
VC | Serial Entrepreneur @ChamaeleonVC | Co-Host https://xitter.cf/t.co/VfY6eoof5z | Contact me through https://xitter.cf/t.co/K4E8Ih6iB9
San Francisco
Joined November 2008
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ngpedro retweeted
1/3🧵 19 days ago, we put @DevinAI to work on @PlayMonsterWalk
What happened:
- PRs/week: 52 → 879
- 48 automations
- A 24/7 self-improving system
We want to bring this to others.
Talofa is partnering with Cognition to create a program: Devin for Gaming, Cohort 1.
ngpedro retweeted
For AI to work with us, it needs to understand us
Today, we're introducing Persimmon, the first large-scale model designed to realistically simulate how people talk and interact
ngpedro retweeted
Good collaborators think beyond their immediate task. They consider where their actions and words lead: what they cause and who they affect. In our evals, Ampersand is a top model at collaborating with groups of people
ngpedro retweeted
No one changes the world alone
Introducing Ampersand - the first model built for us. Ampersand is a collaborator trained to help people achieve their individual and collective goals. In multi-month simulations, users collaborating with Ampersand accomplished more than with Fable and other frontier models
Available to everyone through our API
update
less than a week in, cfo.ai is growing faster than runway has ever grown in any month in our entire history
anyway
1. here's your obligatory launch video
2. you can now just sign up and try cfo.ai instantly. for free. no waitlist.
3. tag @arithecfo with your most unhinged financial modeling requests. she's back on duty and feeling spicy.
(and so is @gerithecfo but people won't stop asking him about his memecoin 🤷)
introducing
═══════════ 𝚌𝚏𝚘.𝚊𝚒 ═════════════
tl;dr
1/ runway is now cfo.ai
2/ you can hire @arithecfo and he can start TODAY
3/ you can give @arithecfo a test drive by replying to this thread with any ridiculous thing you want him to model for you, and he'll come back to you with a beautiful, detailed, fully wired financial model
... in 30 minutes or less
now, story time:
🧵 1/n
Proud to have Chamaeleon in leaving VCs in the Data-Driven VC Landscape and I am humbled to be named in the Top 100 Data Driven VC Thought Leaders.
The 2026 VC Digitization Journey
Where does your firm sit on the spectrum?
1. Old-school VC
- Manual workflows. Salesforce, email, spreadsheets, gut feel. Most of the global VC market still lives here
2. Productivity VC
- Modern off-the-shelf tools. Airtable, Slack, Notion. Real efficiency gains, no real intelligence layer
3. Workflow VC
- Lean teams. No dedicated engineers. Investors and operators leverage AI to build their own automations
4. Fullstack VC
- Dedicated engineering team. Proprietary data infrastructure and internal tech stack to gain real alpha
5. Quant VC
- Fully autonomous investing. AI works without human-in-the-loop. Purist, rare, contested
🎤 Excited to be speaking at Step SF 2026 - one of the most vibrant gatherings for startups, investors, and innovators.
Join me in San Francisco as I share insights on SaaS disruption and be a Pitch Final Judge, and connect with the brilliant minds shaping the future of tech 🚀
🎟️ Grab your ticket: buzz.stepsf.com
#StepSF #Speaker #Innovation #TechConference #Startups #SanFrancisco #Founders
Get in there!!! espn.com/f1/story/_/id/49028…
ngpedro retweeted
Quant VC investor @ngpedro at @chamaeleonvc argues that the data shows that targeting 10x returns is actually the best way to find 100x returns in venture.
"This is the last disagreement I have with Marc Andreessen that I haven’t won yet. And it’s a bit blasphemous, as it goes against the VC power law.
But we have a slightly different view, that you can normalize the curve of returns. The threshold that we classically define, as I mentioned earlier, is 10x after dilution for returns.
And this is because we did a bunch of back testing and analysis on it, and the logic that a model that is very good at detecting 10x returns is actually pretty good at finding 100xers as well.
So our models basically suggest that they’re both part of the same spectrum. They're in a continium rather than a disruption. And 100x'ers could be found by simply looking at the highest scoring potential 10x'ers."
ngpedro retweeted
Full conversation: youtube.com/watch?v=x7CECm3o…
Truly a pleasure to be on @ThePeelPod with @TurnerNovak.
An in-depth pod going truly under the hood at @chamaeleonvc, sharing our unique operating model and insights, including those coming from our own Mantis internal platform.
If you are interested in my thoughts on VC, LPs, quant and AI augmentation in Venture capital, among many other topics, this is a great listen.
New @ThePeelPod with Nuno at Chamaeleon
Chamaeleon is an early stage VC firm that borrows tools like factor analysis from public-market investors, operating more like a quant hedge fund than a traditional venture firm.
We talk through a bunch of data that cuts against the common narrative in venture, including why repeat founders aren't always the safer bet, why sub-$100m funds catch the majority of fund-returning deals, and why 10x might be a better target than 100x.
Thank you to @numeral, @FlexSuperApp, @Amplitude_HQ, and @merge_api for supporting this episode.
Timestamps:
1:00 When 1st time founders outperform serial entrepreneurs
8:05 Mantis: factor-driven quant model for VC
18:33 Why most VC’s are not data-driven
22:28 Top 1% VC fund performance
27:41 Early customer sentiment stronger success indicator than PMF or Team
34:09 Importance of co-investors on performance
39:42 Sub-$100M funds capture 70% of fund-returning deals each year
43:53 The AI neolab bubble
52:16 Marketing games that VC’s play
55:22 Most investors are not high conviction
56:43 Startups not raising for at least 3 years are 5x less likely to succeed. 10x less likely at 5 years.
1:00:19 Emerging managers have lowest LP interest in the last 15 years
1:11:19 LP capital is much less concentrated than in 2011
1:16:28 The importance of remaining relevant
1:21:01 You must lean into your unique edge as an investor
1:23:18 Pros/Cons of an alumni network venture strategy
1:28:29 Specialist funds outperform generalists (with a catch)
1:35:22 The data says go for 10x, not 100x returns
1:41:41 Should you start or join a VC firm today?
1:48:07 Nuno’s collection of 270+ phones
1:53:16 Racing cars (and winning championships)
ngpedro retweeted
Behind companies like DraftKings, Robinhood, and Gusto are the investors helping founders navigate uncertainty and scale what’s next. 🧠⚡
@ngpedro, Founding Partner at @chamaeleonvc and former McKinsey Senior Expert, is joining Step SF 2026 this August.
🎟️luma.com/StepSF26
May he Rest in Peace. Incredible driver - espn.com/racing/nascar/story…



















