The @NIH #HPC team plans, manages, & supports high-performance computing systems for the @IRPatNIH, including the @top500supercomp #Biowulf cluster

Bethesda, MD, USA
Joined February 2016
Congratulations to both of them-- #Biowulf Power PIs!
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A nice history of CIT featuring some info and a baby picture of #Biowulf
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When your pipelines generate HTML reports on #biowulf, you don't have to copy all the results back to your desktop to catch a glimpse. Use hpcdrive to locally mount your hpc storage and browse directly to it. hpc.nih.gov/docs/hpcdrive.ht… #TipTuesday
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Paul Gonzalez from our lab @genome_gov @IRPatNIH presenting his work on the evolution of non-coding elements associated with homeobox genes at #SICB2023 – an extremely computationally intensive study that wouldn't have been possible without being #PoweredByBiowulf! @NIH_HPC
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Sofia Barreira from our lab @genome_gov @IRPatNIH presenting her work on the evolutionary history of the nucleolar transcription factor at #SICB2023... sequence meets structure! #AlphaFold #ProteinFolding @NIH_HPC #PoweredByBiowulf
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Be careful about loading modules and activating conda environments in your bashrc. It's nice to have all your tools at your fingertips when you log in, but they don't always integrate well with each other. Load only what you need when you need it. #TipTuesday
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If you have a lot of short (<5min) jobs, bundle them up to get a bulk discount on your scheduling time. swarm's --bundle option will group them into bundles & run each bundled command in succession within a single subjob. See hpc.nih.gov/apps/swarm.html#… #TipTuesday #hpctips
You: I have a lot of samples to process. I’ll just run sbatch out of a for-loop, and then I— Us: No! Use a job array. Or even better, use swarm on #Biowulf. hpc.nih.gov/apps/swarm.html #TipTuesday #hpctips
Do you have short ( < 4 hr) jobs that you want to start quickly on #Biowulf? Consider submitting to the 'quick' partition to get priority scheduling. #TipTuesday
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There are now 5000 papers #PoweredByBiowulf! 🥳 We're proud to support the @IRPatNIH with this essential resource and looking forward to enabling many more papers to come. ☺️
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Your #biowulf job is coming up on its walltime limit, but it's not done yet 😬 What do you do? Use newwall to extend your walltime*! #TipTuesday *up to the partition time limit. other restrictions apply. see hpc.nih.gov/docs/userguide.h… for details
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The user dashboard is your #Biowulf control room. See and request changes to your groups and disk quotas. Monitor your jobs and resource utilization. hpc.nih.gov/dashboard #TipTuesday
Using network storage for temp files is like making a new trip to the store for each ingredient in your sandwich. Reduce traffic 🚦. Use local scratch instead. hpc.nih.gov/docs/userguide.h… #TipTuesday
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Congratulations!
Congratulations to @genome_gov’s @JulieSegre, who has been elected to @theNASciencesfor for her work in microbial genomics and human health! Her research has been crucial in tracking several skin diseases. Read more about her amazing research career: go.usa.gov/xtnsf
Thanks Andy! And mark this down as another @nih_hpc success story. All the assemblies ran there and the whole consortium relied on our Globus share, all during a pandemic. Hats off to them!
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GATK is one of the most-used apps on #Biowulf. Learn how to use GATK4 for your genomic variant analyses--and efficiently on the cluster!--in our new tutorial hpc.nih.gov/training/gatk_tu… @gatk_dev @IRPatNIH
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👇👇👇👇👇
Reminder (to self): Even (especially?) with computational experiments, always do a small, test experiment with your brand new code or pipeline before you unleash the awesome power of your cluster only to wait a week to realize all of your results are broken.
October's NIH/FDA COVID-19 Research Workshop featured work #PoweredByBiowulf irp.nih.gov/catalyst/v29i1/a…
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Our last W̵a̵l̵k̵ Zoom-in Consult went really well! Call in and join us next time on 10/14! It's not what you think; you'll still get one-on-one help ℹ️