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NCURE

@ncure_lab
Joined July 2025
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🇱🇻 nCureLab in Riga! Our PhD student Paulina Dudzik visited NIRI through COST Action SIGMA-1 EUROPE, gaining experience in in vivo studies of social behavior. Many thanks to Dr. Līga Zvejniece and Dr. Baiba Švalbe for their warm welcome!
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🧠 New research from nCure Lab! NLX-101, a biased 5-HT1A agonist, improved working memory and cognitive flexibility under NMDA receptor hypofunction, alongside enhanced prefrontal ERK2 phosphorylation. 🔗sciencedirect.com/science/ar…
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🏆 Congratulations to Pola Mazur from SSG NeuroPharm on winning 1st place in the scientific competition at the X Jubilee Congress of the Polish Pharmaceutical Students’ Association! Pola presented findings from a student research grant. 👏
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New paper 🧠 HBK-10 engages sigma-1 receptors, protects neuronal cells from amyloid-beta injury, and improves selected memory domains under NMDA receptor hypofunction in mice. Read: doi.org/10.1016/j.bcp.2026.1… #Neuropharmacology #Sigma1Receptor #nCureLab
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🧠🇪🇸 nCure Lab at #FENS2026 in Barcelona! Our PhD student Paulina Dudzik presented results from her research on novel multimodal compounds with potential to address psychosis-related symptoms and cognitive impairment. 🔬✨ Great to see nCure Lab represented at FENS!
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We are proud to share that our colleague, Dr Klaudia Lustyk, has been recognized by Jagiellonian University for significant teaching achievements in 2024/2025! 🎓 Congratulations, Klaudia! 👏 #NCURELab #TeachingExcellence #JagiellonianUniversity
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Behind the scenes of our ongoing MINIATURA project funded by the National Science Centre, Poland. We are exploring how dopamine D2 receptor signaling shapes cognitive flexibility using touchscreen-based cognitive testing in mice. 🧠🔬 #Neuroscience #D2Receptor #Research
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New review paper out! 🚀 “Restorative or disruptive? Effects of antidepressants on sleep architecture in depression” Proud to highlight the contribution of Neuropharm students Anna Szynkarek, Weronika Tyrybon & Maria Karcz. link.springer.com/article/10… #sleepresearch #depression
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We’re excited to share that nCure is a co-organizer of the 6th European Symposium on Sigma-1 Receptors! 📍 Kraków, Poland 📅 9–11 June 2026 🏛️ Jagiellonian University Looking forward to bringing together the Sigma-1 research community in Kraków! 🇵🇱
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🐰 Happy Easter from the Laboratory of Experimental Neuropharmacology Wishing you a peaceful Easter and a joyful holiday break. May spring bring fresh energy, new ideas, and inspiration in both work and everyday life ✨
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Great news! 🎉 SSG Neuropharm students, supervised in @ncure_lab (Faculty of Pharmacy JU MC), received a student research grant to study the molecular effects of MG-7 in the prefrontal cortex after a mouse model of chronic stress. Congrats to the team! 👏
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Wishing you a peaceful, joyful holiday season and well-deserved rest. Stay healthy and inspired! ✨
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Our new paper in Neurotherapeutics shows that the multimodal compound HBK-15 reverses memory deficits under NMDA receptor hypofunction via sigma-1 receptor activation. Read more: linkedin.com/posts/laborator… #neuropharmacology #sigma1receptor #HBK15 #ncurelab
#neuropharmacology #sigma1receptor #hbk15 #ncurelab | Laboratory of Experimental Neuropharmacology

#neuropharmacology #sigma1receptor #hbk15 #ncurelab | Laboratory of Experimental Neuropharmacology

✨ HBK-15 reverses memory deficits and restores hippocampal plasticity✨ Over the past few years, our team at Wydział Farmaceutyczny UJ CM has been investigating whether and how HBK-15, a multimodal...

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Every lab starts with a question. Ours at #ncurelab is how receptor signaling can lead to new therapies for mood and cognition. Follow us as we build our lab, showcase discoveries, and connect with others through shared ideas. #neuropharmacology #neuroscience
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