Nested aims to advance precision oncology medicine by finding new driver mutations hiding in plain sight to reach a broader group of patients.

Cambridge, Massachusetts
Joined March 2022
Nested Therapeutics retweeted
Watch first author Meagan B. Ryan discuss her research article, NST-628 is a novel and potent pan-RAF-MEK inhibitor, published simultaneously at #AACR24: vimeo.com/932606757/4d0bd5aa… @nestedtx
Just published with the #AACR24 New Drugs on the Horizon presentation— The pan-RAF-MEK Non-degrading #MolecularGlue NST-628 Is a Potent and Brain-penetrant Inhibitor of the RAS-MAPK Pathway with Activity Across Diverse RAS- and RAF-driven Cancers bit.ly/3Jbh9mh @nestedtx
4
1
10
7,004
Nested Therapeutics retweeted
AACR24: Having entered the clinic last night, @nestedtx's CEO discusses the preclinical profile of a brain-penetrant, pan-RAF/MEK molecular glue. #AACR24 Full video: biotechtv.com/post/nested-th…
2
2
8
3,477
Nested Therapeutics retweeted
FDA clears @nestedtx Nested Therapeutics' IND application for NST-628, a promising treatment for solid tumors. #oncology #cancerresearch #FDA #FDANews #OncWeekly buff.ly/4cCnhBI
2
1
132
Nested Therapeutics retweeted
Just published with the #AACR24 New Drugs on the Horizon presentation— The pan-RAF-MEK Non-degrading #MolecularGlue NST-628 Is a Potent and Brain-penetrant Inhibitor of the RAS-MAPK Pathway with Activity Across Diverse RAS- and RAF-driven Cancers bit.ly/3Jbh9mh @nestedtx
1
11
2
24
10,711
Nested Therapeutics retweeted
Congratulations to Klaus Hoeflich and co-authors at @nestedtx on this simultaneous #AACR24 publication in @CD_AACR!
Just published with the #AACR24 New Drugs on the Horizon presentation— The pan-RAF-MEK Non-degrading #MolecularGlue NST-628 Is a Potent and Brain-penetrant Inhibitor of the RAS-MAPK Pathway with Activity Across Diverse RAS- and RAF-driven Cancers bit.ly/3Jbh9mh @nestedtx
5
10
2,222
Nested Therapeutics retweeted
Our list of the best R&D-intensive startups spun out of universities in 2022 includes companies correcting misfolded proteins, creating second-generation GPCR agonists and mining cancer genomes for novel targets #NBTAcademicStartups go.nature.com/3RyvVZA rdcu.be/ds1XJ
1
9
34
7,785
Nested Therapeutics retweeted
Thanks @NatureBiotech for the great writeup! What an honor to be alongside stellar and dedicated founders, amazing investors and board, and the rigorous and relentless group of drug hunters that make up @nestedtx!
Next on our list of the best #NBTAcademicStartups spun out from academic institutions in 2022 are Cartography Biosciences and Nested Therapeutics, two startups taking a deep dive into cancer genomes to unearth new therapeutic targets nature.com/articles/d41587-0…
1
3
2
39
22,228