@optimist1023

Microbiologist, Virologist

Joined February 2012
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7Media
If you have an idea that you genuinely think is good don’t let someone talk you out of it. If there is something you feel is good, something that means something to you try to do it because you can do your best work if you’re doing what you want to do.
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"It ain't about how hard you hit. It's about how hard you can get hit and keep moving forward; how much you can take and keep moving forward. That's how winning is done!"
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Everything will be ok in the end and if it is not ok it’s not the end
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We examined how T/F isolates of HIV-1 replicated in presence of APOBEC3F and APOBEC3G. We determined that APOBEC3F interacts with APOBEC3G through its N terminal domain & this results in protection of APOBEC3F from Vif mediated degradation
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We also demonstrated that subtype C is more susceptible than subtype B HIV-1 to combined APOBEC3F/APOBEC3G restriction and identified Vif variations influencing APOBEC3 degradation. Altogether we identified factors that affect susceptibility to APOBEC3F/APOBEC3G restriction
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Now online our latest #APOBEC3 publication from Chelico lab @ChelicoUSASK in @JVirology journals.asm.org/doi/10.1128… . Coauthored by @Mariayou_ and Shreoshri. Thanks funding agencies @CIHR_IRSC @_SHRF_ @USaskMed . @USaskResearch . Here is the 🧵 about it

Variability in HIV-1 transmitted/founder virus susceptibility to combined APOBEC3F and APOBEC3G...

APOBEC3 enzymes suppress HIV-1 infection by inducing cytosine deamination in proviral DNA but are hindered by HIV-1 Vif, which leads to APOBEC3 proteasomal degradation. Moving away from traditional...

journals.asm.org
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Train yourself to see the positive in every situation. #FridayVibes
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Mentors bring up your name and put you forward for opportunities even when you're not in the room. #DailyAllenInspirations
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#stayingpositive Everything serves His Plan. Even the closed doors. Trust Him. Something better is on the way for you.
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Jindagi hai, har mod par sawal poochegi jawab to dena hoga.
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Mentors are worth their weight in gold. Find mentors who believe in you and are willing to bring up your name and put you forward for opportunities - even when you’re not in the room.
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Keep your loved ones close. Tell them how much you love them everyday. Don’t be angry with them for too long. Life is unpredictable you might not get a chance to say sorry, thank you or I love you.
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Sometimes we just need
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Everything that is or was began with a dream.
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#positivethinking The good thing about hitting rock bottom, there’s only one way left to go and that’s UP
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#positivethinking The good thing about hitting rock bottom, there’s only one way left to go and that’s UP
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Delay is not denial it’s a signal that something better is on the way.
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