@mscott0106

Leverhulme ECF @biouea. Formerly postdoc @UGI_at_UCL with @RichardMott7 and PhD @UBCBiodiversity with @sarperotto.

 Norwich, UK
Joined January 2011
  • Tweets226
  • Following1K
  • Followers547
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In @GenomeBiology (genomebiology.biomedcentral.…), a big #openaccess breeding, genotyping, and phenotyping resource to dissect trait genetic architecture across 70 years of wheat breeding. @UGI_at_UCL @niabgroup 1/8

Limited haplotype diversity underlies polygenic trait architecture across 70 years of wheat breeding

Genome Biology - Selection has dramatically shaped genetic and phenotypic variation in bread wheat. We can assess the genomic basis of historical phenotypic changes, and the potential for future...

link.springer.com
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Leveraging one of the world’s oldest biological experiments, which began in 1929, researchers in Science have uncovered how a major crop, barley, was shaped by both agricultural pressures and its changing natural environment. Learn more: scim.ag/7IG
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Inversions are likely to contain locally adaptive alleles with relatively large effects. New article in @GeneticsGSA lead by Carl Mackintosh with @MaxReuterEvo @andrew_pom doi.org/10.1093/genetics/iya… @uclbiosciences

Locally adaptive inversions in structured populations

Abstract. Inversions have been proposed to facilitate local adaptation, by linking together locally coadapted alleles at different loci. Prior work address

academic.oup.com
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I am very happy to announce the recent publication of a beautiful theory paper with @mscott0106 and Karl Mackintosh (not on X) on the interactions between mating system evolution and haploid gametic selection in @PLOSGenetics doi.org/10.1371/journal.pgen…
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ICYMI 🌿🧬Multi-trait ensemble genomic prediction and simulations of recurrent selection for long-term genetic gains in #wheat @nickfradgley @niabgroup @plantsci @AlisonRBentley @breederphil @IanJMackay @mscott0106 @RichardMott7 @james_f_cockram bit.ly/3TMWQ3n

Multi-trait ensemble genomic prediction and simulations of recurrent selection highlight importance...

Abstract. Cereal crop breeders have achieved considerable genetic gain in genetically complex traits, such as grain yield, while maintaining genetic divers

academic.oup.com
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Strong Purifying Selection in Haploid Tissue–Specific Genes of Scots Pine Supports the Masking Theory buff.ly/3P65KXD From @PyhaTanja #science #evolution #biology #genome
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Michael Scott retweeted
Mick Crawley@crawley_mick30 Jul 2023
There’s an interesting bit of insect ecology on display at the moment. I’m sure you remember the massive acorn crop last year (autumn 2022, below). Because Quercus robur is alternate-bearing (big crops are always followed by little crops) we predicted a very low crop this year
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🚨New Preprint Alert 🚨  @yanivbrandvain  & I ask when and how recessive lethality can adaptively evolve on a chromosomes that selfishly distorter meiotic segregation? More in the 🧵 - 1/14 biorxiv.org/content/10.1101/…

Together Inbreeding and Reproductive Compensation Favor Lethal t-Haplotypes

Male mice who are heterozygous for distorting and non-distorting alleles at the t -haplotype transmit the driving t -haplotype around 90% of the time – a drastic departure from Mendelian expectatio...

