist interested in bacterial genetics, #TB, #AMR, chemical biology, and/or high throughput screening. Come work at a vibrant, collaborative research institute and help us #stopsuperbugs! crick.wd3.myworkdayjobs.com/…
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I’m safe on Mars. Perseverance will get you anywhere. #CountdownToMars
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