biorxiv.org
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Michael Scott retweeted
BotigueLab@BotigueL12 Jul 2023
Looking for a Postdoc in crop genome evolution? Contact me if interested! We’re offering projects related with flax domestication, evolution of free-threshing wheat and building and analysing several crop pangenomes! #ancientDNA #CWR #PopGen
CRAG@cragenomica5 Jul 2023
📢 New #OpenCall for 8 #Postdoc fellowships on the @MSCActions #COFUND project #AGenT! 🗓️ Open until 27 August 2023 🔗 cofund-agent.eu/ #PlantSciJobs #OpenPosition #ScienceJobs #OpenCall
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Michael Scott retweeted
Andy Gardner@drandygardner3 Aug 2022
New paper: "Density-dependent dispersal promotes female-biased sex allocation in viscous populations" (#OpenAccess), with Chedhawat Chokechaipaisarn (not on Twitter) doi.org/10.1098/rsbl.2022.02… #Dispersal #KinSelection #SexRatio @SchoolofBiology @StLeonards_PGs @RSocPublishing #OA
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NEW! 🌿🧬Multi-trait ensemble genomic prediction and simulations of recurrent selection for long-term genetic gains in #wheat @nickfradgley @niabgroup @plantsci @AlisonRBentley @breederphil @IanJMackay @mscott0106 @RichardMott7 @james_f_cockram bit.ly/42rjoKO
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Carl noticed that alleles with large effects may be particularly important for inversion evolution.
Andrew Pomiankowski@andrew_pom7 Dec 2022
Very informative paper on how inversions facilitate local adaptation in the face of migration of maladapted haplotypes @carl_mackintosh @MaxReuterEvo @mscott0106 biorxiv.org/content/10.1101/…

The establishment of locally adaptive inversions in structured populations

Inversions have been proposed to facilitate local adaptation, by linking together locally coadapted alleles at different loci. Classic prior work addressing this question theoretically has considered...

biorxiv.org
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Michael Scott retweeted
BotigueLab@BotigueL29 Nov 2022
📢 Latest paper from the Botigué Lab @CRAGENOMICA is out! rdcu.be/c0sOq New evidence on genetic structure, evolution and early dispersal of Triticum turgidum ssp. dicoccum (emmer wheat). Analyses done by Alice Iob over the past few years. 🧬 #wheat #Neolithic 🧵
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Michael Scott retweeted
Nick Fradgley@nickfradgley9 Nov 2022
New pre-print! "Multi-trait ensemble genomic prediction and simulations of recurrent selection highlight importance of complex trait genetic architecture in long-term genetic gains in wheat" biorxiv.org/content/10.1101/… @niabscience

Multi-trait ensemble genomic prediction and simulations of recurrent selection highlight importance...

Cereal crop breeders have achieved considerable genetic gain in genetically complex traits, such as grain yield, while maintaining genetic diversity. However, focus on selection for yield has...

biorxiv.org
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Michael Scott retweeted
Rafal Gutaker@rgutaker6 Sep 2022
🌾🦠Excited to advertise postdoc position, based at Kew, London. I am looking for someone with comparative genomics and/or metagenomics background to join my team and study the pre-industrial rice and its microbial ecosystem. 3-years post. Please retweet! careers.kew.org/vacancy/post…
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Looking for a 2-years postdoc researcher and/or a 3-years PhD student with a background in population genetics and statistical genomics. Please RT and DM if you are interested in analyzing MANY ancient horse genomes to assess the impact of horses in human history.
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🎉Pleased to share my first paper with @SimoneImmler @biouea entitled "The potential role of the mobile and non-coding genomes in adaptive response" covering #miRNAs #piRNAs and #TEs 🚨Full-text available @TrendsGenetics open-access here: authors.elsevier.com/sd/arti…
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Michael Scott retweeted
Richard Mott@RichardMott722 Jul 2022
New @TheorApplGenet paper on historical selection in winter wheat with @cjyang90, @IanJMackay, @Funmielad, @SRUCPrincipal. Historical allele frequency changes increased yield, but reduced flowering time, lodging, plant height and grain protein content. rdcu.be/cSbei
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"Arabidopsis thaliana flower with pollen tubes growing through the pistil. The flower tissues were chemically cleared to become transparent, while the pollen tubes were stained with aniline blue (yellow fluorescence) in order to be seen."
Evident Life Science@Evident_LS27 Apr 2022
Congrats to Jan Martinek from the Czech Republic for being selected as this year's global #ImageoftheYear winner! For more information about this image and our other winners, visit - fal.cn/3o89q
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Michael Scott retweeted
Richard Mott@RichardMott74 Mar 2022
We have a postdoc available at @UGI_at_UCL in Genetic Privacy and Cryptography, funded by @BBSRC. Apply at tinyurl.com/nhk26bt9 by Mar 28. See bit.ly/3hlwWBY for the science.
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